Vitamin C: Current Concepts in Human Physiology
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (31 January 2018) | Viewed by 110597
Special Issue Editors
Interests: sepsis; acute lung injury; hemorrhagic shock and trauma; transplantation medicine; hemostasis and thrombosis; ischemia-reperfusion; inflammation; wound healing; coagulation; gene regulation; nitric oxide; molecular biology; cell biology
Interests: vitamin C; intake recommendations; respiratory infections; immune function; diabetes; metabolic health; mood; cognitive health; health-related quality of life
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Vitamin C is synthesized by almost all animals. However, for humans, it is a vitamin that needs constant replenishment in the diet. While its role as an anti-oxidant and for preventing scurvy have been known for a long time, novel functions and unrecognized associations continue to be identified for this enigmatic molecule. In the past decade, new details have emerged regarding differences in its uptake by oral and intravenous modes. While vitamin C deficiency remains largely unknown and poorly addressed in many segments of the population, novel pharmacological roles for high dose intravenous vitamin C in many disease states have now been postulated and investigated. This has shifted its role in health and disease from the long perceived notion as merely an anti-oxidant, to a pleiotropic molecule with a broad anti-inflammatory, epigenetic and anti-cancer profile.
This Special Issue will publish original research papers and reviews on vitamin C metabolism and function that relate to the following topics: Unrecognized nutritional deficiency in disease; understanding its role in the modulation of inflammation and immunity; therapeutic applications of pharmacological ascorbate in disease; epigenetic modulation of disease by vitamin C; and the emerging role of vitamin C as a pleiotropic modulator of critical care illness and cancer.
Prof. Dr. Ramesh Natarajan
Dr. Anitra Carr
Guest Editors
Manuscript Submission Information
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Keywords
- Bioavailability
- Gene regulation
- Inflammation
- Critical care illness
- Cardiovascular diseases
- Epigenetics
- Metabolism
- Cancer
- Cognition
- Quality of life
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