Familial Cancer and Germline Genetics

Dear Colleague, 

Both original articles and reviews are welcome. The focus of this Special Issue is two-fold. It will cover novel family studies on diverse cancers—novelty would be demonstrated through new types of familial clustering, high risk levels and statistical power, and possibly through populations not commonly reported. The technical requirements are diagnostic accuracy and unbiased selection of patients and family members. Results on germline genetics should be linked to families with either population, experimental, or in silico evidence on pathogenicity. Alternatively, large sequencing studies on defined sporadic cancers could be acceptable, particularly if justified through unique aspects such as rare cancers, whole-genome coverage, new populations, etc. Standard panel sequencing results are of lower priority.  

The guest editors will be happy to consider inquiries about article suitability (please address them to k.hemminki@dkfz.de).

Prof. Kari Hemminki
Dr. Asta Försti
Prof. Richard Houlston
Guest Editors

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