Special Issue "Circadian Disruption and Metabolic Disorders"
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: 16 August 2020.
Interests: signal transduction; gene expression; circadian clock; obesity; metabolic syndrome
Combined human and genetic studies have shown that disturbed sleep and circadian rhythms are associated with metabolic disease. The cellular circadian clock is unique in generating daily rhythms of sleep, feeding, and metabolism in synchrony with the environmental light cycle, thereby playing a critical role in human health.
The misalignment between central and peripheral clock systems, which is a result of mistimed feeding caused by high-fat diet, shiftwork, jet-lag, and sleep curtailment, contributes to the pathobiology linking circadian and sleep disorders with metabolic disease. In light of these observations, the circadian clock is likely to have important implications for the development of specific preventive, diagnostic, prognostic, and powerful therapeutic strategies toward a number of pathologies. Indeed, while still in its infancy, emerging evidence indicates that targeting circadian biology through the appropriate timing of light exposure, food intake, exercise, and sleep can lead to improved metabolic fitness and positively impact health. The increased discovery and use of circadian biomarkers and their accuracy in measuring internal circadian body time will undoubtedly lead to novel and personalized treatments for healthcare according to the individual’s circadian clock in the future.
This Special Issue invites original research articles and reviews that cover all aspects of the field, with the aim to improve our understanding of how disruption of the clocks promotes metabolic disorders. We are particularly interested in fundamental investigations using experimental animal models as well as translational studies. Moreover, this Special Issue welcomes the submission of manuscripts focusing on circadian biomarkers of interest for the diagnosis, the prediction of the severity, but also on the therapy and benefits from timed interventions for metabolic disorders.
Dr. Eléonore Maury
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- circadian clock
- clock genes
- rhythmic transcriptomic, proteomics and metabolomics, epigenetics
- circadian disruption, circadian misalignment
- metabolism, metabolic disease
- chrononutrition, time-restricted eating, chronopharmacology, chronomedicine