Aptamers and Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: closed (15 September 2023) | Viewed by 36314
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cancer is one of the leading causes of morbidity and mortality in the world. Recently, it was estimated that, in 2021, 20 million people would be diagnosed for the first time with cancer and 10 million more would die of cancer. Advances in diagnostic protocols and methods, as well as new therapeutic tools, have enabled a substantial increase in disease-free time and patient survival for various types of cancer. However, the increased incidence and prevalence of many types of malignant neoplasms and the poor response to treatment in many patients make new advances necessary both for the determination of markers with prognostic and diagnostic value, as well as for the establishment of new therapeutic targets. Aptamers are small, single-stranded nucleic acids that are capable of adopting complex three-dimensional structures that allow them to interact specifically and with high affinity with their target molecule. This technology has been around for more than 30 years, but it is still largely unknown in many scientific environments. However, aptamers are emerging in recent years as potential tools in these fields in clear competition with other biomolecules (mainly antibodies and small molecules) due to their high efficacy, low toxicity, and lower production costs. In recent years, numerous articles have been published describing new aptamers against tumor markers and therapeutic targets, as well as the development of new diagnostic systems using previously described aptamers. In this Special Issue, original papers and reviews related to the use of aptamers for the diagnosis and therapy of different types of tumors are presented.
We are pleased to invite you to participate in this Special Issue of Cancers by submitting an original article or revision related to your research area and, in particular, to the use of aptamers for the diagnosis and prognosis of cancer or as potential antitumor drugs.
I look forward to receiving your contributions.
Dr. Victor M. Gonzalez
Guest Editor
Manuscript Submission Information
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Keywords
- aptamer
- cancer
- diagnostic
- therapy
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