Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Animal Models of Human Pathology: Revision, Relevance and Refinements (4th Edition)
edited by
submission deadline 15 Jul 2026 | 7 articles | Viewed by 7895 | Submission Open
Keywords: animal models; biomarkers; human disease; pathology; translation; mechanisms; nephrology; gastroenterology; urology; neuroscience; cancer; experimental design; reproducibility; refinements
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Iron in Human Diseases
edited by Margherita Correnti
submission deadline 15 Jul 2026 | 4 articles | Viewed by 7871 | Submission Open
Keywords: iron metabolism; iron dysregulation; diseases; iron deficiency; iron overload
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Exploring Human Diseases Through Genomic and Genetic Analyses
edited by Fernando Regateiro and
submission deadline 15 Jul 2026 | 4 articles | Viewed by 7685 | Submission Open
Keywords: genomic and genetic analyses; genomic medicine; personalized medicine; technologies and testing methods; complex diseases; monogenic diseases; pharmacogenomics
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Photodynamic Therapy (4th Edition)
edited by
submission deadline 15 Jul 2026 | 3 articles | Viewed by 3178 | Submission Open
Keywords: antimicrobial photodynamic treatment; chronic wounds; inflammatory dermatoses; photobiology photochemistry; photochemotherapy; photosensitizing agents; skin cancer; oral mucosa
(This special issue belongs to the Section Immunology and Immunotherapy)
Extracellular Matrix in Health and Disorders (2nd Edition)
edited by
submission deadline 15 Jul 2026 | Viewed by 411 | Submission Open
Keywords: ECM; connective tissue; healthy tissues; pathological tissues; imaging; drug targets; markers; dermis; bone; tendon
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancing Pharmacogenetics and Pharmacogenomics in Pre-Clinical Research: Unveiling New Avenues for Precision Medicine
edited by and
submission deadline 30 Jul 2026 | 1 articles | Viewed by 1775 | Submission Open
Keywords: pharmacogenetics; pharmacogenomics; precision medicine; individualized medicine
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Interaction Between Microbiota and Immunity in Health and Diseases
edited by Giuseppe Merra
submission deadline 30 Jul 2026 | Viewed by 413 | Submission Open
Keywords: microbiota; microbiome; inflammation; immunity; epithelial barrier
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Immune Checkpoint Blockade and Beyond: Next-Generation Cancer Immunotherapies
edited by Wenxuan Zhang
submission deadline 30 Jul 2026 | Viewed by 228 | Submission Open
Keywords: immune checkpoint blockade; cancer immunotherapy; tumor microenvironment; immune resistance; PD-1/PD-L1; CTLA-4; combinatorial therapy; immunometabolism; biomarkers; translational oncology
(This special issue belongs to the Section Immunology and Immunotherapy)
Ovarian Physiology and Reproduction
edited by Atefeh Najafi
submission deadline 31 Jul 2026 | 7 articles | Viewed by 30360 | Submission Open
Keywords: ovarian physiology; female fertility; folliculogenesis; oocyte; hormonal regulation; endocrine disruptors; ovarian aging; genetic modifications; environmental factors and female fertility; female reproductive health and disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Traumatic CNS Injury: From Bench to Bedside (2nd Edition)
edited by
submission deadline 31 Jul 2026 | 5 articles | Viewed by 26091 | Submission Open
Keywords: neurotrauma; traumatic brain injury; translational science; bench to bedside; neuroprotection
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Novel Biomarker and Treatments for Diabetic Neuropathy
edited by Arun V. Krishnan and Tushar Issar
submission deadline 31 Jul 2026 | 9 articles | Viewed by 23491 | Submission Open
Keywords: diabetic peripheral neuropathy; type 1 diabetes; type 2 diabetes; glucagon-like peptide-1 receptor agonists; metabolic syndrome; in vivo corneal confocal microscopy; nerve ultrasonography; obesity; exercise
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions
edited by , Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan
submission deadline 31 Jul 2026 | 12 articles | Viewed by 19596 | Submission Open
Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurodegeneration No More: Cutting-Edge Technologies and Therapies in the Evolution of Neurodegenerative Disease Management—2nd Edition submission deadline 31 Jul 2026 | 10 articles | Viewed by 19073 | Submission Open
Keywords: Alzheimer’s disease; frontotemporal lobar degeneration; Parkinson’s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive, behavioral, and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity; blood-based biomarkers; disease heterogeneity; prognosis; protein aggregation; inflammation; oxidative stress; medicinal plants; phytocompounds
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics
edited by Vetriselvan Subramaniyan
submission deadline 31 Jul 2026 | 6 articles | Viewed by 18112 | Submission Open
Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research
(This special issue belongs to the Section Gene and Cell Therapy)
Biological Therapies for Asthma: Targeting Type 1 and Type 2 Inflammation
edited by Mohammad Irshad Reza and Nilesh Sudhakar Ambhore
submission deadline 31 Jul 2026 | 2 articles | Viewed by 17847 | Submission Open
Keywords: asthma endotypes; type 1 inflammation; type 2 inflammation; biological therapies for asthma; non-type 2 asthma; cytokine pathways in asthma; precision medicine in asthma; inflammatory biomarkers in asthma; Th1/Th2 immune responses
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition
edited by , Chih-Hao Shen, and
submission deadline 31 Jul 2026 | 6 articles | Viewed by 13831 | Submission Open
Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms
(This special issue belongs to the Section Molecular and Translational Medicine)
Oxidative Stress in Health and Disease
edited by Federica Mannino
submission deadline 31 Jul 2026 | 4 articles | Viewed by 12721 | Submission Open
Keywords: oxidative stress; inflammation; human diseases; apoptosis; peroxidation; DNA damage; mitochondria
(This special issue belongs to the Section Cell Biology and Pathology)
Animal Models of Neurological Disorders: Where Are We Now? (3rd Edition)
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 12482 | Submission Open
Keywords: animal model of neurological disorders; Parkinson’s disease; Alzheimer’s disease; epilepsy; seizures; Huntington’s disease; schizophrenia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition submission deadline 31 Jul 2026 | 4 articles | Viewed by 9624 | Submission Open
Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Reproductive Medicine and Health
edited by Athanasios Zikopoulos, Sofoklis Stavros and
submission deadline 31 Jul 2026 | 2 articles | Viewed by 9218 | Submission Open
Keywords: reproductive medicine; assisted reproductive technology; fertility preservation; IVF; early pregnancy; miscarriages; proteomics; metabolomics; transcriptomics; infertility; bioethics; cryopreservation; personalized medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders
edited by Raffaella Cascella
submission deadline 31 Jul 2026 | 7 articles | Viewed by 8937 | Submission Open
Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Breast Cancer Research: Charting Future Directions submission deadline 31 Jul 2026 | 7 articles | Viewed by 8496 | Submission Open
Keywords: personalized medicine; biomarkers for early detection; immunotherapy; patient-reported outcomes
(This special issue belongs to the Section Cancer Biology and Oncology)
Diagnosis, Pathogenesis and Treatment of CNS Tumors (2nd Edition)
edited by
submission deadline 31 Jul 2026 | 5 articles | Viewed by 8401 | Submission Open
Keywords: CNS tumors; diagnosis; pathogenesis; treatment; prognosis; molecular markers
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Heart–Brain Axis
edited by Teresa Soda
submission deadline 31 Jul 2026 | 5 articles | Viewed by 7687 | Submission Open
Keywords: heart–brain axis; neurocardiology; autonomic nervous system; neuroinflammation; cardiac–cerebral syndromes; psychocardiology; calcium signaling; synaptic plasticity; ion transport; translational neuroscience
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Gastrointestinal Cancers: From Microbiota Modulation to New Therapeutic Approaches—2nd Edition
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 7253 | Submission Open
Keywords: gastrointestinal cancers; microbiota; anticancer therapy; immunotherapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research on Diabetic Retinopathy
edited by
submission deadline 31 Jul 2026 | 5 articles | Viewed by 6748 | Submission Open
Keywords: diebetic retinopathy; retinal diseases; novel treatment strategies; progression; pathogenetic mechanisms; non-proliferative diabetic retinopathy; proliferative diabetic retinopathy
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Reproductive Health and Disease
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 6688 | Submission Open
Keywords: reproductive health; artificial intelligence; fertility preservation; stem cells; gene therapy; materials; meiosis; DNA double-strand break; ovarian dysfunction; nanomedicine; pregnancy complications
(This special issue belongs to the Section Molecular and Translational Medicine)
Zebrafish Models for Development and Disease—5th Edition
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 5896 | Submission Open
Keywords: disease model; drug screening model; teratogen screening; toxicological screening; neuroscience; behavior; developmental biology
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Extracellular Vesicles in Therapeutics submission deadline 31 Jul 2026 | 1 articles | Viewed by 5805 | Submission Open
Keywords: extracellular vesicles (EVs); exosomes; regenerative medicine; immunotherapy; nanocarriers; biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Central Role of Mitochondrial Oxidative Stress in the Pathophysiology of Disorders (2nd Edition)
edited by and André Quincozes-Santos
submission deadline 31 Jul 2026 | 3 articles | Viewed by 5636 | Submission Open
Keywords: mitochondrial dysfunction; reactive oxygen species; bioenergetics; mitochondrial quality control; pathologies; protective agents
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements and Challenges in Anticancer Targeted Therapy with Small Molecules
edited by Monika Papiez
submission deadline 31 Jul 2026 | 3 articles | Viewed by 4835 | Submission Open
Keywords: small molecules; cancer; anticancer targeted therapy; cancer resistance; cancer growth blockers
(This special issue belongs to the Section Cancer Biology and Oncology)
Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments, 3rd Edition
edited by and Valentina Mercurio
submission deadline 31 Jul 2026 | 5 articles | Viewed by 4503 | Submission Open
Keywords: heart failure with reduced ejection fraction; heart failure with preserved ejection fraction; pathophysiological novelties; treatment advances; pulmonary arterial hypertension; at-home follow-up of patients with heart failure
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Molecular and Translational Medicine in Japan
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 3914 | Submission Open
Keywords: molecular and translational research; targeting inflammatory cytokines; targeted drugs; skin diseases; basic mechanisms; novel therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Biology of Cancer: From Biomarkers to Targeted Therapy
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 3814 | Submission Open
Keywords: molecular biology; carcinogenesis; cancer; biomarkers; prognostic markers; predictive markers; precision medicine; targeted therapy
(This special issue belongs to the Section Cell Biology and Pathology)
Metabolic Diseases—New Markers and Treatment Pathways
edited by Anna Różańska-Walędziak
submission deadline 31 Jul 2026 | 2 articles | Viewed by 3251 | Submission Open
Keywords: metabolic diseases; diabetes; obesity; biomarkers; anti-diabetic medications
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Platelets in Human Health and Diseases
edited by Joanna Sikora
submission deadline 31 Jul 2026 | 3 articles | Viewed by 2963 | Submission Open
Keywords: platelet; hemostasis; thrombosis; antiplatelet drugs; inflammation; cancer; cardiovascular diseases
(This special issue belongs to the Section Cell Biology and Pathology)
The Development of Cancer Immunotherapy (2nd Edition)
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 2845 | Submission Open
Keywords: cancer immunotherapy; immune checkpoint inhibitors; genetically modified T-cell therapy; hematological cancers; solid tumors
(This special issue belongs to the Section Cancer Biology and Oncology)
Atrial Fibrillation: From Pathogenesis to Treatment Strategies
edited by , Theodore G. Papaioannou and
submission deadline 31 Jul 2026 | 1 articles | Viewed by 2655 | Submission Open
Keywords: atrial fibrillation; arrhythmia; ablation; PFA; radiofrequency; cryoablation; pathophysiology; pathophysiology; molecular mechanisms
(This special issue belongs to the Section Molecular and Translational Medicine)
Inflammatory Bowel Disease: Pathomechanisms, Diagnostics, and Novel Therapeutic Strategies
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 2580 | Submission Open
Keywords: inflammatory bowel disease; Crohn’s disease; bowel inflammation; targeted therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Innovative Approaches in In Vitro Models: From Design to Application
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 2446 | Submission Open
Keywords: in vitro disease models; human cell isolation and characterization; organ-on-a-chip and microfluidic systems; 3D bioprinting and tissue engineering; translational biomedical research
(This special issue belongs to the Section Biomedical Engineering and Materials)
Molecular Research on Diabetic Retinopathy (DR)
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 2252 | Submission Open
Keywords: diabetic retinopathy; molecular mechanisms; oxidative stress; inflammation; neurovascular unit; anesthesia and perioperative stress; pain and neuroinflammation; retinal organoids; therapeutic targets
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advances in Infectious and Inflammatory Diseases
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 2225 | Submission Open
Keywords: infectious diseases; inflammatory pathology; systemic and organ-specific pathology; diagnostic and comparative pathology; histopathology and tissue-based diagnosis; molecular and immunohistochemical diagnostics; host–pathogen interactions; emerging and re-emerging pathogens; clinical–pathological correlations
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Wound Healing
edited by and
submission deadline 31 Jul 2026 | 2 articles | Viewed by 2210 | Submission Open
Keywords: wound healing; scar and keloid; diabetic ulcers; multi-omics analysis for wound healing; biomaterials for wound healing; tissue engineering for wound healing; wound infection management; clinical trials and cases of wound healing
(This special issue belongs to the Section Molecular and Translational Medicine)
Strategies for Anticancer in p53 Mutated Cancers
edited by and
submission deadline 31 Jul 2026 | 1 articles | Viewed by 2195 | Submission Open
Keywords: p53; p63; p73; tumor suppressor gene; microRNA; long non-coding RNA; protein degradation; heat shock proteins; mutation; oncology
(This special issue belongs to the Section Cancer Biology and Oncology)
Genetically Determined Cardiovascular Disease
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1926 | Submission Open
Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
New Insights into Bone and Cartilage Biology (2nd Edition)
edited by Vincent Yuan
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1910 | Submission Open
Keywords: bone remodeling; cartilage degeneration; osteoporosis osteoarthritis; mitochondrial function; protein modifications; immune signaling; therapeutic strategies
(This special issue belongs to the Section Molecular and Translational Medicine)
The Latest Advancements in Tumor Drug Delivery Systems
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1792 | Submission Open
Keywords: tumor targeting; gene delivery; biomemetic drug delivery; cancer-targeting nanorobot; specific cancer cell targeting; antitumor immunotherapy; cancer nanovaccine; tumor-suppressing nanoenzyme
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Current Trends in Regenerative Medicine submission deadline 31 Jul 2026 | Viewed by 1673 | Submission Open
Keywords: regenerative medicine; stem cells; organoids; tissue engineering; gene therapy; cell therapy; biomaterials; personalized medicine
(This special issue belongs to the Section Gene and Cell Therapy)
The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation
edited by Chao Liu
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1591 | Submission Open
Keywords: renin–angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells
(This special issue belongs to the Section Immunology and Immunotherapy)
Bioactive Lipids in Disease: Diagnosis, Prognosis, and Pathophysiology
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1429 | Submission Open
Keywords: bioactive lipids; eicosanoids; endocannabinoids; lysophospholipids; sphingolipids; oxysterols; bile acids; lipidomics; pathophysiology; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
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