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Special Issue "Oxidative Stress and Cardiovascular Disease"
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (30 September 2018).
Interests: oxidative stress; platelet function; cardiovascular disease; development of new markers of oxidative stress; nutraceutical in particular evaluation of antioxidant activities of natural products and food in patients and in healthy subjects
Special Issues and Collections in MDPI journals
The pathogenetic and prognostic roles of cardiovascular risk factors, such as hypercholesterolemia, arterial hypertension, diabetes mellitus, obesity, atrial fibrillation, advanced age, and smoking habits on cardiovascular (CV) outcomes are well established. Nevertheless, behind the classic mechanisms through which they contribute to accelerated cardiovascular events, in particular atherosclerosis, many studies have demonstrated that all these conditions are characterized by a common feature: Enhanced oxidative stress. When there is an imbalance between the elevated production of reactive oxygen species (ROS)/reactive nitrogen species (RNS) and missing antioxidants, there is an enhanced oxidative stress, leading to oxidative modifications of proteins, lipids, and DNA. The “oxidative stress theory” of cardiovascular disease is based on the assumption that the initial phase of disease is sustained by the increase in oxidative stress, dependent on ROS, produced both by blood cells and by resident cells of the arterial wall. Further investigation into this subject will provide renewed insight on the implication of oxidative stress in cardiovascular disease.
We are interested in original research articles, as well as review articles, that explore the mechanism insight and development of novel oxidative stress biomarkers, the development of strategies to treat these pathologies and the evaluation of outcomes, in particular using antioxidants drugs.
Potential topics include, but are not limited to:
- Recent advances on the impact of oxidative stress in cardiovascular disease and atherosclerosis;
- Redox signaling in the development of cardiac hypertrophy, remodeling and arrhythmias
- Advances in epigenetics of CV diseases and atherosclerosis
- Novel risk factors in cardiovascular diseases and latest advances in clinical evaluation
- Elucidating the role of Oxidative Stress in Cardiovascular Inflammation
- New molecules and biochemical pathways for the development of atherosclerotic plaque
- microRNAs biology, their role in patho-physiology and therapy
Dr. Cristina Nocella
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Oxidative stress
- Cardiovascular disease
- NADPH oxidase
- Platelet function
- Endothelial dysfunction