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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Genomics in Brain Tumors

edited by

Marta Mellai

and

Renzo Boldorini

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1037 | Submission Open

Keywords: glioma; signaling pathways; metabolism; microbiota– gut– brain axis; biomarkers; therapeutics; immunotherapy

(This special issue belongs to the Section Cancer Pathophysiology)

Hybrid Molecular Imaging Approaches in Cancer: PET/CT, PET/MRI, and Beyond

edited by

Luca Urso

submission deadline 31 Jul 2026 | 1 articles | Viewed by 924 | Submission Open

Keywords: PET/CT; PET/MRI; hybrid molecular imaging; radiomics and artificial intelligence; conventional PET Radiotracers; emerging PET Radiotracers; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Novel Insights into Glioblastoma and Brain Metastases (2nd Edition)

edited by

Sanjay K. Srivastava

submission deadline 31 Jul 2026 | 1 articles | Viewed by 885 | Submission Open

Keywords: glioblastoma; brain metastasis; surgery; radiation; chemotherapy; blood– brain barrier; immunotherapy; novel targets; oncogenes; tumor heterogeneity; drug discovery

(This special issue belongs to the Section Cancer Metastasis)

Mechanisms of Therapy Resistance in Cancers—2nd Edition

edited by

Birandra K. Sinha

submission deadline 31 Jul 2026 | 1 articles | Viewed by 850 | Submission Open

Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance

(This special issue belongs to the Section Cancer Drug Development)

CRISPR in Cancer Biology and Therapy: 2nd Edition

edited by

Shun-Qing Liang

submission deadline 31 Jul 2026 | Viewed by 477 | Submission Open

Keywords: cancer drug resistance; CRISPR screens; CRISPR-related technology; base editing; prime editing; off-target analysis; adeno-associated virus

(This special issue belongs to the Section Methods and Technologies Development)

Oncological Healthcare: Emergency and Supportive/Palliative Approaches

edited by Ahmed Elsayem and Pavitra Parimala Krishnamani

submission deadline 31 Jul 2026 | 1 articles | Viewed by 451 | Submission Open

Keywords: supportive oncology; palliative care; symptom distress; emergency medicine; critical care; goals of care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Advances in Dermato-Oncology

edited by Carmen Cantisani

submission deadline 31 Jul 2026 | 1 articles | Viewed by 361 | Submission Open

Keywords: melanoma; line-field confocal optical coherence tomography (LC-OCT); confocal microscopy; dermoscopy; non-melanoma skin cancers; treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Melanoma: Pathology and Translational Research—2nd Edition

edited by

Alessio Giubellino

Carlos Torres-Cabala

and Jose A. Plaza

submission deadline 31 Jul 2026 | Viewed by 327 | Submission Open

Keywords: melanoma; histopathology; dermatopathology; molecular profiling; biomarkers; digital pathology; translational studies; cancer therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Decoding the Tumor Microenvironment: Immune Cell–Tumor Interplay in Breast Cancer

edited by Abirami Sivapiragasam and Roberto A. Leon Ferre

submission deadline 31 Jul 2026 | 1 articles | Viewed by 193 | Submission Open

Keywords: tumor microenvironment; breast cancer; immune cell– tumor interaction; immunotherapy; T cells; macrophages; dendritic cells; single-cell transcriptomics; spatial transcriptomics; artificial intelligence; prognostic biomarkers; predictive biomarkers; personalized therapy

(This special issue belongs to the Section Tumor Microenvironment)

Perioperative and Adjuvant Immunotherapy in Lung Cancer: New Strategies, Biomarkers, Patient Selection and Toxicity Management

edited by

Xabier Mielgo Rubio

Felipe Couñago

and Juan Carlos Trujillo-Reyes

submission deadline 31 Jul 2026 | Viewed by 173 | Submission Open

Keywords: non-small-cell lung cancer (NSCLC); immunotherapy; neoadjuvant treatment; adjuvant treatment; perioperatory treatment; chemotherapy; surgery; radiotherapy; toxicity; biomarkers

(This special issue belongs to the Section Tumor Microenvironment)

Disparities in Cancer Care: Advancing Equity Across the Cancer Continuum

edited by

Gladys Asiedu

and Ernie Kaninjing

submission deadline 31 Jul 2026 | Viewed by 172 | Submission Open

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Recent Developments on PET-CT in Multiple Myeloma

edited by Carmelo Caldarella

submission deadline 31 Jul 2026 | Viewed by 170 | Submission Open

Keywords: PET/CT; multiple myeloma; novel radiopharmaceuticals; radiomics; theranostics

(This special issue belongs to the Section Methods and Technologies Development)

Molecular Mechanisms of Resistance to Cancer Therapies

edited by

Amancio Carnero

and

Rikki A.M. Brown

submission deadline 31 Jul 2026 | Viewed by 153 | Submission Open

Keywords: therapy resistance; cancer heterogeneity; drug resistance mechanisms; targeted therapy resistance; immunotherapy resistance; tumor microenvironment; epigenetic reprogramming; biomarkers of resistance; clonal evolution

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical Trials for Hepatobiliary and Pancreatic Cancer Diagnosis and Treatment (2nd Edition)

edited by

Takuji Okusaka

submission deadline 31 Jul 2026 | Viewed by 151 | Submission Open

Keywords: biliary cancer; liver cancer; pancreatic cancer; clinical trial; diagnosis; surgery; neoadjuvant therapy; adjuvant therapy; radiotherapy; chemotherapy; targeted therapy; precision medicine; immunotherapy; biliary and duodenal stent; psycho-oncology; palliative and supportive care

(This special issue belongs to the Section Clinical Research of Cancer)

Hematopoietic Stem Cells and Cancer Immunotherapy

edited by Harinad B. Maganti

submission deadline 31 Jul 2026 | Viewed by 135 | Submission Open

Keywords: hematopoietic stem cell; transplantation; leukemia; cell biology; CAR-T cell therapies; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Surgical and Non-Surgical Convergence in Hepatocellular Carcinoma

edited by

Alessandro Vitale

submission deadline 31 Jul 2026 | Viewed by 135 | Submission Open

Keywords: hepatocellular carcinoma; conversion therapy; HCC treatment boundaries; surgical– non-surgical convergence; multidisciplinary HCC management

(This special issue belongs to the Section Cancer Therapy)

Advances in Electroporation-Based Technologies for Cancer Treatment

edited by

Bostjan Markelc

and

Gregor Sersa

submission deadline 31 Jul 2026 | Viewed by 129 | Submission Open

Keywords: electroporation; electrochemotherapy; gene electrotransfer; interleukin-12; DNA vaccination; irreversible electroporation; cancer immunotherapy; tumor ablation

(This special issue belongs to the Section Methods and Technologies Development)

The Molecular Biology of Cholangiocarcinoma

edited by

Kevin Gaston

and Padma-Sheela Jayaraman

submission deadline 31 Jul 2026 | Viewed by 119 | Submission Open

Keywords: cholangiocarcinoma; biliary tract cancer; early detection; targeted therapy; tumour microenvironment; spatial biology; genomics; transcriptomics; proteomics

(This special issue belongs to the Section Molecular Cancer Biology)

Artificial Intelligence in Radiation Therapy for Head and Neck Cancers: Prediction, Personalization, and Precision

edited by Meysam Tavakoli

submission deadline 31 Jul 2026 | Viewed by 117 | Submission Open

Keywords: head and neck cancer; radiation therapy; artificial intelligence ; machine learning ; deep learning ; toxicity prediction ; radiomics ; dosiomics ; outcome modeling ; personalized radiotherapy

(This special issue belongs to the Section Methods and Technologies Development)

Mitochondrial Metabolism and Cancer

edited by

Marcos Roberto de Oliveira

submission deadline 31 Jul 2026 | Viewed by 111 | Submission Open

Keywords: mitochondria; mitochondrial metabolism; cancer; bioenergetics; metabolomics; proteomics; mitochondrial dynamics; therapeutic targets; drug resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Microsatellite Instability in Colorectal Cancer

edited by

Joan Maurel

and Vicente Alonso-Orduña

submission deadline 31 Jul 2026 | Viewed by 105 | Submission Open

Keywords: microsatellite instability; colorectal cancer; immune checkpoint inhibitors; immune signatures

(This special issue belongs to the Section Tumor Microenvironment)

Current Applications and Cutting-Edge Innovations in Neuroendoscopy for Oncological Neurosurgery: Where Are We and Where Are We Going?

edited by Giuseppe Roberto Giammalva, Giovanni Tringali and Giuseppe Cinalli

submission deadline 31 Jul 2026 | Viewed by 103 | Submission Open

Keywords: neuroendoscopy; endoventricular surgery; skull base surgery; endoscopic assisted neurosurgery; innovations

(This special issue belongs to the Section Methods and Technologies Development)

Epigenetics: A New Approach to Cancer Therapy

edited by

Sibaji Sarkar

submission deadline 31 Jul 2026 | Viewed by 103 | Submission Open

Keywords: epigenetics; targets; cancer; tumor; signaling regulation; inhibitors; drugs

(This special issue belongs to the Section Cancer Therapy)

Pheochromocytoma and Paraganglioma: Molecular Insights and Clinical Frontiers

edited by

Ivana Jochmanová

submission deadline 31 Jul 2026 | Viewed by 98 | Submission Open

Keywords: pheochromocytoma and paraganglioma; hereditary cancer syndromes; genetic mutations; genotype– phenotype correlations; functional imaging; molecular diagnostics; biomarkers; precision oncology; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Perioperative Care and Pain Management in Cancer Patients: From Basic Science to Clinical Practice—2nd Edition

edited by

Dario Bugada

submission deadline 31 Jul 2026 | Viewed by 95 | Submission Open

Keywords: perioperative care; cancer anesthesia; analgesia; pain management

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Nanomedicine for Cancer Treatment

edited by Youssef Wahib Naguib

submission deadline 31 Jul 2026 | Viewed by 93 | Submission Open

Keywords: cancer nanomedicine; CRISPR/CAS9 nanomedicine; immune checkpoint inhibitors; cancer immunotherapy; targeted therapeutics; targeted nanoparticles; cell-penetrating peptides

(This special issue belongs to the Section Cancer Drug Development)

Multi-Omics Approaches to Tumor Antigen Discovery and Immunotherapy Target Identification

edited by

Esen Yonca Bassoy

and Parvin Zamani

submission deadline 31 Jul 2026 | Viewed by 91 | Submission Open

Keywords: tumor antigen discovery; multi-omics integration; cancer immunotherapy; spatial transcriptomics; tumor microenvironment; translational immunology

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Tumorigenesis and Tumor Microenvironment—Insights and Interventions (TTMII)

edited by

Renu Wadhwa

Sunil C. Kaul

and

Ajaikumar B. Kunnumakkara

submission deadline 31 Jul 2026 | Viewed by 89 | Submission Open

Keywords: tumorigenesis; tumor microenvironment; intervention; stress biology; aging; mortalin; CARF; ashwagandha; propolis; curcumin; natural compounds

(This special issue belongs to the Section Tumor Microenvironment)

Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) in Patients with Cancers

edited by Caterina Alati and Martina Pitea

submission deadline 31 Jul 2026 | Viewed by 79 | Submission Open

Keywords: hematopoietic stem cell; hematologic malignancies; transplantation; immunotherapy

(This special issue belongs to the Section Transplant Oncology)

Contemporary Practices in Immunotherapy-Guided Management of Lung Cancer

edited by Eleni Karapanagiotou, Nikolaos Syrigos and Umair Mahmood

submission deadline 31 Jul 2026 | Viewed by 72 | Submission Open

Keywords: lung cancer; immunotherapy; oligoprogressive disease; radiotherapy; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Multiple Myeloma and Immunology: From Pathophysiology to Therapy

edited by Marco Rossi

submission deadline 31 Jul 2026 | Viewed by 64 | Submission Open

Keywords: multiple myeloma microenvironment; immunotherapy; T cell redirecting agents; CAR-T in multiple myeloma

(This special issue belongs to the Section Tumor Microenvironment)

Digital Health and Patient-Reported Outcomes in Cancer Care

edited by Joanne Droney

submission deadline 31 Jul 2026 | Viewed by 64 | Submission Open

Keywords: patient-reported outcome measures; digital health; remote symptom monitoring; outcome-based healthcare; health-related quality of life (HRQoL); shared decision-making; real-world data collection; data standardization; health equity in digital health

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Cancer After Kidney Transplant

edited by Sławomir Lizakowski

submission deadline 31 Jul 2026 | Viewed by 53 | Submission Open

Keywords: immunosuppression; virus-associated cancer; skin cancer; graft survival; kidney transplantation; post-transplantation lymphoproliferative disorder

(This special issue belongs to the Section Transplant Oncology)

The Role of Peptidases in Cancer

edited by

Natalia A. Ignatenko

submission deadline 31 Jul 2026 | Viewed by 53 | Submission Open

Keywords: signaling proteases; proteolytic pathways; proteases and tumor microenvironment; protease diagnostic and therapeutic modalities in cancer

(This special issue belongs to the Section Molecular Cancer Biology)

Combination Therapies in Breast Cancer Chemotherapy: Chemoradiation, Targeted Agents, and Immunotherapy

edited by

Piotr J. Wysocki

submission deadline 31 Jul 2026 | Viewed by 43 | Submission Open

Keywords: breast cancer; combination therapy; endocrine therapy; chemoradiation; monoclonal antibodies; antibody– drug conjugates (ADCs); small-molecule kinase inhibitors; immunotherapy; predictive biomarkers; therapy resistance; precision oncology; translational research

(This special issue belongs to the Section Cancer Therapy)

Radiation Exposure and Cancer

edited by

Noriaki Yoshida

submission deadline 31 Jul 2026 | Viewed by 22 | Submission Open

Keywords: radiation; cancer; epidemiology; clinical research; molecular biology; exposomics

Recent Advances and Emerging Directions in Lung Cancer Radiotherapy

edited by Arturo Navarro-Martín

submission deadline 31 Jul 2026 | Viewed by 12 | Submission Open

Keywords: lung cancer; hypofractionated radiotherapy; lattice; flash therapy; protons

(This special issue belongs to the Section Cancer Therapy)

From Samples to Solutions: Transforming Cancer Research and Treatment Through Biobanks

edited by Menghong Sun

submission deadline 31 Jul 2026 | Viewed by 10 | Submission Open

Keywords: tissue specimens; morphological quality assessment; precision medicine

(This special issue belongs to the Section Cancer Informatics and Big Data)

Targeted Therapy and Emerging Biomarkers for Hepatocellular Carcinoma

edited by

Farrukh Aqil

Mingdian Tan

Liliana Chemello

and Yizhi Ge

submission deadline 31 Jul 2026 | Viewed by 10 | Submission Open

Keywords: hepatocellular carcinoma; targeted therapy; emerging biomarkers; precision oncology; immunotherapy; combination therapy; molecular pathways; drug resistance

Computational Analysis of Cancer Clonal Evolution: Signatures, Determinants and Dynamics

edited by

Qiyuan Li

submission deadline 31 Jul 2026 | Submission Open

Keywords: clonal evolution in cancers; computational analysis; genetic determinants; epigenetic reprogramming; DNA methylation signatures; mutational signatures; tumor– immune microenvironment; cancer driver genes; somatic mutations; germline variants; multi-omics integration

(This special issue belongs to the Section Cancer Informatics and Big Data)

Novel Therapies in Metastatic Castration-Resistant Prostate Cancer

edited by Kathryn E. Meier

submission deadline 1 Aug 2026 | 1 articles | Viewed by 3618 | Submission Open

Keywords: signal transduction inhibitors; targeted therapies; immunotherapy; radiopharmaceuticals; PARP inhibitors; biomarker-based approaches

(This special issue belongs to the Section Cancer Therapy)

Clinical Trials and Evolving Treatment Paradigms in Urologic Cancers

edited by

Zin War Myint

submission deadline 1 Aug 2026 | Viewed by 93 | Submission Open

Keywords: urologic cancers; clinical trials; prostate cancer; bladder cancer; kidney cancer; testicular cancer; systemic therapy; meta-analysis; biomarkers; oncology innovation

(This special issue belongs to the Section Clinical Research of Cancer)

The Clinical Trials and Management of Acute Myeloid Leukemia: 2nd Edition

edited by

Margaret T. Kasner

submission deadline 7 Aug 2026 | Viewed by 62 | Submission Open

Keywords: acute myeloid leukemia; clinical trials; translational research; targeted therapies; novel agents

(This special issue belongs to the Section Clinical Research of Cancer)

Innovations in Active Surveillance Management of Early Prostate Cancer

edited by

Vincent J. Gnanapragasam

submission deadline 8 Aug 2026 | 1 articles | Viewed by 961 | Submission Open

Keywords: prostate cancer; risk stratification; active surveillance; predictive markers; personalized management; imaging; biomarkers; clinical pathways; patient outcomes; standardizing care; attrition; cohort studies

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Targeted Therapies in Sarcomas: Overcoming Resistance and Improving Outcomes

edited by

Varun Monga

and Mohammed M. Milhem

submission deadline 8 Aug 2026 | Viewed by 75 | Submission Open

Keywords: sarcoma; targeted therapy; resistance mechanisms; combination therapy; biomarkers; precision oncology; translational research; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Clinical Surgery for Hepato-Pancreato-Biliary (HPB) Cancer

edited by

Gennaro Nappo

and

Michele Pagnanelli

submission deadline 10 Aug 2026 | 10 articles | Viewed by 15635 | Submission Open

Keywords: pancreatic malignancies; HPB malignancies; pancreatic ductal adenocarcinoma; liver cholangiocarcinoma; HPB surgery; liver resection; pancreatic resection

(This special issue belongs to the Section Cancer Therapy)

Near-Infrared Photoimmunotherapy for Cancer Treatment: 2nd Edition

edited by

Hisataka Kobayashi

submission deadline 10 Aug 2026 | Viewed by 329 | Submission Open

Keywords: NIR-PIT; phototherapy; monoclonal antibody; imaging biomarker; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Bridging Translational and Clinical Oncology in Gastrointestinal Cancers: Molecular Mechanisms to Therapeutic Advances

edited by

Stavros Papadakos

Ioannis Katsaros

and

Stamatios E. Theocharis

submission deadline 10 Aug 2026 | Viewed by 123 | Submission Open

Keywords: gastrointestinal cancers; translational oncology; molecular mechanisms; biomarkers; immunotherapy; radiomics; precision medicine; therapeutic advances

(This special issue belongs to the Section Methods and Technologies Development)

The Tumorigenesis Mechanism of Breast Cancer

edited by Swayam Prabha

submission deadline 10 Aug 2026 | Viewed by 70 | Submission Open

Keywords: breast cancer; tumor microenvironment; myeloid-derived suppressor cells; immune evasion; premetastatic niche; epithelial– mesenchymal transition; PI3K/AKT/mTOR; MAPK/ERK; Wnt/β -catenin; BRCA1/2; TP53; estrogen signaling; targeted therapy; nanomedicine; biologics; precision oncology; translational research

(This special issue belongs to the Section Molecular Cancer Biology)

Research on Clinical Treatment of Mesothelioma: 2nd Edition

edited by

Giulia M. Stella

submission deadline 10 Aug 2026 | Viewed by 61 | Submission Open

Keywords: pleural mesothelioma; targeted therapy; local treatments; radiomics; genetic traits; occupational health; asbestos exposure

(This special issue belongs to the Section Clinical Research of Cancer)

Displaying special issue 951-1000 on page 20 of 25.

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