Special Issue "Circular RNAs: Non-canonical Observations on Non-canonical RNAs"
Deadline for manuscript submissions: closed (30 November 2020).
Interests: alternative splicing; circular RNAs; cancer; epithelial-mesenchymal transition; plant molecular biology
The existence of circular RNA research among mainstream science can be ascribed to the contemporary synergism of big data and keen attention to detail by a number of research groups worldwide. Since the re-emergence of these alternatively spliced RNA transcripts, seminal advances have been made in understanding their biogenesis, interactome, and functions in diverse fields and myriad human diseases. However, the vast majority of research outputs focus on the ability of the highly stable circRNAs to interact with and impact signaling through microRNAs. This is a likely result of seminal papers in the field ascribing a few remarkable circRNAs as “miRNA sponges”. However, the stoichiometric ratio between the (often lowly expressed) circRNA and its (commonly more abundant) target is rarely in favor of a biologically relevant and functional consequence of these interactions.
It is time for yet another revolution in circRNA research to uncover functions beyond their documented ability to bind miRNAs.
This Special Issue aims to illuminate non-canonical functions for this non-canonical family of RNA molecules. As the first of its kind in the circRNA field, this issue will be widely read and, therefore, submissions are strongly encouraged from all areas on cell biology where circRNAs are emerging as key playmakers – prokaryotic, viral, eukaryotic, animal, and plant.
Assoc. Prof. Dr. Simon Conn
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- circular RNAs
- cell development
- alternative splicing