Molecular Targets and Targeting in Biomedical Sciences

Dear Colleagues,

The personalized medicine endorsed by the remarkable breakthrough of genomic and proteomic technologies during the last decades will hopefully enable the fashioning of preventive, diagnostic, prognostic, and curative medicine, according to the individual’s genetic and molecular profile. Such tremendous progress in biomedical concepts will have an overwhelming impact on patient healthcare, both by preventing or limiting the medication side effects and reducing the healthcare costs as a result of an improved disease outcome.

The biomarkers represent key players in personalized medicine, and they are defined by the FDA-NIH Biomarker Working Group as a measurable molecular signature of normal or pathogenic processes, or as a therapeutic outcome of medical intervention. Among them, molecular biomarkers serve as targets for the development of molecularly targeted imaging probes and therapeutics through a wide range of library-based display technologies. But what are the real progresses, challenges, and perspectives of all of these modern tools of molecular biology for biomedical research in general and for patient care in particular?

This Special Issue welcomes the submission of original research and review manuscripts focusing on biomarkers of interest for the diagnosis, therapy, and theranostics of a wide range of pathologies, but also on the specific technologies employed in their identification and targeting, helping us to achieve a realistic overview of this exciting and interdisciplinary field of biomedical research.

Prof. Dr. Carmen Burtea
Prof. Dr. Sven Saussez
Prof. Dr. Marc Port
Guest Editors

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