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Novel Applications of Organic Bioelectronics

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: closed (28 February 2018) | Viewed by 27526

Special Issue Editors


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Guest Editor
Chemistry Department, University Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS 15 rue J-A de Baïf, CEDEX 13, 75205 Paris, France
Interests: bioelectrochemistry; biosensors; bioelectronics; transistor; nanomaterials
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Co-Guest Editor
Université Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, 75205 Paris, CEDEX 13, France
Interests: organic electronics; printed electronics; OTFTs; (bio)chemical sensors

Special Issue Information

Dear Colleagues,

More than fifty years have passed since the discovery of high conductivity in polyacetylene, an event that is traditionally considered as the starting point of Organic Electronics. Nowadays, organic electronic devices are ubiquitous and represent a scientific and technological field that is constantly expanding. Particularly promising, in terms of potential future applications, is the field of Organic Bioelectronics, which constitutes a bridge between biological systems and human-made organic electronic devices. Thanks to their unique ability to interact with biomolecules and cells, organic materials are being actively investigated for a wide variety of applications where they can be used for detection purposes but also in a more active way to control and tune the properties of living cells and tissues.

It is our honour as Guest Editors to assemble this Special Issue of Applied Sciences, devoted entirely to Organic Bioelectronics. We are extremely grateful to the authors who contributed to its creation by submitting reports on their excellent work. We feel sure that the readers will be pleased to discover the latest advances in a field which is expected to play a major role in our lives in the near future.

Prof. Benoît Piro
Dr. Giorgio Mattana
Guest Editors

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Keywords

  • Organic bioelectronics

  • Organic electronics sensors

  • (Bio)chemical sensors

  • OTFT

  • Conducting polymer

  • Immunoassays

  • Nanomedicine

  • Cell growth

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Published Papers (2 papers)

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Review

33 pages, 6085 KiB  
Review
Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media
by Benoît Piro, Giorgio Mattana, Samia Zrig, Guillaume Anquetin, Nicolas Battaglini, Dany Capitao, Antoine Maurin and Steeve Reisberg
Appl. Sci. 2018, 8(6), 928; https://doi.org/10.3390/app8060928 - 4 Jun 2018
Cited by 34 | Viewed by 12303
Abstract
This review first recalls the basic functioning principles of organic electrochemical transistors (OECTs) then focuses on the transduction mechanisms applicable to OECTs. Materials constituting the active semiconducting part are reviewed, from the historical conducting polymers (polyaniline, polypyrrole) to the actual gold standard, poly-3,4-ethylenedioxythiophene: [...] Read more.
This review first recalls the basic functioning principles of organic electrochemical transistors (OECTs) then focuses on the transduction mechanisms applicable to OECTs. Materials constituting the active semiconducting part are reviewed, from the historical conducting polymers (polyaniline, polypyrrole) to the actual gold standard, poly-3,4-ethylenedioxythiophene: polystyrene sulfonic acid (PEDOT:PSS), as well as the methods used to fabricate these transistors. The review then focuses on applications of OECTs for the detection of small molecules and more particularly of metabolites, with a distinction between enzymatic and non-enzymatic transduction pathways. Finally, the few patents registered on the topic of OECT-based biosensors are reviewed, and new tracks of improvement are proposed. Full article
(This article belongs to the Special Issue Novel Applications of Organic Bioelectronics)
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27 pages, 7406 KiB  
Review
Flexible and Organic Neural Interfaces: A Review
by Nicolò Lago and Andrea Cester
Appl. Sci. 2017, 7(12), 1292; https://doi.org/10.3390/app7121292 - 12 Dec 2017
Cited by 44 | Viewed by 13975
Abstract
Neural interfaces are a fundamental tool to interact with neurons and to study neural networks by transducing cellular signals into electronics signals and vice versa. State-of-the-art technologies allow both in vivo and in vitro recording of neural activity. However, they are mainly made [...] Read more.
Neural interfaces are a fundamental tool to interact with neurons and to study neural networks by transducing cellular signals into electronics signals and vice versa. State-of-the-art technologies allow both in vivo and in vitro recording of neural activity. However, they are mainly made of stiff inorganic materials that can limit the long-term stability of the implant due to infection and/or glial scars formation. In the last decade, organic electronics is digging its way in the field of bioelectronics and researchers started to develop neural interfaces based on organic semiconductors, creating more flexible and conformable neural interfaces that can be intrinsically biocompatible. In this manuscript, we are going to review the latest achievements in flexible and organic neural interfaces for the recording of neuronal activity. Full article
(This article belongs to the Special Issue Novel Applications of Organic Bioelectronics)
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