Oxidative Stress in Hepatic Injury
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (20 March 2023) | Viewed by 49498
Special Issue Editors
Interests: liver immunology; alcoholic liver diseases; non-alcoholic steatohepatitis; epigenetic regulator; metabolic syndrome; hepatocellular carcinoma
Interests: inflammation; pancreatitis; immunology; liver injury
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Oxidative stress plays critical roles in various liver diseases including alcoholic liver diseases (ALD), non-alcoholic steatohepatitis (NASH), viral infection of hepatitis (HBV or HCV), and drug-induced liver disease. During oxidative stress in liver injury, free radicals such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) are mostly generated at the initial stage, then they can rapidly react with hepatocyte’s protein, lipids, and DNA. These conditions directly disrupt the cellular and molecular level of the structure–function relationship of the hepatocyte in different sites; however, the pathophysiological mechanisms remain unclear, and there no effective therapeutics are accessible.
We invite you to submit your recent research findings or a review article to this Special Issue, which will bring together current research concerning oxidative stress in the liver and potent antioxidant effects of therapeutics, including drug candidates or target molecules. This Special Issue invites in vitro experiments, in vivo experiments using preclinical animal models, and clinical trials. Studies relating to any of the following topics are welcome: Oxidative stress-related target molecules; regulation of redox status of liver injury; possible drug candidates of antioxidant effects of drugs during liver injury; molecular levels of oxidative stress features on various hepatic tissue oxidations; metabolism and oxidative stress during chronic liver injury; epigenetic regular and oxidative stress in liver injury; crosstalk of oxidative hepatic oxidation and hepatic inflammation in acute/chronic liver injury; comparison analysis of drug-induced liver tissue oxidation; and endoplasmic stress and oxidative stress in liver tissue.
We sincerely anticipate your valuable contribution.
Dr. Hyeong-Geug Kim
Dr. Gi-Sang Bae
Guest Editors
Manuscript Submission Information
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Keywords
- Hepatic tissue oxidation
- Redox homeostasis
- Free radicals
- Alcoholic liver injury
- Non-alcoholic fatty liver diseases
- Epigenetic regulator
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