Chromatin and Transcriptome Signatures of Skeletal Muscle in Different Pathophysiological Settings
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Genetics and Genomics".
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 3854
Special Issue Editor
Interests: aging; stroke; skeletal muscle atrophy, growth, regeneration, and metabolism; genomics; proteomics; metabolomics; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Skeletal muscle, which accounts for 40% of total body weight, has diverse functions, including maintaining body posture and producing mobility and movement. Skeletal muscle is also essential for maintaining whole-body energy homeostasis in terms of glucose and fatty acid metabolism. Muscle tissue deteriorates with aging, both quantitatively and qualitatively, which increases the chances of falls as well as developing osteoporosis and metabolic diseases. Thus, maintaining muscle mass is important for a healthier life. Chromatin and transcriptome sequencing and microarrays—analytical techniques which can now be feasibly completed within a few days—have greatly advanced our understanding of the pathophysiology of many diseases. Essentially, such research has enabled important advances in clinical research and continues to guide treatment. This Special Issue covers topics related to DNA and RNA sequencing or microarray data of muscle tissue from any animal (invertebrates and vertebrates). Authors interested in contributing their research findings to this Special Issue are invited to provide a tentative title and author details to the Guest Editor, with the submission of full articles before 30 April 2021. Manuscripts will be subject to peer review according to the standard procedures of Animal journal. Upon manuscript submission, please indicate that your manuscript has prepared for the Special Issue “Chromatin and Transcriptome Signatures of Skeletal Muscle in Different Pathophysiological Settings”.
Dr. Junaith S. Mohamed
Guest Editor
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Keywords
- skeletal muscle
- RNA- and DNA-sequencing
- ChIP-sequencing
- microarray
- muscle wasting
- muscle weakness
- chromatin modifications
- transcriptomes
- microRNAs
- long noncoding RNAs
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