Advances in Immunoassay Biosensing Platform for Point-of-Care Diagnostics

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 2257

Special Issue Editors


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Guest Editor
College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA
Interests: point-of-care diagnostics; immunosensors; colorimet-ric assay; surface modification; electrochemical; lateral flow device; vertical flow device; microarray technology; biothreat agents; environmental monitoring

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Guest Editor
Department of Chemical Enzymology, Faculty of Chemistry, Moscow State University, Moscow 119991, Russia
Interests: immunosensors; fluorescence; antibody; immunoanalytical techniques for food safety and environmental control

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Guest Editor
National Reference Laboratory of Veterinary Drug Residues (HZAU) and MOA Key Laboratory for the Detection of Veterinary Drug Residues in Foods, Huazhong Agricultural University, Wuhan 430070, China
Interests: rapid detection technology; veterinary drug residues; animal derived food; food safety
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Guest Editor
Cranfield Health, Cranfield University, Cranfield MK43 0AL, UK
Interests: electrochemical biosensors; biosensors for healthcare; biosensors for environmental monitoring; DNA sensors; enzymatic sensors; affinity based biosensors; antibody based biosensors; micro-electrodes and micro-electrode arrays
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Special Issue Information

Dear Colleagues,

Immunoassays are widely applied for the detection of diseases, bacteria, viruses, drugs, allergens, toxins in food, and other biomolecules. In the last several years, the clinical demand for rapid immunodiagnostics has been demonstrated in immediate proximity to minimizing the spread of infection at an early stage. In that respect, point-of-care (POC) diagnostics have been proven to be substantial portable analytical tools, especially lateral flow, vertical flow, wearable, and optical immunoassay platforms. However, the demand for highly sensitive, and accurate point-of-care platforms in clinical and low-resource settings is ever increasing. Therefore, this Special Issue, "Advances in Immunoassay Biosensing Platform for Point-of-Care Diagnostics", focuses on the recent advances in immunoassay platforms for the detection of antigens, antibodies, proteins, small molecules, DNA, and RNA with the integration of advanced or innovative detection technologies, sample processing, and labeling molecules to apply in point-of-care diagnostics. We invite submissions of research that help to advance immunoassay biosensing platforms for point-of-care diagnostics and its application for rapid diagnosis in low-resource settings.

Dr. Jasmine Devadhasan
Prof. Dr. Sergei A. Eremin
Prof. Dr. Dapeng Peng
Prof. Dr. Séamus Higson
Guest Editors

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Keywords

  • immunosensor
  • point of need
  • microarray
  • rapid detection
  • technology integration
  • sample processing
  • assay methodology
  • biomarkers
  • immunochromatographic tests
  • instrumentation

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Published Papers (1 paper)

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Research

14 pages, 4682 KiB  
Article
Highly Sensitive Magnetic-Nanoparticle-Based Immunochromatography Assay for Rapid Detection of Amantadine in Chicken and Eggs
by Huaming Li, Yanrong Lu, Linwei Zhang, Liangni Qin, Hao Wen, Xiaohui Fan and Dapeng Peng
Biosensors 2024, 14(1), 23; https://doi.org/10.3390/bios14010023 - 30 Dec 2023
Cited by 2 | Viewed by 1750
Abstract
Amantadine (AMD) is an antiviral drug that is prohibited for use in livestock and poultry. In this study, carboxyl-modified magnetic nanoparticles (MNPs) were synthesized using the solvothermal method in one step with harmless and inexpensive regents, and they were used to label monoclonal [...] Read more.
Amantadine (AMD) is an antiviral drug that is prohibited for use in livestock and poultry. In this study, carboxyl-modified magnetic nanoparticles (MNPs) were synthesized using the solvothermal method in one step with harmless and inexpensive regents, and they were used to label monoclonal antibodies (mAbs) of AMD in microwells with electrostatic adsorption. Then, a magnetic immunochromatography assay (MICA) method was successfully established. Under optimal conditions, the MICA showed a good performance, with a linear range of 0.2~10.0 µg/L. The limit of detection (LOD) was 0.068 µg/L with the instrument, and the visual LOD (vLOD) was 0.5 µg/L. There was no cross-reaction with rimantadine and ribavirin. The vLOD in real samples was 1.0 µg/kg. The developed MICA has the advantages of convenience, speed, and sensitivity, which make it suitable for the on-site rapid detection of AMD residues in chicken tissues and eggs. Full article
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