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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Drug Design and Delivery for Neuropsychological Disorders: Integrating Bioinformatics and Nanotechnology

edited by

Tahmineh Mokhtari

submission deadline 31 Jan 2026 | Viewed by 71 | Submission Open

Keywords: neuropsychological disorders; drug design; drug delivery; bioinformatics; nanotechnology; computational drug design; targeted therapies; neuropharmacology; nanomedicine; bioengineering

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advances in Spinal Biomechanics: Integrating In Vivo, In Vitro, and Computational Approaches in the Era of Evolving Spine Technologies

edited by

Byung Ho Lee

submission deadline 31 Jan 2026 | Viewed by 71 | Submission Open

Keywords: spinal biomechanics; computational modelling; spinal disorders; implants; finite element modeling

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Imaging Techniques for Neuroscience

edited by Dhairya A. Lakhani

submission deadline 31 Jan 2026 | Viewed by 70 | Submission Open

Keywords: machine learning; functional MRI (fMRI); resting-state fMRI; ultra-high-field MRI; connectomics; MR spectroscopy; molecular imaging; MR perfusion; high-grade glioma; ischemic stroke; vessel wall imaging; neurodegenerative disease; PET/MR

(This special issue belongs to the Section Biosignal Processing)

Advancing Care in Neuroimmunology: The Role of Digital Tools in Multiple Sclerosis and Related Disorders

edited by

Tjalf Ziemssen

submission deadline 31 Jan 2026 | Viewed by 69 | Submission Open

Keywords: multiple sclerosis (MS); neuromyelitis optica spectrum disorders (NMOSD); autoimmune encephalitides; neuroimmunological diseases; mobile health (mHealth) applications; wearable sensors; telemedicine; artificial intelligence (AI)-based diagnostic support; digital biomarkers

(This special issue belongs to the Section Biosignal Processing)

Integrative Approaches: The Intersection of Brain–Computer Interfaces and Retinal Health

edited by Mouayad Masalkhi

submission deadline 31 Jan 2026 | Viewed by 68 | Submission Open

Keywords: brain– computer interfaces; retinal disorders; ophthalmology; visual prosthetics; assistive technologies; neurotechnology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Cardiothoracic Assist Devices

edited by Suvitesh Luthra and

Enrique Berjano

submission deadline 31 Jan 2026 | Viewed by 67 | Submission Open

Keywords: mechanical circulatory support; VAD; OCS; LBE and EVLP; total artificial heart; heart failure; maglev and axial flow pumps; minimally invasive; wireless power; biocompatibility; AI in cardiac devices

(This special issue belongs to the Section Regenerative Engineering)

Biomechanical Assessment in Rehabilitation and Performance

edited by

Eleftherios Paraskevopoulos

and

Dimitris G. Mandalidis

submission deadline 31 Jan 2026 | Viewed by 65 | Submission Open

Keywords: motion capture analysis; postural control assessment; gait analysis; wearable sensor technologies; muscle activation studies; joint kinematics; sports injuries; sports therapy

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Motor Control Techniques: Integrating Motor Neuroscience and Applied Mathematics

edited by

Osmar Pinto Neto

submission deadline 31 Jan 2026 | Viewed by 55 | Submission Open

Keywords: motor control; computational neuroscience; neural oscillations; electromyography (EMG); neuromodulation (tDCS; TMS); Bayesian models; motor learning and adaptation; biomechanics; rehabilitation engineering; Parkinson's disease

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomedical Materials Expansion in Tissue Regeneration: Material and Tissue Evaluation

edited by

Osamu Yamamoto

and Takahiro Kawai

submission deadline 31 Jan 2026 | Viewed by 39 | Submission Open

Keywords: polymers; metals; gels; collagen; in vivo/in vitro evaluation; cells; animal model; clinical trial; biological tissue regeneration

(This special issue belongs to the Section Regenerative Engineering)

Emerging Applications and Insights for Life and Biomaterial Sciences Through Correlated Volume and Electron Microscopy Advances

edited by

Eduardo Rosa-Molinar

and Mark Sanders

submission deadline 10 Feb 2026 | Viewed by 105 | Submission Open

Keywords: resin electron microscopy; volume electron microscopy; correlated electron microscopy; in situ electron microscopy; analytical electron microscopy; correlated cryo-electron tomography

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Platforms for Drug Delivery

edited by Anam Ahsan

submission deadline 20 Feb 2026 | Viewed by 570 | Submission Open

Keywords: biomaterials; drug delivery; nanotechnology; nanobiotechnology; bioengineering platforms; targeted drug delivery; chemotherapy; bioconjugation; disease management; therapeutic agents

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Wearable Devices for Neurotechnology

edited by Basilio Vescio and

Fabiano Bini

submission deadline 25 Feb 2026 | Viewed by 113 | Submission Open

Keywords: wearable devices; neurotechnology; brain– computer interfaces; EEG; wearable gait analysis

(This special issue belongs to the Section Biosignal Processing)

Musculoskeletal Function in Health and Disease

edited by Adrian Paul Harrison and Else Marie Bartels

submission deadline 28 Feb 2026 | 4 articles | Viewed by 10188 | Submission Open

Keywords: musculoskeletal disorders; muscle injury; pre-habilitation and rehabilitation; healthcare; wearable technology; quality of life; sport science; sport medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advancements in Wound Healing and Repair

edited by

Wing Sum Siu

submission deadline 28 Feb 2026 | 4 articles | Viewed by 9311 | Submission Open

Keywords: wound healing; wound repair; bioactive dressings; stem cell therapy; tissue engineering; chronic wounds; biomaterials; imaging technologies; nanoparticles; antibacterial properties; biopolymers; wound dressing; cell and molecular biology

(This special issue belongs to the Section Regenerative Engineering)

Intelligent Wearable and Implantable Devices for Biomedical Applications

edited by Milad Zamani and

Dante Mantini

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7587 | Submission Open

Keywords: bio-inspired and neuromorphic computation; spiking neural networks; biosensor devices and interface circuits; bioelectronics; biosensors; biotelemetry

(This special issue belongs to the Section Biosignal Processing)

Application of Artificial Intelligence in Complex Diseases

edited by Yan Zhu

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7467 | Submission Open

Keywords: artificial intelligence; machine learning; complex diseases; healthcare; diagnostics; predictive modeling; medical imaging; ethics in AI

(This special issue belongs to the Section Biosignal Processing)

Deciphering Medicine: The Role of Explainable Artificial Intelligence in Healthcare Innovations, 2nd Edition

edited by

Mohamed Shehata

and

Mostafa Elhosseini

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6865 | Submission Open

Keywords: deciphering medicine; explainable AI; machine learning; deep learning; medical diagnostics and treatment

(This special issue belongs to the Section Biosignal Processing)

New Sights of EEG and Brain Diseases: Updates and Directions

edited by

Carlos Trenado

and Christian Penaloza

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6345 | Submission Open

Keywords: EEG; brain diseases; neuropsychiatric conditions; prosthetics

(This special issue belongs to the Section Biosignal Processing)

Cutting-Edge Applications of Machine and Deep Learning in Biomedical Signal and Image Processing

edited by

Pedro Miguel Rodrigues

, Bruno Bispo and Joaquim Celestino

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5854 | Submission Open

Keywords: biosignal analysis; medical image analysis; machine learning; deep learning; wearable bio-technology

(This special issue belongs to the Section Biosignal Processing)

Advances and Innovations in Wound Repair and Regeneration

edited by

Shiva Akbarzadeh

and

Azam Ali

submission deadline 28 Feb 2026 | 4 articles | Viewed by 5406 | Submission Open

Keywords: engineered skin graft; three-dimensional skin printing; skin grafting in animal models; dermal substitutes

(This special issue belongs to the Section Regenerative Engineering)

Artificial Intelligence-Based Medical Imaging Processing

edited by Xin Meng and Yuxiang Zhou

submission deadline 28 Feb 2026 | 5 articles | Viewed by 5042 | Submission Open

Keywords: artificial intelligence; medical imaging; disease detection and prediction; quantitative analysis; clinical integration; bias resilience; model transparency; precision medicine

(This special issue belongs to the Section Biosignal Processing)

Physical Therapy and Rehabilitation

edited by

Seong-Gil Kim

and Jin-Seop Kim

submission deadline 28 Feb 2026 | 5 articles | Viewed by 4803 | Submission Open

Keywords: physical therapy; rehabilitation; exercise prescription; manual therapy; telerehabilitation; telehealth; virtual reality; wearable devices; musculoskeletal rehabilitation; neurological rehabilitation; post-operative recovery; chronic pain management; injury prevention; multidisciplinary rehabilitation; patient-centered care; personalized rehabilitation; functional recovery; mobility improvement; pain alleviation; mental health in rehabilitation; long-term wellness

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Mathematical Models for Medical Diagnosis and Testing

edited by

Peiyuan Zhou

and

Andrew K. C. Wong

submission deadline 28 Feb 2026 | 6 articles | Viewed by 4711 | Submission Open

Keywords: mathematical modeling; machine learning; artificial intelligence; pattern discovery; medical diagnosis; clinical data analysis; predictive analytics; explainable AI; statistical modeling; anomaly detection; rare disease detection; knowledge discovery; health informatics

(This special issue belongs to the Section Biosignal Processing)

Recent Progress in Craniofacial Regeneration

edited by

Chengfei Zhang

and

Zhaoming Wu

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4418 | Submission Open

Keywords: craniofacial regeneration; regenerative medicine; tissue engineering; craniofacial stem cells; organoid; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Modern Medical Imaging in Disease Diagnosis Applications

edited by Carlo Cosimo Quattrocchi and

Marco Parillo

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3995 | Submission Open

Keywords: radiology; diagnostic imaging; contrast media; computed tomography; magnetic resonance imaging; ultrasound; artificial intelligence in medical imaging; radiomics

(This special issue belongs to the Section Biosignal Processing)

Biomechanics and Mechanobiology in Cell and Tissue Engineering

edited by

Aaron Baker

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3445 | Submission Open

Keywords: biomechanics; mechanobiology; tissue engineering; cell engineering; vascular; cardiovascular; neuroengineering; stem cells; cancer; osteoarthritis; bone

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Microalgal Systems for a Greener Future

edited by

Ana Filipa Cruz Esteves

and

Alok Kumar Patel

submission deadline 28 Feb 2026 | 4 articles | Viewed by 3281 | Submission Open

Keywords: artificial intelligence; machine learning; bioprocessing; circular bioeconomy; production value addition; biomass valorization; microalgal cultivation systems; sustainable bioprocessing

(This special issue belongs to the Section Biochemical Engineering)

Biomaterials and Technology for Oral and Dental Health

edited by

Gherlone Felice Enrico

and

Giulia Teté

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3069 | Submission Open

Keywords: biomaterials; odontoiatria; oral and dental health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Insights in Tissue Engineering: Novel Developments, Current Challenges, and Future Perspectives

edited by

Philippe Abdel-Sayed

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3048 | Submission Open

Keywords: bioprinting; organ-on-chip; stem cells; vascularization; regeneration; tissue engineering; scaffold; biomaterials; organoids; ATMP

(This special issue belongs to the Section Regenerative Engineering)

Deep Learning in Medical Applications: Challenges and Opportunities

edited by Richard Bayford,

Sikandar Ali

and

Ali Hussain

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2593 | Submission Open

Keywords: deep learning; medical imaging; healthcare; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Recent Progress in Stem Cells and Stem Cell-Derived Biotherapeutics for Regenerative Medicine Applications

edited by

Johnson Rajasingh

and Arghya Paul

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2331 | Submission Open

Keywords: stem cells; extracellular vesicles; exosomes; regenerative medicine; induced pluripotent stem cells; disease model; mesenchymal stem cells

(This special issue belongs to the Section Regenerative Engineering)

New Trends in Biomechanical Modeling in Musculoskeletal Disorders and Diseases

edited by

Philippe Gorce

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1695 | Submission Open

Keywords: musculoskeletal disorders; musculoskeletal diseases; injury biomechanics; muscle biomechanics dynamic and kinematic modeling; gait and posture; muscle electromyography; motion analysis; postural control and balance; occupational health; occupational ergonomics; sport medicine; sport performance; quality of life

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Machine Learning and Artificial Intelligence in Pediatric Healthcare

edited by

Hammad Ashraf Ganatra

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1330 | Submission Open

Keywords: artificial intelligence; machine learning; pediatrics; natural language processing; diagnostics

(This special issue belongs to the Section Biosignal Processing)

IoT Technology in Bioengineering Applications: Second Edition

edited by Mihaela Hnatiuc and Larbi Boubchir

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1238 | Submission Open

Keywords: robotic device; signal processing; image processing; communication protocol; embedded system; smart sensors; cloud/FOG; predictive methods; monitoring; process optimization; diagnosis; implant; tele surgery; teleconsultation; telemonitoring

(This special issue belongs to the Section Biosignal Processing)

Transcranial Direct Current Stimulation: Bridging Bioengineering and Neuroscience for Brain Health

edited by

Josué Fernández-Carnero

and

Víctor Navarro López

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1082 | Submission Open

Keywords: transcranial direct current stimulation (tDCS); neuroplasticity; neuromodulation

(This special issue belongs to the Section Biosignal Processing)

The Next Generation of Tissue Engineering

edited by Tetsuya Imamura

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1031 | Submission Open

Keywords: tissue engineering; mesenchymal stem cells; engineered cell sheets; biofabricated cell structures

(This special issue belongs to the Section Regenerative Engineering)

Diagnostic Tools and Therapeutic Strategies for Hip Diseases

edited by Antonio Capone and

Giuseppe Marongiu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 989 | Submission Open

Keywords: hip disease; coxarthrosis; arthritis; joint inflammatory disease; total hip arthroplasty; hip revision surgery; 3D printing; 3D modeling; advanced diagnostic imaging; tribology; finite element analysis

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Robotic-Assisted Rehabilitation

edited by

Hongwu Wang

submission deadline 28 Feb 2026 | 1 articles | Viewed by 876 | Submission Open

Keywords: robotics-assisted rehabilitation; neurological rehabilitation robotics; wearable robotics; exoskeletons and assistive robotics; adaptive control in robotics; human– robot interaction; AI and machine learning in rehabilitation; translational studies in rehabilitation robotics; ethical considerations in rehabilitation robotics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Cognitive Decline and Its Transversality: Potential Mechanisms and Modulators of Disease

edited by

Cinzia Coppola

and

Elisabetta Signoriello

submission deadline 28 Feb 2026 | Viewed by 347 | Submission Open

Keywords: cognitive decline; Alzheimer’ s disease; fronto-temporal lobar degeneration; Lewy body disease; multiple sclerosis; protein misfolding; amyloid; tauopathy; neuroinflammation; microglia; astroglia; synaptopathy; CSF biomarkers; plasmatic biomarkers; micro-RNA or miRNA; long noncoding RNA or lncRNA; heart– brain axis; gut– brain axis; cerebrovascular disease; hippocampal atrophy; structural and functional neuroimaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Sights of Image Processing and Digital Models in Biomedicine

edited by Seyed Jalalddelin Mousavirad and

Diego Oliva

submission deadline 28 Feb 2026 | Viewed by 325 | Submission Open

Keywords: image processing and computer vision; deep learning; artificial intelligence; biomedicine

(This special issue belongs to the Section Biosignal Processing)

Neuromorphic Computing in Bioengineering Applications

edited by William C. Tang and Nathan Leroux

submission deadline 28 Feb 2026 | Viewed by 303 | Submission Open

Keywords: neuromorphic computing; bioengineering; hardware design and architectures; algorithms and models; AI; machine learning; neuromorphic sensors; neuromorphic interfaces; energy-efficient systems; neural network models; computational neuroscience

(This special issue belongs to the Section Biosignal Processing)

Advanced Restorative Dental Materials and Implant Technologies

edited by

Elena-Raluca Baciu

Alice Mirela Murariu

and

Gabriela Luminița Gelețu

submission deadline 28 Feb 2026 | Viewed by 281 | Submission Open

Keywords: biomaterials; restorative dentistry; dental implants; patient specific implants; nanotechnology; guided tissue regeneration; digital dentistry; minimally invasive techniques; 3D printing

(This special issue belongs to the Section Regenerative Engineering)

Advancements in Human–Machine Interaction and Robotics: From Biomechanics to Cognitive Neuroscience

edited by Jiejunyi Liang

submission deadline 28 Feb 2026 | Viewed by 279 | Submission Open

Keywords: human-machine interaction; robotics; biomechanics; cognitive neuroscience; anthropomorphic robotic systems

Advancing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Through Computer-Aided Drug Design

edited by

Chin-Hung Lai

and

Suraj Narayan Mali

submission deadline 28 Feb 2026 | Viewed by 265 | Submission Open

Keywords: molecular docking; molecular dynamics; QSAR; AI; NSAIDs

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

New Sight of Deep Learning in Bioengineering: Updates and Future Directions (2nd Edition)

edited by

Tao Zhang

submission deadline 28 Feb 2026 | Viewed by 251 | Submission Open

Keywords: deep learning; biomedicine; robotics and biomechanics; biomedical imaging; biosignal processing

(This special issue belongs to the Section Biosignal Processing)

Advancements and Innovations in Photoacoustic Imaging: Pioneering Techniques and Clinical Applications in Biomedical Research

edited by

Praveen Kumar Panangattukara Prabhakaran

Taeho Kim

and

Dong-Kwon Lim

submission deadline 28 Feb 2026 | Viewed by 239 | Submission Open

Keywords: tomography; deep tissue imaging; photoacoustic imaging; contrast agents; probes; nanoparticles; clinical applications; multimode imaging

(This special issue belongs to the Section Biosignal Processing)

Bioengineered Contact Lenses: Therapeutics, Biosensing, and Smart Interfaces

edited by

Ahmed Abass

submission deadline 28 Feb 2026 | Viewed by 226 | Submission Open

Keywords: contact lenses; vision correction; refractive error; smart contact lenses; drug delivery; biosensors; ocular physiology; corneal biomechanics; tear film; biocompatibility; biomedical engineering; responsive materials; wireless systems; myopia management and control; presbyopia; lens design; ocular surface; clinical applications; advanced manufacturing; digital health; mobile health apps

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Wearable Technologies and Health Informatics: Advancements in Bioengineering

edited by

Iqram Hussain

and

Jahowa Islam

submission deadline 28 Feb 2026 | Viewed by 170 | Submission Open

Keywords: wearable sensors; health monitoring; large language model; electronic health record; flexible sensors; sensors; artificial intelligence; smart healthcare; data privacy; machine learning; sensor applications; energy efficiency; health diagnostics; wearable signal processing (EEG; ECG; EMG; PPG; and IMU); internet of things (IoT); activity recognition; biomedical techniques; sleep medicine; smart grid; data science; smart surveillance

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Approaches in Lung Injury and Repair

edited by