Emerging Topics in Precision Medicine: Non-invasive Innovations Shaping Cancer and Immunotherapy Progress

Dear Colleagues,

Immunotherapy, which harnesses the power of immune cells, holds promise in enhancing clinical outcomes, yet is challenged by cancer heterogeneity, variable therapy response, and the development of resistance. Despite several advanced clinical approaches, cancer remains the second-most deadly disease in the world. Therefore, comprehending cancer heterogeneity and immunotherapy response is crucial to optimize personalized therapeutic interventions based on individual tumors. With the integration of big data in medical applications, the incorporation of diverse biomedical data, ranging from molecular to imaging, provides a high-dimensional visualization of cancer behavior. This enables cancer stratification, diagnosis, and therapy management. Thus, the utilization of multimodal data fusion will open avenues for the development of advanced non-invasive investigations, addressing the challenges of cancer intricacies and enhancing the precision of personalized treatment strategies.

The topic welcomes reviews and research articles in computational non-invasive approaches including, but not limited to, radiomics, radiogenomics, computational models, and artificial intelligence methods. 

Dr. Rada Amin
Dr. Bhanwar Lal Puniya
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.