Ten Years of iPSCs: Current Status and Future Perspectives

Dear Colleagues,

The landmark finding in 2006, that lineage-restricted cells could be reprogrammed to a pluripotent state, has revolutionized the regenerative medicine field, opening new therapeutic prospects for several severe conditions. Induced pluripotent Stem Cells (iPS) can be obtained by using numerous reprogramming strategies that became step-by-step safer by avoiding the use of oncogenes and the integration of transgenes.

Pluripotent stem cells hold the greatest promise given their potential to differentiate into all the cell types of the human body and their potential as treatment of several genetic or degenerative diseases.

In this Special Issue, we invite your contributions, either in the form of original research articles, reviews, or shorter “Perspective” articles on all aspects related to the theme of “Transforming Induced Pluripotent Stem Cells into Novel Therapeutic Opportunities”. Articles with mechanistic and functional insights from a cell and molecular biological perspective are especially welcome.

Dr. Giovanni Amabile
Guest Editor

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