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Special Issue "Etiology, Pharmacological, and Brain Stimulation Interventions for Bipolar Disorders"
Deadline for manuscript submissions: 29 February 2020.
Interests: Mood disorders including bipolar disorders and Suicide prevention; Brain stimulation interventions; Psychopharmacology; PTSD
Editorial: Improving the lives of our patients suffering from bipolar disorder
Bipolar disorder (BD) is one of the most common brain diseases that affects multiple areas of functioning and if not properly treated can cause significant impairment of function disability, suffering, and high rates of mortality from suicide or physical illnesses associated with bipolar disorder. Although studies examining either the mechanistic undertaking or therapeutics of BD have been pursued for decades, our understanding of the etiology and mechanism for bipolar disorder is still limited.
Moreover, the pharmacological treatments that were initially studied for bipolar disorder are so limited to lithium only (that was initially and specifically studied for BD). All the other available pharmacological treatments for BD (whether for manic, mixed or depressive symptoms) were originally studied and marketed for other indications, such as schizophrenia or epilepsy and then tried in BD later. This reflects the more limited research for BD. Despite BD being a major and prevalent psychiatric disorder, there is disproportionally more limited research for BD therapeutics compared to other major psychiatric disorders such as schizophrenia or major depressive disorder.
Psychopharmacological agents, the main and most common treatment for BD, are still very limited for treating bipolar depressive symptoms, which constitute the heaviest and most prevalent symptom burden for BD. Though there are more treatment options for manic episodes, decreasing side effect burden for the available treatments continues to be an important priority. With regards to brain stimulation and apart from ECT (which has more research support), most available brain stimulation and neuromodulation interventions, whether primary electric or magnetic, are still in their infancy (except for ECT).
Thus, we dedicate this special issue as a step to further our understanding of the etiology and mechanism of BD and/or to help refine or develop better therapeutics for BD. I believe that any step in the right direction can have significant impact on improving the lives of our patients suffering from BD.
As the Guest Editor of this Special Issue: “Etiology, Pharmacological, and Brain Stimulation Interventions for Bipolar Disorders,” I welcome your contribution for this special issue in this exciting and rapidly evolving field. And I thank you in advance for your interest and contributions to furthering the science in this important field!
Prof. Nagy Youssef
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Bipolar disorders
- Brain stimulation