Mitochondria Metabolism and Cancer Therapy

Dear Colleagues,

Cancer is one of the most devastating and intractable diseases. Alterations of cellular metabolism, in particular of glycolysis and mitochondrial metabolism, are recognized hallmarks of most types of cancer. Adaptation of the cellular metabolism in cancer provides the necessary energy and building blocks for macromolecules, which are essential for cell proliferation. Mitochondria also regulate redox and calcium homeostasis, participate in transcriptional regulation, and govern cell death. Therefore, therapies targeting diverse mitochondrial metabolic functions have emerged as a novel potent option to enhance the efficacy of established anti-cancer treatments such as radio- and chemotherapy as well as immunotherapy. This Special Issue of Cancers will include the latest research on mitochondrial metabolism in cancer and the cancer microenvironment with a focus on the therapeutic potential of targeting mitochondrial metabolism for cancer therapy.

This Special Issue welcomes both original papers and review articles addressing one or several of the above-mentioned issues, or of the topics mentioned in the keywords listed below.

 

Prof. Dr. Barbara Kofler
Prof. Dr. Marie Arsenian-Henriksson
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.