Recent Prospects on Functional Biomaterials

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 4810

Special Issue Editors


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Guest Editor
Faculty of Materials Science and Engineering, Technical University "Gheorghe Asachi" of Iasi, Iasi, Romania
Interests: sustainability; sustainable development; energy; efficiency; environmental impact; sustainable engineering and design; green buildings; energy efficiency; building performance; building materials; building acoustics; life cycle assessment; embodied energy
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Guest Editor
Departamentul de Tehnologii şi Echipamente pentru Procesarea Materialelor, Universitatea Tehnica Gh. Asachi din IasI, Iasi, Romania
Interests: biomaterials; testing and material expertise; medical devices; surface engineering; tissue–implant interaction
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The global need for the use and obtainment of more efficient and safer biomaterials is growing considerably, being in close correlation with the annual growth of the world population, the growing number of elderly people and the functional demands raised by the younger population.

Currently, the performances of biomaterials are obtained by newly developed biomaterials, or conventionally can be improved by modifying the surface characteristics from a morphological/topographical point of view and/or by functional coatings. This major need to modify the surface of implants derives from the desire to improve the osseointegration capacity of biomaterials in order to reduce bacterial adhesion and inflammatory response.

The aim of this Special Issue entitled “Recent Prospects on Functional Biomaterials” is to make relevant work known to our colleagues in the biomaterials field. All recent articles on new functional biomaterials for medical applications and research progress on metallic biomaterials is welcome to be published and shared, including but not limited to natural and synthetic polymers and bio-inert and bioactive ceramics

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Synthesis, characterization, and applications of new biomaterials, tissue engineering etc.;
  • Mechanical coating/alloying/treatment of metallic and non-metallic materials;
  • Implantable systems: design and reactions.

Dr. Mădălina Simona Bălțatu
Prof. Dr. Petricǎ Vizureanu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • new biomaterials
  • biocompatibility
  • controlled reactions
  • implants

Published Papers (3 papers)

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Research

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19 pages, 11365 KiB  
Article
Study on Surface Roughness, Morphology, and Wettability of Laser-Modified Powder Metallurgy-Processed Ti-Graphite Composite Intended for Dental Application
by Peter Šugár, Richard Antala, Jana Šugárová, Jaroslav Kováčik and Vladimír Pata
Bioengineering 2023, 10(12), 1406; https://doi.org/10.3390/bioengineering10121406 - 9 Dec 2023
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Abstract
In this study, the surface laser treatment of a new type of dental biomaterial, a Ti-graphite composite, prepared by low-temperature powder metallurgy, was investigated. Different levels of output laser power and the scanning speed of the fiber nanosecond laser with a wavelength of [...] Read more.
In this study, the surface laser treatment of a new type of dental biomaterial, a Ti-graphite composite, prepared by low-temperature powder metallurgy, was investigated. Different levels of output laser power and the scanning speed of the fiber nanosecond laser with a wavelength of 1064 nm and argon as a shielding gas were used in this experiment. The surface integrity of the machined surfaces was evaluated to identify the potential for the dental implant’s early osseointegration process, including surface roughness parameter documentation by contact and non-contact methods, surface morphology assessment by scanning electron microscopy, and surface wettability estimation using the sessile drop technique. The obtained results showed that the surface roughness parameters attributed to high osseointegration relevance (Rsk, Rku, and Rsm) were not significantly influenced by laser power, and on the other hand, the scanning speed seems to have the most prevalent effect on surface roughness when exhibiting statistical differences in all evaluated profile roughness parameters except Rvk. The obtained laser-modified surfaces were hydrophilic, with a contact angle in the range of 62.3° to 83.2°. Full article
(This article belongs to the Special Issue Recent Prospects on Functional Biomaterials)
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Review

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19 pages, 1476 KiB  
Review
Recent Advances in Magnesium–Magnesium Oxide Nanoparticle Composites for Biomedical Applications
by Abbas Saberi, Madalina Simona Baltatu and Petrica Vizureanu
Bioengineering 2024, 11(5), 508; https://doi.org/10.3390/bioengineering11050508 - 17 May 2024
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Abstract
Magnesium (Mg) is considered an attractive option for orthopedic applications due to its density and elastic modulus close to the natural bone of the body, as well as biodegradability and good tensile strength. However, it faces serious challenges, including a high degradation rate [...] Read more.
Magnesium (Mg) is considered an attractive option for orthopedic applications due to its density and elastic modulus close to the natural bone of the body, as well as biodegradability and good tensile strength. However, it faces serious challenges, including a high degradation rate and, as a result, a loss of mechanical properties during long periods of exposure to the biological environment. Also, among its other weaknesses, it can be mentioned that it does not deal with bacterial biofilms. It has been found that making composites by synergizing its various components can be an efficient way to improve its properties. Among metal oxide nanoparticles, magnesium oxide nanoparticles (MgO NPs) have distinct physicochemical and biological properties, including biocompatibility, biodegradability, high bioactivity, significant antibacterial properties, and good mechanical properties, which make it a good choice as a reinforcement in composites. However, the lack of comprehensive understanding of the effectiveness of Mg NPs as Mg matrix reinforcements in mechanical, corrosion, and biological fields is considered a challenge in their application. While introducing the role of MgO NPs in medical fields, this article summarizes the most important results of recent research on the mechanical, corrosion, and biological performance of Mg/MgO composites. Full article
(This article belongs to the Special Issue Recent Prospects on Functional Biomaterials)
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Other

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10 pages, 927 KiB  
Brief Report
Evaluating Hydroxyapatite, Gold Nanoparticles, and Graphene-Copper as Bimodal Agents for X-ray and Computed Tomography
by Bruno Pugliese Pereira, Claudia Antoine, Aline Oliveira da Silva de Barros, Leonardo de Castro Pacífico, Martha Sahylí Ortega Pijeira, Alexandre Malta Rossi, Eduardo Ricci-Junior, Luciana Magalhães Rebelo Alencar and Ralph Santos-Oliveira
Bioengineering 2023, 10(2), 238; https://doi.org/10.3390/bioengineering10020238 - 10 Feb 2023
Cited by 1 | Viewed by 1474
Abstract
A global need exists for new and more effective contrast agents for computed tomography and traditional X-ray modalities. Among the few options available nowadays, limitations imposed by industrial production, performance, and efficacy restrict the use and reduce the potential of both imaging techniques. [...] Read more.
A global need exists for new and more effective contrast agents for computed tomography and traditional X-ray modalities. Among the few options available nowadays, limitations imposed by industrial production, performance, and efficacy restrict the use and reduce the potential of both imaging techniques. The use of nanomaterials as new contrast agents for X-ray and computed tomography is an innovative and viable way to increase the options and enhance performance. In this study, we evaluated eight nanomaterials: hydroxyapatite doped with zinc (Zn-HA 10%); hydroxyapatite doped with strontium (Sr-HA 10%); hydroxyapatite without thermal treatment (HA 282 STT); thermally treated hydroxyapatite (HA 212 500 °C and HA 01.256 CTT 1000 °C); hydroxyapatite microspheres (HA microspheres); gold nanoparticles (AuNP); and graphene oxide doped with copper (Cu-GO). The results showed that for both imaging modalities; HA microspheres were the best option, followed by hydroxyapatite thermally treated at 1000 °C. The nanomaterials with the worst results were hydroxyapatite doped with zinc (Zn-HA 10%), and hydroxyapatite doped with strontium (Sr-HA 10%). Our data demonstrated the potential of using nanomaterials, especially HA microspheres, and hydroxyapatite with thermal treatment (HA 01.256 CTT 1000 °C) as contrast agents for X-ray and computed tomography. Full article
(This article belongs to the Special Issue Recent Prospects on Functional Biomaterials)
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