Muscle Structure and Function in Health and Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Biophysics".
Deadline for manuscript submissions: closed (28 February 2025) | Viewed by 3742
Special Issue Editor
Special Issue Information
Dear Colleagues,
Striated muscle contraction is achieved via cyclic interactions between myosin-containing thick filaments and actin-containing thin filaments. Muscle contraction is highly regulated in order to meet the body’s specific needs. The mechanism of muscle regulation has traditionally been regarded as calcium-dependent and based on the thin filament. It is now realized that both the thin and thick filaments play roles in activating the sarcomere. Many inherited diseases in skeletal and cardiac muscle originate from mutations in sarcomeric proteins. Developing rational therapeutic strategies will require a detailed understanding of the structural and functional regulations of muscles under physiological states in healthy individuals, as well as dysregulations under pathological conditions in diseases.
The aim of this Special Issue is to bring together original articles and reviews on the structural and functional regulation and dysregulation in normal and diseased cardiac and skeletal muscle tissues. Potential topics include, but are not limited to: (1) the roles of thin filament proteins in muscle regulation; (2) the roles of thick filament proteins in muscle regulation; (3) the roles of Z-line and M-line proteins in muscle regulation; (4) the roles of elastic proteins in muscle regulation; and (5) pharmaceutical and investigational interventions in muscle regulation.
Dr. Weikang Ma
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- muscle regulation
- structure
- contractility
- myosin
- actin
- titin
- myopathies
- cardiomyopathies
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
