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Appl. Sci. 2018, 8(6), 928; https://doi.org/10.3390/app8060928

Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media

1
Université Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, 75205 Paris CEDEX 13, France
2
ValoTec, 1 Mail du Professeur Georges Mathé, 94800 Villejuif, France
*
Author to whom correspondence should be addressed.
Received: 9 May 2018 / Revised: 1 June 2018 / Accepted: 1 June 2018 / Published: 4 June 2018
(This article belongs to the Special Issue Novel Applications of Organic Bioelectronics)
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Abstract

This review first recalls the basic functioning principles of organic electrochemical transistors (OECTs) then focuses on the transduction mechanisms applicable to OECTs. Materials constituting the active semiconducting part are reviewed, from the historical conducting polymers (polyaniline, polypyrrole) to the actual gold standard, poly-3,4-ethylenedioxythiophene: polystyrene sulfonic acid (PEDOT:PSS), as well as the methods used to fabricate these transistors. The review then focuses on applications of OECTs for the detection of small molecules and more particularly of metabolites, with a distinction between enzymatic and non-enzymatic transduction pathways. Finally, the few patents registered on the topic of OECT-based biosensors are reviewed, and new tracks of improvement are proposed. View Full-Text
Keywords: organic electrochemical transistors; OECT; biosensors; metabolites; organic semiconductors; industrial applications; patents organic electrochemical transistors; OECT; biosensors; metabolites; organic semiconductors; industrial applications; patents
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Piro, B.; Mattana, G.; Zrig, S.; Anquetin, G.; Battaglini, N.; Capitao, D.; Maurin, A.; Reisberg, S. Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media. Appl. Sci. 2018, 8, 928.

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