Biomimetic Nanotechnology for Biomedical Applications—Selected Papers from NanoBio&Med 2018

A special issue of Biomimetics (ISSN 2313-7673).

Deadline for manuscript submissions: closed (28 February 2019) | Viewed by 9127

Special Issue Editors


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Guest Editor
Institute for Bioengineering of Catalonia (IBEC), Barcelona University and Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, Madrid, Spain
Interests: surface functionalization; engineering cell–material interface; biosensors and lab-on-a-chip; microfluidics; 3D bi-oprinting and 3D cell culture; organ-on-a-chip engineering
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Phantoms Foundation, 28037 Madrid, Spain
Interests: nanotechnology; bionanofabrication; nanomaterials; nanoassemblies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Emerging nanobiotechnologies can offer solutions to the current and future challenges in medicine. By covering topics from regenerative medicine, tissue engineering, drug delivery, bionanofabrication, and molecular biorecognition, this Special Issue aims to provide an update on the trends in nanomedicine and drug delivery using biomimetic approaches, and the development of novel biologically inspired devices for the safe and effective diagnosis, prevention, and treatment of disease. 

This Special Issue is cooperating with the NanoBio&Med 2018 conference (http://www.nanobiomedconf.com/NBM18/index.php). All speakers and registered participants at this conference are invited to submit a manuscript for publication.

Prof. Josep Samitier
Dr. Antonio Correia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomimetics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioinspired nanotechnologies
  • bionanofabrication
  • bio-nano measurement and microscopy
  • nanomaterials for biological and medical applications
  • nanoassemblies
  • nanostructured surfaces
  • drug delivery
  • nanobioelectronics
  • integrated systems/nanobiosensors
  • nanotoxicology
  • graphene-based applications

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Published Papers (1 paper)

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Research

13 pages, 3525 KiB  
Article
Matrix Nanopatterning Regulates Mesenchymal Differentiation through Focal Adhesion Size and Distribution According to Cell Fate
by Ignasi Casanellas, Anna Lagunas, Yolanda Vida, Ezequiel Pérez-Inestrosa, José A. Andrades, José Becerra and Josep Samitier
Biomimetics 2019, 4(2), 43; https://doi.org/10.3390/biomimetics4020043 - 25 Jun 2019
Cited by 9 | Viewed by 7516
Abstract
Extracellular matrix remodeling plays a pivotal role during mesenchyme patterning into different lineages. Tension exerted from cell membrane receptors bound to extracellular matrix ligands is transmitted by the cytoskeleton to the cell nucleus inducing gene expression. Here, we used dendrimer-based arginine–glycine–aspartic acid (RGD) [...] Read more.
Extracellular matrix remodeling plays a pivotal role during mesenchyme patterning into different lineages. Tension exerted from cell membrane receptors bound to extracellular matrix ligands is transmitted by the cytoskeleton to the cell nucleus inducing gene expression. Here, we used dendrimer-based arginine–glycine–aspartic acid (RGD) uneven nanopatterns, which allow the control of local surface adhesiveness at the nanoscale, to unveil the adhesive requirements of mesenchymal tenogenic and osteogenic commitments. Cell response was found to depend on the tension resulting from cell–substrate interactions, which affects nuclear morphology and is regulated by focal adhesion size and distribution. Full article
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