Multidisciplinary Management of Hepatocellular Carcinoma Innovations in Diagnosis, Treatment, and Prognostication

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 1866

Special Issue Editor


E-Mail Website
Guest Editor
Internal Medicine and Gastroenterology—Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy
Interests: diet; nutrition; gut microbiota; liver disease; hepatocellular carcinoma; liver cirrhosis; nonalcoholic fatty liver disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The landscape of diagnosis and treatment for hepatocellular carcinoma has dramatically changed over the last few decades, transcending beyond the concept of univocal treatment for a specific tumor stage and advancing the hierarchy of the best therapeutic choices. Emerging evidence supports the notion that hepatologists and oncologists may focus on the role of patients’ characteristics (such as liver function) and comorbidities rather than only on tumor features. Treatment personalization is therefore pivotal and should not only take into account the single case, but should also be founded on a multidisciplinary approach that includes all the professional figures involved in HCC management, such as hepatologists, oncologists, radiologists, and surgeons.

This Special Issue aims to analyze how far the paradigm of HCC management has changed. Original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: the role of liver function in the choice of a treatment for HCC,  the role of patients’ comorbidities in the management of HCC, the role of a multidisciplinary approach in HCC management; indications and contraindications to treatments (surgery, locoregional techniques, or systemic therapies), and the role of prognostic biomarkers that may change the preferred therapeutic choice.

We look forward to receiving your contributions.

Dr. Francesca Romana Ponziani
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • MASLD
  • hepatocellular carcinoma
  • liver transplantation
  • systemic therapy
  • immune checkpoint inhibitors
  • transarterial chemoembolization
  • transarterial radioembolization
  • therapeutic hierarchy

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

22 pages, 671 KiB  
Review
Update on Resection Strategies for Hepatocellular Carcinoma: A Narrative Review
by Jun Suh Lee, Hyeong Woo Choi, Ji Su Kim, Tae Yoon Lee and Young Chul Yoon
Cancers 2024, 16(23), 4093; https://doi.org/10.3390/cancers16234093 - 6 Dec 2024
Viewed by 1438
Abstract
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, the incidence of which is rising globally. Despite recent advancements in immunotherapeutic and surgical treatment modalities, the prognosis for HCC remains poor. The surgical treatment strategy for HCC comprises a multimodal effort that [...] Read more.
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, the incidence of which is rising globally. Despite recent advancements in immunotherapeutic and surgical treatment modalities, the prognosis for HCC remains poor. The surgical treatment strategy for HCC comprises a multimodal effort that ranges from ablative therapy and surgical resection to liver transplantation. Thanks to collective efforts from the surgical society, there have been rapid advances in resection strategies, such as 3D printing for surgical planning and minimally invasive techniques to minimize surgical trauma. This review examines recent advancements in surgical techniques, patient selection criteria, and perioperative management for HCC resection. The purpose of this review was to provide clinicians and researchers with an up-to-date perspective on the evolving role of surgical resection in HCC treatment, and to identify key areas for future investigation to improve patient outcomes. Full article
Show Figures

Figure 1

Back to TopTop