Advances in Skin Cancer Diagnostics and Therapy: Research and Clinical Studies (2nd Edition)

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 456

Special Issue Editor


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Guest Editor
Department of Dermatology and Allergy, University Hospital, LMU Munich, 80336 Munich, Germany
Interests: dermatology; dermatosurgery; dermato-oncology; melanoma and non-melanoma skin cancer; non-invasive diagnostics in dermatology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the second edition of the previous one, entitled “Advances in Skin Cancer Diagnostics and Therapy: Research and Clinical Studies” (https://www.mdpi.com/journal/cancers/special_issues/R64Q4G0HWR).

Skin cancer remains a significant global health concern. Not only melanoma but also less deadly non-melanoma skin cancers (NMSCs) continue to increase in incidence in the general population and pose challenges in terms of both research and clinical practice. In this Special Issue, we aim to bring together leading experts in the field of skin cancer and its diagnostic methods to share their groundbreaking findings. These articles should mainly focus on the ever more important connection of novel diagnostic tools, clinical applications, and artificial intelligence in a multidisciplinary context. Thank you for joining us on this journey where we aim to provide readers with a comprehensive overview of the latest advancements in this field.

Dr. Cristel Ruini
Guest Editor

Manuscript Submission Information

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Keywords

  • non-melanoma skin cancer
  • melanoma
  • actinic keratosis
  • field cancerisation
  • medical diagnostics
  • dermatology
  • dermoscopy
  • optical coherence tomography
  • in vivo confocal microscopy
  • ex vivo confocal microscopy
  • artificial intelligence

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Published Papers (1 paper)

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Review

11 pages, 257 KiB  
Review
Predictive Factors for Sentinel Lymph Node Positivity in Melanoma Patients—The Role of Liquid Biopsy, MicroRNA and Gene Expression Profile Panels
by Federico Venturi, Elisabetta Magnaterra, Biagio Scotti, Manuela Ferracin and Emi Dika
Cancers 2025, 17(8), 1281; https://doi.org/10.3390/cancers17081281 - 10 Apr 2025
Viewed by 317
Abstract
The identification of predictive factors for sentinel lymph node (SLN) positivity in melanoma patients is crucial for accurate staging, prognosis, and personalized therapeutic decisions. This review synthesizes recent advancements in molecular and clinicopathological predictors, with a particular focus on liquid biopsy and gene [...] Read more.
The identification of predictive factors for sentinel lymph node (SLN) positivity in melanoma patients is crucial for accurate staging, prognosis, and personalized therapeutic decisions. This review synthesizes recent advancements in molecular and clinicopathological predictors, with a particular focus on liquid biopsy and gene expression profiling (GEP) tools. Emerging evidence highlights the significant role of miRNAs in melanoma progression, metastatic potential, and lymphatic spread. Clinicopathological factors such as Breslow thickness, ulceration, and mitotic rate remain critical, while GEP provides additional precision by uncovering tumor-specific molecular pathways. By integrating these tools, clinicians can improve risk stratification, reduce unnecessary procedures, and personalize management strategies. Full article
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