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Brain Sciences
Special Issues
Audiology, Hearing Loss and the Vestibular System
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Audiology, Hearing Loss and the Vestibular System

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".

Deadline for manuscript submissions: 15 December 2026 | Viewed by 1304

Special Issue Editors

Dr. Andrea Ciorba

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Guest Editor
Clinic of Audiology & ENT, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy
Interests: audiology; hearing loss; vertigo; tinnitus; hearing aids; cochlear implants
Special Issues, Collections and Topics in MDPI journals
Dr. Stavros Hatzopoulos

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Guest Editor
Clinic of Audiology & ENT, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy
Interests: auditory electrophysiology; hearing screening; teleaudiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The aim of this Special Issue is to present the latest information related to hearing loss and vertigo, which can be considered among the most prevalent chronic disabilities worldwide. Nowadays, adequate and prompt identification and rehabilitation of hearing impairment, whenever possible, are paramount, because hearing loss can seriously interfere with psychosocial development, family dynamics, and social interactions. In addition, balance problems related to the vestibular system should be swiftly identified and rehabilitated while also considering the impact these diseases have on the quality of life of children and adults.

This Special Issue strives to consolidate knowledge and stimulate further research on these topics. Papers will include original research, insightful reviews, and clinical perspectives focusing on the aforementioned topics.

Dr. Andrea Ciorba
Dr. Stavros Hatzopoulos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • audiology
  • hearing loss
  • vertigo
  • tinnitus
  • hearing aids
  • cochlear implants

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Published Papers (1 paper)

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11 pages, 1196 KB  
Hypothesis
A Unified Theory for the Development of Tinnitus Perception and Hyperacusis Based on Associative Plasticity in the Dorsal Cochlear Nucleus
by Holger Schulze and Achim Schilling
Brain Sci. 2026, 16(4), 395; https://doi.org/10.3390/brainsci16040395 - 4 Apr 2026
Viewed by 967
Abstract
Background/Objectives: Tinnitus and hyperacusis can occur together or in isolation, with hyperacusis being associated with tinnitus much more frequently than vice versa. This striking correlation between tinnitus and hyperacusis prevalence implies that there might be a common origin, such as (hidden) hearing [...] Read more.
Background/Objectives: Tinnitus and hyperacusis can occur together or in isolation, with hyperacusis being associated with tinnitus much more frequently than vice versa. This striking correlation between tinnitus and hyperacusis prevalence implies that there might be a common origin, such as (hidden) hearing loss, and possibly interrelated neural mechanisms in the pathological development of those two conditions. Here, we propose such interrelated pathological mechanisms. Methods: This is a theoretical work based solely on considerations and published data. Results: We propose a model localized in the dorsal cochlear nucleus (DCN) of the brainstem, based on classical mechanisms of Hebbian and associative plasticity known from classical conditioning. Specifically, our model proposes that hyperacusis results from the synaptic enhancement of cochlear input to the DCN, whereas chronic tinnitus results from the synaptic enhancement of somatosensory input to the DCN. Specific conditions leading to one or the other condition are discussed. Conclusions: Our model predicts that hearing loss leads to chronic tinnitus, while noise exposure (which may also cause hearing loss) leads to hyperacusis. We would like to emphasize that our aim with the proposed model is not to provide a self-contained theoretical construct, but to stimulate thought regarding possible pathological causes of tinnitus and hyperacusis that have not yet been investigated. Individual assumptions that cannot yet be substantiated by the existing literature are intended to provide impetus for future experimental studies. Full article
(This article belongs to the Special Issue Audiology, Hearing Loss and the Vestibular System)
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