Functional Genomics and Epigenomics of Stem Cells
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 3182
Special Issue Editors
Interests: cancer biology; developmental biology; transcription factors; cellular senescence; precision medicine
Special Issues, Collections and Topics in MDPI journals
Interests: cancer biology; developmental biology; transcription factors; cellular senescence; precision medicine
Interests: cancer biology; developmental biology; transcription factors; cellular senescence; precision medicine
Interests: cancer biology; developmental biology; transcription factors; cellular senescence; precision medicine
Interests: cancer and molecular biology; toxicology; cancer stem cells; anti-cancer drug designs
Special Issue Information
Dear Colleagues,
Emerging genomic and epigenomic functional landscapes of different origins of cells offer an opportunity for the enrichment of precise personalized medicine. Functional genomic, transcriptomic, epigenomic, and proteomic landscapes in single cells are tremendously advancing our understanding of the networks of genes and epigenetic patterns regulating development and diseases. Stem cells have the capacity to self-replicate as well as to differentiate into a variety of cell types that form the basis for organ development and tissue regeneration. These cells are important during the embryonic phase and throughout adulthood and are known to play an active role in cancer development, progression, and treatment resistance. Recent advances in technology have allowed the use of stem cells for disease modeling, drug screening, and personalized medicine. Isolation and propagation of human stem cells including embryonic stem cells (ESCs), fetal progenitors, and adult stem cells (ASCs), as well as generation of induced pluripotent stem cells (iPSCs), have led to key discoveries about human developmental and disease processes. Newly developed single-cell transcriptomics and epigenomics techniques allow for the study of individual stem cells in the context of their surroundings. It is critical to integrate new findings with known markers of health and disease for advancing treatment approaches. In this Special Issue on “Functional Genomics and Epigenomics of Stem Cells”, we are soliciting both original research articles and reviews that will update our readers on novel findings, current understanding as well as perspectives on the topic.
Sincerely,
Prof. Dr. Deodutta Roy
Dr. Kaumudi Bhawe
Dr. Jairo Ramos
Dr. Priti Roy
Dr. Jayanta Kumar Das
Guest Editors
Manuscript Submission Information
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Keywords
- genomics
- epigenomics
- stem cells
- cell therapy
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