Translational Studies of Obesity-Associated Hepatocellular Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Pathophysiology".
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 15674
Special Issue Editors
Interests: energy balance; obesity cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hepatocellular Carcinoma (HCC) is the most prevalent form of primary liver cancer, and is among the leading causes of cancer-related deaths around the world. With a 5 year survival rate of less than 15%, HCC is etiologically associated with viral hepatitis, alcohol excess, other hepatotoxins, and metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). While hepatitis and hepatotoxins remain significant causes of HCC, its increasing incidence in many countries is associated with expansion of the obesity pandemic. HCC has been designated an obesity-associated cancer, particularly in men. This Special Issue of Cancers will focus on translational aspects of obesity-associated HCC across the spectrum, from mechanisms and prevention to diagnosis and therapeutics. Articles are invited that study obesity-associated metabolic, immunologic, inflammatory, pathologic, microbiologic, genetic, and molecular alterations that impact obesity-associated HCC as well as their therapeutic implications.
Manuscripts will be accepted up to and including March 2021 for this Special Issue, which we plan to publish on 31 March 2021.
Prof. Dr. Nathan A. BergerDr. J. Mark Brown
Guest Editors
Manuscript Submission Information
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Keywords
- hepatocellular cancer
- non-alcoholic fatty liver disease
- non-alcoholic steato hepatitis
- obesity
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