The Molecular Mechanisms Underlying the Activation and Regulation of Signaling Pathways in Cancer

Dear Colleagues,

Cancer is a complex and multifaceted disease, with signaling pathways playing a crucial role in its development and progression. In this Special Issue, we aim to explore the intricate molecular mechanisms that underlie the activation and regulation of signaling pathways in cancer.

We invite leading researchers, experts, and scholars in the field to contribute their valuable insights and research findings to this Special Issue. By bringing together a collection of high-quality contributions, this special Issue aims to advance our understanding of the molecular mechanisms underlying signaling pathway dysregulation in cancer and provide insights into potential therapeutic interventions. We welcome original research articles, reviews, and perspectives that delve into the molecular basis of signaling pathways in cancer, including, but not limited to, the following topics:

• Key signaling pathways implicated in cancer development and progression;
• Crosstalk and interactions between different signaling pathways in cancer cells;
• Post-translational modifications and their impact on signaling pathway activation in cancer;
• Molecular regulators and modulators of signaling pathway activity in cancer;
• Novel therapeutic targets and strategies based on signaling pathway dysregulation in cancer.

Dr. Emanuele Giurisato
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• activation
• regulation
• signaling pathways
• cancer
• post-translational modifications
• molecular regulators
• therapeutic targets
• signaling pathway dysregulation