Epigenetic Control and Gene Regulatory Mechanisms in Development and Disease

Dear Colleagues,

Epigenetics refer to a wide range of regulatory mechanisms that control gene expression to determine cellular morphology and function. Such mechanisms include multi-step regulation at the level of gene transcription, post-transcription, protein translation, and post-translational control. The route to embryonic and postnatal development, and stem cell differentiation are complex and well-programmed processes that are tightly regulated at both genetic and epigenetic levels. Genetic mutations or epigenetic deregulation, in part influenced by environmental factors, may lead to impaired development and in many cases cause human diseases.

This Special Issue aims to provide an up to date platform for original research and review papers that cover subjects related to different forms of epigenetic mechanisms, including DNA, RNA, and histone modifications, regulatory RNA molecules, alternative splicing and related factors, three-dimensional chromatin structure, enhancer–promoter interactions, nucleosome remodeling, as well as the role of epigenetic factors (readers, writers, and erasers). Epigenetic mechanisms are important in development and disease and relevant subjects are welcome for submission, along with studies related to associated model systems.

Prof. Dr. Mojgan Rastegar
Guest Editor

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