Targeted Therapies in Pancreatic Cancer—Current Landscape and Future Directions

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 224

Special Issue Editor


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Guest Editor
Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Interests: pancreatic neoplasms

Special Issue Information

Dear Colleagues,

Pancreatic cancer remains one of the most challenging malignancies to treat, with a notoriously low survival rate and often late-stage diagnosis. Recent advancements in targeted therapies offer new hope and opportunities for improved outcomes in this aggressive cancer. By honing in on specific molecular and genetic abnormalities, targeted therapies aim to disrupt cancer progression while minimizing the impact on healthy tissues. This Special Issue, titled "Targeted Therapies in Pancreatic Cancer—Current Landscape and Future Directions", seeks to explore the latest breakthroughs and ongoing research in this dynamic field. We will focus on novel therapeutic targets, including advancements in the inhibitors of KRAS and other oncogenic pathways; the role of immunotherapy; artificial intelligence and its ability to predict sensitivity to targeted agents; and personalized medicine approaches that promise to transform the landscape of pancreatic cancer treatment. Our aim is to bring together insights from leading researchers and clinicians to propel our understanding and treatment of pancreatic cancer in this rapidly evolving landscape of targeted therapies. We invite contributions that discuss innovative therapeutic strategies, novel translational research, breaking clinical trial results, and thoughtful perspectives on the future of pancreatic cancer care.

Dr. Yongwoo Dave Seo
Guest Editor

Manuscript Submission Information

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Keywords

  • pancreatic cancer
  • precision oncology
  • targeted therapies
  • immunotherapy
  • KRAS inhibitors
  • novel clinical trial design

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Published Papers

This special issue is now open for submission.
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