Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Cytogenetics in Health and Diseases
edited by
submission deadline 30 Oct 2025 | Viewed by 164 | Submission Open
Keywords: genetic mutations; high-throughput sequencing; genomics; multiomics; rare diseases
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Pathological Biomarkers in Precision Medicine
edited by , Mirela A. Dobre and Tudor Groza
submission deadline 31 Oct 2025 | 7 articles | Viewed by 23354 | Submission Open
Keywords: pathological biomarkers; precision medicine; artificial intelligence; medical imaging; omics data analysis; personalized medicine; biomarker discovery; digital pathology
(This special issue belongs to the Section Cell Biology and Pathology)
Breast Cancer: New Diagnostic and Therapeutic Approaches
edited by , and Sara Bravaccini
submission deadline 31 Oct 2025 | 8 articles | Viewed by 18772 | Submission Open
Keywords: breast cancer; breast oncology; circulating tumor cells
(This special issue belongs to the Section Cancer Biology and Oncology)
Mechanisms and Pharmacological Targets for Pain
edited by Renan F. do Espírito-Santo
submission deadline 31 Oct 2025 | 4 articles | Viewed by 15057 | Submission Open
Keywords: drug discovery; chronic pain; inflammatory pain; mechanisms of action; pain pharmacology; immunomodulation; neuropathic pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases
edited by Jixin Zhong
submission deadline 31 Oct 2025 | 12 articles | Viewed by 12658 | Submission Open
Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Fetal Medicine and Neonatology submission deadline 31 Oct 2025 | 5 articles | Viewed by 12587 | Submission Open
Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices
(This special issue belongs to the Section Molecular and Translational Medicine)
Maternal-Fetal and Neonatal Medicine submission deadline 31 Oct 2025 | 2 articles | Viewed by 11742 | Submission Open
Keywords: maternal– fetal health; neonatal health; prenatal care; prenatal diagnosis; fetal growth; diabetes mellitus; hypertension; pre-eclampsia; congenital infections; gene therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Issues in Retinal Degeneration submission deadline 31 Oct 2025 | 5 articles | Viewed by 11366 | Submission Open
Keywords: retinal degeneration; age-related macular degeneration (AMD); retinitis pigmentosa (RP); diabetic retinopathy; gene therapy; stem cell therapy; retinal implants; pharmacological treatments; diagnostic methods; molecular mechanisms; predictive biomarkers; imaging technologies; signaling pathways; oxidative stress; neuroprotection
(This special issue belongs to the Section Cell Biology and Pathology)
Feature Reviews in Gastrointestinal Diseases
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 11263 | Submission Open
Keywords: precision medicine; artificial intelligence; eosinophilic gastrointestinal diseases; inflammatory bowel disease; irritable bowel syndrome; gastroesophageal reflux disease; gastrointestinal cancers; drug-resistant infections
(This special issue belongs to the Section Molecular and Translational Medicine)
Head and Neck Tumors, 4th Edition submission deadline 31 Oct 2025 | 6 articles | Viewed by 10009 | Submission Open
Keywords: head and neck tumors; predictive markers; liquid biopsy; therapy; precision medicine; biomaterials
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Mechanisms of Steroid Hormone Action—2nd Edition
edited by
submission deadline 31 Oct 2025 | 4 articles | Viewed by 9974 | Submission Open
Keywords: oestrogen; androgens; thyroid; adrenal gland; menopause; cancer
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Research in Hypertrophic Cardiomyopathy
edited by Said Alsidawi, and
submission deadline 31 Oct 2025 | 6 articles | Viewed by 9561 | Submission Open
Keywords: hypertrophic cardiomyopathy; myosin inhibitors; genetic therapy; risk stratification
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Research in Obesity, 2nd Edition
edited by Zaida Abad-Jiménez and
submission deadline 31 Oct 2025 | 3 articles | Viewed by 8997 | Submission Open
Keywords: obesity; genetics; molecular pathways; adipose tissue; metabolism; leukocytes; prevention; new targets for treatment; translational studies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Cell Signaling and Molecular Regulation in Neurodegenerative Disease
edited by Shao-Ming Wang
submission deadline 31 Oct 2025 | 2 articles | Viewed by 8838 | Submission Open
Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pathogenesis and Novel Therapeutics in Musculoskeletal Conditions, 3rd Edition submission deadline 31 Oct 2025 | 4 articles | Viewed by 8286 | Submission Open
Keywords: neck pain; low back pain; myofascial pain syndromes; chronic pain; musculoskeletal disorders; disability; pain treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo
edited by
submission deadline 31 Oct 2025 | 7 articles | Viewed by 8233 | Submission Open
Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Genetic Research on Neuropsychiatric Disorders and Complex Human Diseases
edited by Wen Zhang
submission deadline 31 Oct 2025 | 7 articles | Viewed by 8133 | Submission Open
Keywords: neuropsychiatric disorders; complex human diseases; genetic research; omics data analysis; high-throughput sequencing; machine learning; disease mechanism
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Tumor Immunology submission deadline 31 Oct 2025 | 2 articles | Viewed by 7147 | Submission Open
Keywords: tumor immunity; immunotherapy; engineered immune cells; antibodies; immunomodulators; cytokines; survival; immune-checkpoint inhibitors; tumor immune microenvironment
(This special issue belongs to the Section Immunology and Immunotherapy)
Innovative Approaches to Molecular Pathogenesis and Therapy of Lymphoid Malignancies submission deadline 31 Oct 2025 | 6 articles | Viewed by 6896 | Submission Open
Keywords: lymphoma; leukemia; myeloma; lymphoproliferative disorders; B-cell neoplasms; T-cell neoplasms; pathogenesis; molecular targets; novel therapies; translational research; tumor microenvironment
(This special issue belongs to the Section Cell Biology and Pathology)
Advanced Research in Atrial Fibrillation
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 6893 | Submission Open
Keywords: atrial fibrillation; arrhythmia; electrophysiology; cardiovascular; mechanism; laboratory; experimental
(This special issue belongs to the Section Molecular and Translational Medicine)
Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders—2nd Edition submission deadline 31 Oct 2025 | 1 articles | Viewed by 6698 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; cognitive dysfunction; multiple sclerosis; stroke; migraine; chronic pain; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; brain injuries; comorbidity; brain plasticity; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Progress in Neonatal Pulmonary Biology
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 6640 | Submission Open
Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Novel Drug Discovery, Synthesis, and Evaluation
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 5718 | Submission Open
Keywords: drug synthesis; novel therapies; disease targets; medicinal chemistry; computational methods; screening techniques; pharmaceutical development; target identification
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Epigenetic Regulation and Its Impact for Medicine (2nd Edition)
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 5639 | Submission Open
Keywords: gene expression; DNA methylation; histone modifications; non-coding RNAs; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition submission deadline 31 Oct 2025 | 5 articles | Viewed by 5417 | Submission Open
Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Liver Oncology: Molecular Mechanisms and Therapeutic Innovations
edited by , Rui Miguel Martins and
submission deadline 31 Oct 2025 | 3 articles | Viewed by 5115 | Submission Open
Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; liver metastases; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Pathogenesis and Therapeutics of Gastrointestinal Diseases
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 4842 | Submission Open
Keywords: gastrointestinal diseases; IBD; IBS; GERD; functional dyspepsia; gut microbiome
(This special issue belongs to the Section Molecular and Translational Medicine)
Gynecological Diseases in Cellular and Molecular Perspectives submission deadline 31 Oct 2025 | 3 articles | Viewed by 4718 | Submission Open
Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions
(This special issue belongs to the Section Molecular and Translational Medicine)
Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition submission deadline 31 Oct 2025 | 4 articles | Viewed by 4610 | Submission Open
Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation
(This special issue belongs to the Section Molecular and Translational Medicine)
Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 4567 | Submission Open
Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels
(This special issue belongs to the Section Biomedical Engineering and Materials)
Pathogenesis, Diagnosis, and Treatment of Respiratory Diseases
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 4475 | Submission Open
Keywords: COPD; asthma; interstitial lung disease; lung cancer; pneumonia; tuberculosis; respiratory failure; ARDS; COVID-19; obstructive sleep apnea
(This special issue belongs to the Section Cell Biology and Pathology)
Latest Advancements in Radiotherapy
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3595 | Submission Open
Keywords: radiobiology; dosimetry; nanoparticles; FLASH; radiation
(This special issue belongs to the Section Molecular and Translational Medicine)
Sphingolipid Metabolism and Signaling in Health and Diseases: 2nd Edition submission deadline 31 Oct 2025 | 2 articles | Viewed by 3377 | Submission Open
Keywords: sphingolipids; glycosphingolipids; gangliosides; sphingosine-1-phosphate; cell homeostasis; neurodegeneration; neurodevelopment; inflammation; diabetes; cystic fibrosis; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches (4th Edition)
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3074 | Submission Open
Keywords: oxidative stress; inflammation; molecular mechanisms; pharmacotherapy; longevity; aging
(This special issue belongs to the Section Immunology and Immunotherapy)
MicroRNA and Its Role in Human Health, 2nd Edition
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3014 | Submission Open
Keywords: microRNA; disease models; disease associations; molecular mechanism; molecular diagnosis; molecular therapy
(This special issue belongs to the Section Cell Biology and Pathology)
Innovative Approaches in In Vitro Skin Models: From Design to Application
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2903 | Submission Open
Keywords: in vitro skin models; tissue engineering; dermatological research; 3D skin bioprinting; skin disease modeling
(This special issue belongs to the Section Biomedical Engineering and Materials)
Recent Developments in Mycobacterial Research submission deadline 31 Oct 2025 | 2 articles | Viewed by 2706 | Submission Open
Keywords: Mycobacterium tuberculosis; mycobacterial; host immune responses
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Prostate Cancer Targeted Therapy: Highlighting Advances in Precision Medicine and Rational Combination Approaches
edited by Alan P. Lombard
submission deadline 31 Oct 2025 | 2 articles | Viewed by 2691 | Submission Open
Keywords: prostate cancer; precision medicine; targeted therapeutics; rational drug combinations; clinical biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition) submission deadline 31 Oct 2025 | 3 articles | Viewed by 2528 | Submission Open
Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Protein Misfolding and Functional Impairment in Neurodegenerative Diseases submission deadline 31 Oct 2025 | 1 articles | Viewed by 2250 | Submission Open
Keywords: protein misfolding; chaperones; energy landscape; neurodegenerative diseases; amyloidogenesis; intrinsically disordered proteins; structure prediction algorithms; bioinformatics; molecular dynamic simulations
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Hepatocellular Carcinoma Pathogenesis and Therapy
edited by Junyan Tao
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1944 | Submission Open
Keywords: HCC (hepatocellular carcinoma); early diagnosis; molecular pathology characteristics; molecular target therapy; combination therapy; immune checkpoint inhibitors; precision medicine; HCC heterogeneity; drug resistance; HCC risk factors
(This special issue belongs to the Section Cancer Biology and Oncology)
Emerging Therapeutic Strategies for Epilepsy: Bridging Research and Clinical Practice
edited by Tanveer Singh
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1917 | Submission Open
Keywords: epilepsy; status epilepticus; MRI; EEG; inhibitory neurotransmission; immunohistochemistry; gene regulation; neurodegeneration; precision medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases: 2nd Edition
edited by Aifang Cheng, Beika Zhu and Fulin Ma
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1899 | Submission Open
Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Role of Endothelial Cells in Cardiovascular Disease—2nd Edition submission deadline 31 Oct 2025 | 1 articles | Viewed by 1887 | Submission Open
Keywords: endothelial cells; endothelial dysfunction; cardiovascular disease; endothelial progenitor cells; atherosclerosis; thrombosis; vessel inflammation; regenerative medicine
(This special issue belongs to the Section Cell Biology and Pathology)
Unraveling New Horizon in Vascular Diseases: From Pathophysiology to Novel Therapeutic
edited by Miguel A. Ortega and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1886 | Submission Open
Keywords: vascular diseases; artery; venous disease; venous hypertension; heart; lymph; diabetes; surgery; immune system; translational medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Secondary Immunodeficiency in Oncohematological Diseases submission deadline 31 Oct 2025 | 1 articles | Viewed by 1843 | Submission Open
Keywords: secondary immunodeficiencies and opportunistic infections; secondary immunodeficiencies and B-lymphocytes; secondary immunodeficiencies and hematological diseases; secondary immunodeficiencies and cancers; secondary immunodeficiencies and novel cancer treatments; secondary immunodeficiencies and oxidative stress
(This special issue belongs to the Section Immunology and Immunotherapy)
Biological Role of Oxidative Stress in Inflammatory Processes submission deadline 31 Oct 2025 | 1 articles | Viewed by 1790 | Submission Open
Keywords: oxidative stress; redox balance; antioxidants; NRF2; microbiota; bilirubin; Tlr4; inflammation
(This special issue belongs to the Section Cell Biology and Pathology)
Sex Hormones and Cardiovascular Diseases: From Pathophysiology to Novel Therapeutic Approaches submission deadline 31 Oct 2025 | 1 articles | Viewed by 1753 | Submission Open
Keywords: endogenous sex hormones; aging; sexual dimorphism; hormone replacement therapy; CVDs; hypertension; myocardial infarction; atherosclerosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Anticancer Inhibitors and Targeted Therapy submission deadline 31 Oct 2025 | 2 articles | Viewed by 1739 | Submission Open
Keywords: histone deacetylases (HDACs); YAP signaling; targeted therapy; oncogenic signaling; biomarker discovery; small-molecule inhibitors; cancer drug resistance; epigenetic therapy
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Age-Related Diseases: Molecular Mechanisms, Treatments, and Clinical Implications submission deadline 31 Oct 2025 | 1 articles | Viewed by 1602 | Submission Open
Keywords: aging; age-related diseases; cellular senescence; mitochondrial dysfunction; inflammation and oxidative stress; biomarkers; precision medicine; pharmacological interventions; healthy aging; translational geriatric research
(This special issue belongs to the Section Molecular and Translational Medicine)
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