Molecular Biomarkers, Immune Mechanisms, and Next-Generation Immunodiagnostics in Autoimmune Diseases
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological Factors".
Deadline for manuscript submissions: 31 May 2027 | Viewed by 38
Editor
Special Issue Information
Dear Colleagues,
Autoimmune diseases comprise a diverse group of chronic disorders characterized by complex interactions among genetic susceptibility, immune dysregulation, environmental triggers, and molecular signaling pathways, ultimately leading to the breakdown of immune tolerance and the generation of pathogenic autoantibodies. Recent advances in molecular biology, molecular biomarker discovery, multi-omics technologies, and precision medicine have substantially expanded our understanding of autoimmune disease pathogenesis while enabling earlier diagnosis, improved patient stratification, disease monitoring, and personalized therapeutic decision-making.
This Special Issue aims to highlight recent advances in molecular biomarkers, immune mechanisms, and next-generation immunodiagnostics in autoimmune diseases. We welcome original research articles and comprehensive reviews addressing molecular biomarker discovery and validation, transcriptomics, proteomics, metabolomics, epigenomics, immune profiling, and other multi-omics approaches that provide novel insights into disease mechanisms and advance precision medicine. Studies describing innovative immunodiagnostic technologies, high-throughput autoantibody profiling, multiplex immunoassays, and their translational and clinical applications are also encouraged, with immunodiagnostics presented as an integral component of biomolecular research rather than its sole focus.
The Special Issue welcomes methodological advances, translational research, and state-of-the-art reviews covering the molecular mechanisms of autoimmunity, immune regulation, biomarker discovery and validation, precision medicine, and advanced immunodiagnostic approaches across a broad spectrum of autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, autoimmune thyroid diseases, Sjögren’s syndrome, inflammatory bowel diseases, and other immune-mediated disorders. By integrating fundamental biomolecular research with translational and clinical applications, this Special Issue aims to provide a comprehensive platform for advancing the understanding, diagnosis, and management of autoimmune diseases.
Dr. Yahya F. Jamous
Guest Editor
Manuscript Submission Information
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Keywords
- autoimmune diseases
- molecular biomarkers
- immune mechanisms
- multi-omics
- next-generation immunodiagnostics
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