Cellular and Molecular Mechanisms in Gastrointestinal Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 125
Special Issue Editors
Interests: WNT signaling, Colorectal Cancer, Metastasis, Drug resistance, Biomarker discovery, Cancer Stem Cells, Nanomedicine
Special Issues, Collections and Topics in MDPI journals
Interests: Anti-Cancer Drugs; Anti-Diabetic Drugs; Antimicrobial Resistance; Cardiovascular Disease; Endothelial Cell Physiology; Genomics; In Silico biology; Natural Compounds-based drug discovery; Peptide-based drug discovery; WNT signalling
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Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) diseases, including inflammatory conditions and cancers, remain among the leading causes of morbidity and mortality worldwide. Recent advances in molecular and cellular biology have unveiled a complex interplay between epithelial cells, immune components, stromal signals, and the microbiome that governs GI homeostasis and disease progression. This Special Issue of Cells aims to bring together cutting-edge research that deciphers the cellular and molecular underpinnings of GI diseases with a focus on translational relevance.
We welcome original research articles, reviews, and perspectives addressing topics such as epithelial–mesenchymal transition (EMT), stem cell dynamics, non-coding RNAs, drug resistance, metabolic reprogramming, and the tumor microenvironment. Emphasis will also be placed on studies leveraging novel models (e.g., organoids, spatial omics, in vivo imaging) and those identifying actionable biomarkers or therapeutic targets. Contributions highlighting advances in drug repositioning, nanomedicine, and cell signaling pathways (e.g., WNT, Hippo-YAP, and apoptotic cascades) are particularly encouraged.
Through this collection, we seek to foster interdisciplinary dialogue and uncover novel insights into GI pathogenesis, with the ultimate goal of accelerating therapeutic innovations and improving patient outcomes.
Dr. Shakti Ranjan Satapathy
Dr. Vikas Yadav
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gastrointestinal pathophysiology
- epithelial–mesenchymal transition (EMT)
- inflammation and immune regulation
- tumor microenvironment
- cell signaling pathways
- stem cell biology in GI tract
- molecular biomarkers
- organoids and disease modeling
- microbiome–host interactions
- drug discovery
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