Colorectal Cancer: Molecular Mechanisms and Treatment Progress
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 19
Special Issue Editor
Special Issue Information
Dear Colleagues,
Colorectal cancer (CRC) remains one of the most prevalent and deadly malignancies worldwide. Although advances in screening, diagnosis, and treatment have improved outcomes for some patients, the overall prognosis for advanced-stage CRC continues to be poor. A deeper understanding of the molecular mechanisms driving CRC is essential to identify novel therapeutic strategies and improve patient care.
This Special Issue aims to gather cutting-edge research focused on the molecular basis of colorectal cancer, including genetic and epigenetic alterations, tumor–stroma interactions, immune evasion, and resistance to therapy. We welcome original research articles and comprehensive reviews that explore signaling pathways, novel biomarkers for early detection or prognosis, and innovative approaches such as immunotherapy, targeted therapy, and personalized medicine.
By bringing together multidisciplinary contributions from both experimental and clinical perspectives, this Special Issue seeks to offer a comprehensive view of current advances in the field and promote further discoveries that may lead to more effective and tailored treatments for CRC patients. We warmly invite researchers to contribute their work to this collaborative effort.
Dr. Maurizio Capuozzo
Guest Editor
Manuscript Submission Information
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Keywords
- colorectal cancer (CRC)
- tumor microenvironment
- genetic and epigenetic alterations
- immune evasion
- targeted therapy and personalized medicine
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