Integrated Approaches Between Metabolomics and Cellular Aging
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Aging".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 123
Special Issue Editors
Interests: cardiometabolic medicine; cardiovascular endocrinology and metabolism; preventive cardiology and rehabilitation; heart failure; cardiogeriatrics; clinical epidemiology
Special Issues, Collections and Topics in MDPI journals
2. School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527 Athens, Greece
3. NT-CardioMetabolics, Clinic for Metabolism and Athletic Performance, 47 Tirteou Street, 17564 Palaio Faliro, Greece
Interests: cardiometabolic medicine; cardiovascular endocrinology and metabolism; preventive cardiology and rehabilitation; heart failure; cardiogeriatrics; clinical epidemiology
Special Issue Information
Dear Colleagues,
This Special Issue will focus on the intersection of metabolomics and cellular aging, exploring how changes in metabolism influence aging at the cellular level and contribute to the development of age-related diseases. The issue aims to integrate the latest insights from metabolomic profiling with the biology of aging, highlighting how metabolic pathways, biomarkers, and cellular responses to oxidative stress, inflammation, and damage accumulation impact aging and cellular function.
Topics covered will include the following:
- Metabolomics in Cellular Aging: Investigating how metabolic changes occur with aging at the cellular level and how specific metabolites influence aging-related cellular processes such as senescence, mitochondrial dysfunction, and DNA damage.
- Biomarkers of Cellular Aging: Identifying and validating metabolites and metabolic pathways as biomarkers of cellular aging, and their potential use in assessing age-related diseases and healthspan.
- Cellular Mechanisms of Aging: Exploring how metabolism regulates key cellular processes involved in aging, including autophagy, apoptosis, and cell cycle control, and the role of metabolites in modulating these processes.
- Therapeutic Interventions Targeting Metabolic Pathways in Aging: Examining the potential of metabolic modulation, such as through dietary interventions, drugs, or nutraceuticals, to slow cellular aging and prevent age-related diseases, with an emphasis on the role of metabolomics in developing these interventions.
- Multi-Omics Approaches to Aging: Using integrative systems biology and multi-omics approaches to better understand the complex relationship between metabolism, aging, and cellular health, and identifying novel therapeutic strategies. Submissions are expected to include original research articles and review papers that advance our understanding of the role of metabolism in cellular aging.
Contributions that incorporate cutting-edge metabolomic technologies, explore novel aging biomarkers, and highlight therapeutic strategies for promoting healthy aging are especially welcome.
Dr. Maria Nikolaou
Guest Editor
Dr. Nikolaos Theodorakis
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolomics
- cellular aging
- senescence
- mitochondrial dysfunction
- DNA damage
- biomarkers
- metabolism
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
