Special Issue "Polyamines in the Central Nervous System: Neurons, Glial Cells and Diseases"

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: 30 November 2019.

Special Issue Editors

Dr. Serguei Skatchkov
E-Mail Website
Guest Editor
Universidad Central del Caribe, School of Medicine, Bayamon, PR, USA
Interests: polyamines and their accumulation in astrocytes; radial glial (Müller, Bergmann) cells; polyamine regulated channels; gap junctions and hemichannels; glia-neuron signaling; gliotransmitters; agmatine; synaptic plasticity; electrophysiology; biochemistry; polyamine function in the brain in health and polyamine-associated diseases and syndromes
Dr. Rüdiger W. Veh
E-Mail
Guest Editor
Institut für Zell- und Neurobiologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin
Interests: polyamines and their accumulation in astrocytes; radial glial (Müller, Bergmann) cells; polyamine regulated channels; gap junctions and hemichannels; glia-neuron signaling; gliotransmitters; agmatine; synaptic plasticity; electrophysiology; biochemistry; polyamine function in the brain in health and polyamine-associated diseases and syndromes

Special Issue Information

Dear Colleagues,

Polyamines contribute to the pathogenesis of Alzheimer’s, Parkinson’s, and other diseases of the central nervous system (CNS), while polyamine supplementation induces regeneration of neurons and increases longevity. In the normal adult CNS, the polyamines spermidine and spermine are accumulated preferentially in astrocytic cells, not in neurons, and are key molecules regulating many receptors and channels. Recent evidence emphasizes that the localization of polyamines; their metabolites, including agmatine; and their biosynthetic enzymes in CNS (brain and retina) vary with age and are altered in diseases. This Special Issue will highlight the uneven functional distribution of polyamines in the CNS, their effects on channels and transporters, as well as their roles in CNS disorders. We invite investigators to contribute high-quality original research and review articles focused on the roles of polyamines in health and disease, concerning the biological functions of neurons, gliotransmission, and the importance in the glial system.

Dr. Serguei Skatchkov
Dr. Rüdiger W. Veh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • astrocytes
  • polyamines
  • spermine
  • spermidine
  • agmatine
  • gliotransmitters, receptors
  • channels
  • diseases
  • syndromes

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

1. Authors: Manuela Cervelli et al.
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