Cell Therapies in Cancer Treatment

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 15 December 2025 | Viewed by 1329

Special Issue Editor


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Guest Editor
Chief Executive Officer, Enthera, Milano, Italy
Interests: induced pluripotent stem cells; epigenetics; hematopoiesis; neurogenesis; early and late stage clinical trials
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Special Issue Information

Dear Colleagues,

Cellular therapies are revolutionizing cancer treatment by improving the immune system's ability to fight tumors. Their manufacturing involves collecting a specific set of immune cells from the blood of patients and modifying them to generate a new, reinvigorated cell type capable of effectively attacking cancer cells when reinjected into patients.

Many types of cellular therapy for cancer are being explored, including CAR T cells, other genetically modified T cells, tumor-infiltrating lymphocytes (TIL), vaccines, NK cells, and macrophages.

We invite top scientists in the field of cell therapy in oncology to contribute to this issue.

Dr. Giovanni Amabile
Guest Editor

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Keywords

  • cellular therapies
  • cancer
  • immune

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Published Papers (1 paper)

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Review

20 pages, 353 KiB  
Review
Cell Therapy as a Way to Increase the Effectiveness of Hematopoietic Stem Cell Transplantation
by Ekaterina Pashkina, Elena Blinova, Maria Bykova, Alina Aktanova and Vera Denisova
Cells 2024, 13(24), 2056; https://doi.org/10.3390/cells13242056 - 12 Dec 2024
Viewed by 971
Abstract
Hematopoietic stem cell transplantation (HSCT) is a standard method for treating a number of pathologies, primarily blood diseases. Timely restoration of the immune system after HSCT is a critical factor associated with the development of complications such as relapses or secondary tumors and [...] Read more.
Hematopoietic stem cell transplantation (HSCT) is a standard method for treating a number of pathologies, primarily blood diseases. Timely restoration of the immune system after HSCT is a critical factor associated with the development of complications such as relapses or secondary tumors and various infections, as well as the graft-versus-host reaction in allogeneic transplantation, which ultimately affects the survival of patients. Introduction into the recipient’s body of immune system cells that are incapable of sensitization by recipient antigens during the period of immune reconstitution can increase the rate of restoration of the immune system, as well as reduce the risk of complications. This review presents the results of studies on cell therapy with various cell subpopulations of both bone marrow and mesenchymal origin during HSCT. Full article
(This article belongs to the Special Issue Cell Therapies in Cancer Treatment)
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