ATP-dependent Chromatin Remodeler
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: closed (31 May 2020) | Viewed by 30357
Special Issue Editor
Special Issue Information
Dear Colleagues,
One of the major types of epigenetic factors is the large family of ATP-dependent chromatin remodeling complexes that reorganize chromatin by moving nucleosomes on DNA, disassembling and reassembling nucleosomes, or dynamically exchanging into chromatin different histone variants such as histone H2A.Z. Recent advances in high resolution cryo-electron microscopy have provided critical insights into the mechanisms of chromatin remodeling that also complement biochemical approaches used for this purpose. Advances in genomics/next generation DNA sequencing and molecular genetics has revealed that these chromatin remodelers are important in development and differentiation and when mutated can become the molecular basis for several diseases including cancer. In this issue, we will examine the convergence of these two distinct areas and how they inform us as to the importance and roles of these factors for regulating the epigenome and its impact on human diseases.
Prof. Blaine Bartholomew
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- chromatin
- nuclear organization and architecture
- chromatin dynamics
- nucleosome
- histone variants
- genomics
- epigenomics
- chromatin remodeling
- transcription regulation
- genomic integrity and maintenance