Tumor Models and Drug Targeting In Vitro (Volume II)

Dear Colleagues,

This Special Issue of Cancers is the second edition of the ongoing Issue entitled “Tumor Models and Drug Targeting In Vitro”, which is available at https://www.mdpi.com/journal/cancers/special_issues/tumor_model_drug_targeting

Meaningful preclinical models are of great importance in the development of new therapeutic approaches against cancers. Far too often, promising substances fail in later clinical trials. Therefore, it is appropriate to use the advantages of advanced in vitro models to enhance the clinical success of drugs identified in basic research by better predicting their responses and effectiveness in patients.

Today, technological and scientific developments allow researchers to better understand the complex biology of cancer and the molecular relationships in tumors and during metastasis. Particularly, three-dimensional tumor and metastatic models, closely mimicking the in vivo tumor tissue, have become an indispensable platform for investigating the tumor microenvironment, mechanical properties, biochemical factors, as well as dynamic cell–cell and cell–ECM interactions. These offer unique advantages in fundamental and clinical biomedical studies as well as in drug development.

This Special Issue aims to highlight recent advances in the development and applications of in vitro tumor models as alternatives for animal testing. We welcome the submission of original research and review manuscripts.

Dr. Sascha Kopp
Dr. Marcus Krüger
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• 3D in vitro tumors
• cancer metastasis modeling
• tumor engineering
• tumor-on-a-chip
• drug targeting
• drug delivery mechanisms
• tumor microenvironment
• cellular interactions