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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Reviews in Adipokines

edited by

Christa Büchler

submission deadline 30 Sep 2024 | 10 articles | Viewed by 34736 | Submission Open

Keywords: brown fat; beige adipocytes; fat depots; biomarker; adipokine receptors; signaling; omental adipose tissue; obesity; cancer

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Musculoskeletal Diseases: From Molecular Basis to Therapy (Volume II)

edited by

Elisa Belluzzi

and

Assunta Pozzuoli

submission deadline 30 Sep 2024 | 17 articles | Viewed by 25641 | Submission Open

Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes

(This special issue belongs to the Section Molecular and Translational Medicine)

10th Anniversary of Biomedicines—Aging Changes in Cells, Tissues and Organs

edited by

Fernando Capela e Silva

and

Célia M. Antunes

submission deadline 30 Sep 2024 | 5 articles | Viewed by 19786 | Submission Open

Keywords: aging changes; cells; tissues; organs; tissues homeostasis; diseases; senescence

(This special issue belongs to the Section Cell Biology and Pathology)

Diabetes: Comorbidities, Therapeutics and Insights

edited by

Tomislav Bulum

submission deadline 30 Sep 2024 | 14 articles | Viewed by 17737 | Submission Open

Keywords: diabetes; complications; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; biomarkers

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development

edited by

Farhad Vahid

submission deadline 30 Sep 2024 | 11 articles | Viewed by 17023 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Immunology and Immunotherapy)

Pluripotent Stem Cell: Current Understanding and Future Directions

edited by

Aline Yen Ling Wang

submission deadline 30 Sep 2024 | 8 articles | Viewed by 14591 | Submission Open

Keywords: induced pluripotent stem cells; iPSC generation; somatic reprogramming; iPSC-derived cells; cell therapy; exosome therapy; therapeutic application; drug screening

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Biomarkers and More Efficient Therapies for Sepsis

edited by

and

submission deadline 30 Sep 2024 | 9 articles | Viewed by 14511 | Submission Open

Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Latest Research in Post-COVID (Long COVID): Pathological and Treatment Studies of Sequelae and Complications—2nd Edition

edited by

César Fernández-de-las-Peñas

submission deadline 30 Sep 2024 | 10 articles | Viewed by 13400 | Submission Open

Keywords: COVID-19; long-COVID; pain; function; fatigue; dyspnoea; vaccine

(This special issue belongs to the Section Molecular and Translational Medicine)

Brain Injury: New Insights into Mechanisms and Future Promising Treatments

edited by

Kristina Pilipović

and

Petra Dolenec

submission deadline 30 Sep 2024 | 10 articles | Viewed by 12132 | Submission Open

Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advanced Research in Endometriosis 4.0

edited by

Nikolaos Machairiotis

submission deadline 30 Sep 2024 | 7 articles | Viewed by 11707 | Submission Open

Keywords: mutations; biomarkers; diagnosis; treatment; pelvic pain; endometriosis; patient care; imaging; infertility; inhibitors; comorbidity; recurrence

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances of Receptor Tyrosine Kinases in Solid Tumors

edited by

Parham Jabbarzadeh Kaboli

submission deadline 30 Sep 2024 | 4 articles | Viewed by 10814 | Submission Open

Keywords: targeted-therapy; solid tumors; receptor tyrosine kinase; tyrosine kinase inhibitor; FDA; c-MET; VEGFR; EGFR; ALK; growth factor

(This special issue belongs to the Section Molecular and Translational Medicine)

Drug-Resistant Bacterial Infections and Alternative Therapies

edited by

Vijay Singh Gondil

submission deadline 30 Sep 2024 | 7 articles | Viewed by 10688 | Submission Open

Keywords: alternative agents; antibiotics; phages; endolysins; phytochemicals; drug discovery; nanoparticles; biofilms

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Advances in 3D Printing and Biomaterials in Tissue Engineering

edited by

Olatunji Ajiteru

submission deadline 30 Sep 2024 | 5 articles | Viewed by 10559 | Submission Open

Keywords: 3D printing; biomaterials; tissue engineering; organ-on-a-chip; scaffolding; bioinks; biofabrication; wound healing; organ mimicry

(This special issue belongs to the Section Biomedical Engineering and Materials)

Diagnosis, Pathogenesis and Treatment of TAFRO Syndrome

edited by

Yasufumi Masaki

and Sadao Aoki

submission deadline 30 Sep 2024 | 8 articles | Viewed by 10114 | Submission Open

Keywords: hyper-inflammation syndrome; thrombocytopenia; anasarca; multicentric Castleman disease; renal dysfunction; cytokine; neoplasm; infection; collagen-vascular disorder

(This special issue belongs to the Section Immunology and Immunotherapy)

Epigenetic Regulation and Its Impact for Medicine

edited by

Marie Černá

submission deadline 30 Sep 2024 | 7 articles | Viewed by 9874 | Submission Open

Keywords: gene expression; DNA methylation; histone modifications; non-coding RNAs; biomarkers

(This special issue belongs to the Section Cell Biology and Pathology)

Pathomechanisms of Disturbances Underlying Chronic Disorders—2nd Edition

edited by

Dorota Formanowicz

submission deadline 30 Sep 2024 | 7 articles | Viewed by 9873 | Submission Open

Keywords: chronic disorders; atherosclerosis; inflammation; oxidative stress; lipoproteins; endothelial dysfunction; biomarkers; pathomechanisms

(This special issue belongs to the Section Immunology and Immunotherapy)

Hepatocellular Carcinoma: From Molecular Mechanisms to Novel Therapeutic Approaches

edited by

Joon Hyuk Choi

submission deadline 30 Sep 2024 | 5 articles | Viewed by 9834 | Submission Open

Keywords: hepatocellular carcinoma; primary liver cancer; molecular biology; carcinogenesis; precancerous conditions; surgical pathology; biomarkers; diagnostic imaging; targeted therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Medicinal Chemistry in Drug Design and Discovery

edited by

Małgorzata Jarończyk

submission deadline 30 Sep 2024 | 7 articles | Viewed by 9830 | Submission Open

Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Artificial Intelligence Applications in Cancer and Other Diseases

edited by

Raji Sundararajan

submission deadline 30 Sep 2024 | 7 articles | Viewed by 9127 | Submission Open

Keywords: artificial intelligence; machine learning; neural networks; deep learning; obesity; diabetes; cancer; other diseases; pathology; drug discovery

(This special issue belongs to the Section Biomedical Engineering and Materials)

Molecular Mechanisms and Novel Therapeutic Approaches for Eye Diseases

edited by

Kofi Asiedu

submission deadline 30 Sep 2024 | 6 articles | Viewed by 8875 | Submission Open

Keywords: ocular biomarkers; anterior eye therapeutics; oxidative stress; posterior eye therapeutics; corneal immunology; ocular inflammation; ocular allergies; ocular infection; neuro-ophthalmic disease.

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Molecular Mechanisms of Head and Neck Cancers

edited by

Chih-Yen Chien

and

Pei-Jen Lou

submission deadline 30 Sep 2024 | 5 articles | Viewed by 7881 | Submission Open

Keywords: HNSCC; nasopharyngeal carcinoma; oropharyngeal cancer; oral cancer; laryngeal cancer; hypopharyngeal cancer; checkpoint inhibitor recurrent and metastatic head and neck cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular and Cellular Mechanisms of Bone and Cartilage Diseases 2.0

edited by

M. Alaa Terkawi

submission deadline 30 Sep 2024 | 3 articles | Viewed by 7817 | Submission Open

Keywords: pathophysiology of bone and cartilage; therapy; osteoarthritis; rheumatoid arthritis; osteoporosis; low back pain

(This special issue belongs to the Section Cell Biology and Pathology)

Phenotypes and Endotypes in Interstitial Lung Diseases

edited by

Francesco Amati

submission deadline 30 Sep 2024 | 5 articles | Viewed by 7663 | Submission Open

(This special issue belongs to the Section Molecular and Translational Medicine)

Past, Present and Further Looking for Therapeutic Management of Pancreatic Ductal Adenocarcinoma

edited by

Gennaro Nappo

and

Niccola Funel

submission deadline 30 Sep 2024 | 5 articles | Viewed by 7439 | Submission Open

Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; treatment pancreatic cancer; chemotherapy pancreatic cancer; radiotherapy pancreatic cancer; pancreatic cancer biology; PDAC preclinical model; biomolecular markers; theragnostic molecules; target therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

New Insights in the Pathogenesis and Treatment of Chronic Kidney Disease and Its Complications

edited by

Cristina Capusa

submission deadline 30 Sep 2024 | 1 articles | Viewed by 7172 | Submission Open

Keywords: complement-mediated glomerulopathies; cardiovascular diseases; chronic kidney disease; mechanisms of kidney fibrosis; mineral metabolism abnormalities; neurologic disorders; renal anemia; vascular calcifications; therapeutic strategies to reduce CKD progression

(This special issue belongs to the Section Molecular and Translational Medicine)

Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches 2.0

edited by

Byeong Hwa Jeon

and

Hee Kyoung Joo

submission deadline 30 Sep 2024 | 3 articles | Viewed by 6705 | Submission Open

Keywords: endothelial dysfunction; endothelial activation; reactive oxygen species and lipid peroxidation; atherosclerosis; adipose tissues and obesity; hypertension; hypercholesterolemia; vascular inflammation; tumor microenvironment; new biomarker or pathophysiology; novel therapeutic approach and pharmaceuticals

(This special issue belongs to the Section Immunology and Immunotherapy)

Neurotrauma: Mechanisms, Pathways, and Emerging Therapeutic Interventions

edited by Kevin Pierre and

Brandon Lucke-Wold

submission deadline 30 Sep 2024 | 5 articles | Viewed by 6436 | Submission Open

Keywords: neurotrauma; traumatic brain injury; spinal cord injury; inflammation; oxidative stress; excitotoxicity; diagnostic biomarkers; imaging techniques; neuroprotection; neuroregeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanotechnology to Counter the Off-Target Toxicity of Therapeutics

edited by

Prakash D. Nallathamby

submission deadline 30 Sep 2024 | 2 articles | Viewed by 6333 | Submission Open

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Recent Advances in Kidney Disease in Children

edited by

Silvio Maringhini

and Demet Alaygut

submission deadline 30 Sep 2024 | 5 articles | Viewed by 5564 | Submission Open

Keywords: kidney disease; genetics of kidney disease; prevention of kidney disease; pediatric nephrology

(This special issue belongs to the Section Molecular and Translational Medicine)

MMPs and EMMPRIN/CD147 in Physiological and Pathological Processes 2.0

edited by

Eric Huet

submission deadline 30 Sep 2024 | 3 articles | Viewed by 5555 | Submission Open

Keywords: matrix metalloproteinases; EMMPRIN; tissue remodeling; cell interactions; physiopathology

(This special issue belongs to the Section Molecular and Translational Medicine)

Alzheimer's Disease—115 Years after Its Discovery 2.0

edited by

Susana Cardoso

Cristina Carvalho

and

Sónia Catarina Correia

submission deadline 30 Sep 2024 | 3 articles | Viewed by 5190 | Submission Open

Keywords: diagnostics tools; therapeutics; Alzheimer’ s disease; AD hypotheses; AD models

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diagnosis, Pathogenesis and Treatment of CNS Tumors

edited by

Dimitrios Kanakis

submission deadline 30 Sep 2024 | 4 articles | Viewed by 4981 | Submission Open

Keywords: CNS tumors; diagnosis; pathogenesis; treatment; prognosis; molecular markers

(This special issue belongs to the Section Cell Biology and Pathology)

Pancreatic Cancer: Pathomechanism, Diagnostics and Novel Treatment Options

edited by

Konstantinos Dimas

and

Dimitrios E. Magouliotis

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4848 | Submission Open

Keywords: pancreatic cancer; chemotherapy; radiotherapy; immunotherapy; research; biomarkers; novel treatment; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Telomere Biology in Human Health, Aging and Diseases

edited by

Michael Fossel

and Kurt Whittemore

submission deadline 30 Sep 2024 | 4 articles | Viewed by 4612 | Submission Open

Keywords: telomere; telomerase; gene therapy; age-related disease; dementia; cardiovascular disease; osteoarthritis; osteoporosis; renal aging; cell aging; cell senescence; epigenetics; mitochondria; aging

(This special issue belongs to the Section Cell Biology and Pathology)

Cytokines as Biomarkers for Diagnosis and Treatment of Chronic Inflammatory Conditions: Concerns, Pitfalls, Boundaries and Future Perspectives

edited by

Ljiljana Trtica Majnarić

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4425 | Submission Open

Keywords: cytokines; chronic diseases; complex conditions; elderly patient groups; malignancies; therapy; diagnostic abilities; boundaries; perspectives

(This special issue belongs to the Section Cell Biology and Pathology)

Biology of Fibroblasts and Fibrosis

edited by

Michelle Griffin

Derrick Wan

and

Michael T. Longaker

submission deadline 30 Sep 2024 | 2 articles | Viewed by 4305 | Submission Open

Keywords: fibroblasts; fibrosis; scarring; biomarkers; cancer-associated fibroblasts; regeneration; wound healing

(This special issue belongs to the Section Cell Biology and Pathology)

Transcriptomics in Human Health and Disease

edited by

Nikolas Dovrolis

and Ioannis A. Drygiannakis

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4222 | Submission Open

Keywords: transcriptomics; RNA; messenger RNA; mRNA; non-coding RNA; gene regulation; biological pathways; precision medicine; RNA sequencing; sequencing; high-throughput sequencing

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

The Interplay between Immunity and Microbiota in Human Health and Diseases (2nd Edition)

edited by

Laura Franza

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4189 | Submission Open

Keywords: immunity; microbiota; inflammation; infection; cancer; autoimmune disorders; disease

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Mechanisms and Treatments on Musculoskeletal Disorders

edited by

Wei-Bin Hsu

and

Meng-Huang Wu

submission deadline 30 Sep 2024 | 1 articles | Viewed by 3947 | Submission Open

Keywords: osteoporosis; sarcopenia; osteoblast; osteoclast; myoblast; satellite cell

(This special issue belongs to the Section Molecular and Translational Medicine)

Animal Models of Human Pathology: Revision, Relevance and Refinements (3rd Edition)

edited by

Martina Perše

submission deadline 30 Sep 2024 | 3 articles | Viewed by 3136 | Submission Open

Keywords: animal models; biomarkers; human disease; pathology; translation; mechanisms; nephrology; gastroenterology; urology; neuroscience; cancer; experimental design; reproducibility; refinements

(This special issue belongs to the Section Molecular and Translational Medicine)

Early Diagnosis and Targeted Therapy of Pancreatic Cancer

edited by Nelson Yee

submission deadline 30 Sep 2024 | 2 articles | Viewed by 3057 | Submission Open

Keywords: targeted therapy; molecular profiling; liquid biopsy; radiation therapy; immunotherapy; machine learning; early detection; extracellular vesicles; exosomes; circulating tumor cells; circulating tumor DNA; pancreatic cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Therapeutic Antibodies against Infectious Diseases

edited by Hugues Fausther-Bovendo

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2974 | Submission Open

Keywords: therapeutic antibodies; infectious diseases; mAb gene therapy; delivery routes; affordability

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Processes Underlying Pathogenesis and Advanced Therapies for Genodermatosis

edited by

Natividad Cuadrado-Corrales

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2790 | Submission Open

Keywords: genodermatosis; rare skin disease; molecular pathology; clinical diagnostic; gene therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Emerging Trends in Gastrointestinal Tract Disease Therapies

edited by

Puo-Hsien Le

, Jenwei Chou and

Chen-Shuan Chung

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2766 | Submission Open

Keywords: gut microbiota; fecal microbiota transplantation; inflammatory bowel disease; advanced endoscopy; endoscopic bariatric therapy; endoscopic anti-reflux therapy natural orifice transluminal endoscopic surgery; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

Pharmacokinetics and Pharmacodynamics of Therapeutic Biologics

edited by

Xiaoyu Yan

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2514 | Submission Open

Keywords: pharmacokinetics; pharmacodynamics; PK/PD modeling; PBPK modeling; mAb; ADC; pharmacometrics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Insights into Osteosarcoma

edited by

Fan Shen

and

Consolato M. Sergi

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2445 | Submission Open

Keywords: osteosarcoma; molecular pathology; glucose metabolism; precancerosis; bone pathology; outcome

(This special issue belongs to the Section Cell Biology and Pathology)

New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma

edited by

Evangelos Koustas

submission deadline 30 Sep 2024 | 4 articles | Viewed by 2418 | Submission Open

Keywords: checkpoint inhibitors; combinatorial treatments; hepatocellular carcinoma (HCC); immunotherapy; liver cancer; therapy; targeted therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in the Treatment of Kidney and Upper Urinary Tract Cancers: Second Edition

edited by

Łukasz Zapała

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2337 | Submission Open

Keywords: renal cancer; urothelial cancer; immunotherapy; systemic therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Signaling Networks and Gene Expression in Immune Cells

edited by

Santarsiero Anna

Vittoria Infantino

and Paolo Convertini

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2288 | Submission Open

Keywords: cell signaling; immunometabolism; metabolic reprogramming; immunity; innate immune cells; adaptive immunity; transcriptional/post-transcriptional regulation; gene expression; inflammatory process; inflammatory diseases

(This special issue belongs to the Section Immunology and Immunotherapy)

Endometrial Cancer: From Pathobiology to Treatment

edited by

Giuseppe Gullo

Gaspare Cucinella

and Valentina Billone

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2263 | Submission Open

Keywords: endometrial cancer; fertility preservation; ovarian reserve

(This special issue belongs to the Section Cancer Biology and Oncology)

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