Special Issue "Strategies against Bacterial Biofilm Formation"

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editors

Dr. Fany Reffuveille
E-Mail Website
Guest Editor
Université de Reims Champagne-Ardenne, EA4691 BIOS lab, Reims, France
Interests: biofilm; bone and joint infections; antibiofilm; internalization
Special Issues and Collections in MDPI journals
Dr. Marius Colin
E-Mail Website
Guest Editor
Université de Reims Champagne-Ardenne, EA4691 BIOS lab, Reims, France
Interests: Antibacterial strategies; Biofilm; Bone and Joint infections; antibiofilm

Special Issue Information

Dear Colleagues,

Biofilm is a mysterious multicellular bacterial form of life that has not revealed all its secrets.

It represents an adaptive and quite common bacterial response to several stress factors, which confer an important protection to bacteria. Biofilm formation starts with bacterial adhesion on a surface, further reinforced by matrix synthesis to finally reach a complex structure. Biological tissues such as bones, lungs or even implanted devices are frequently the siege of biofilm colonization. Furthermore, biofilm implication in numerous diseases is regularly reevaluated upwards. As biofilms are tolerant to any known antibiotics, they represent a major issue for public health. Thus, there is an urgent need to develop adapted strategies to inhibit, perturb or destruct this structure to efficiently fight against biofilm infection.

This Special Issue seeks manuscripts that focus on the development of antibiofilm strategies: chemical or natural compounds, physical techniques, functionalized materials or other innovative antibiofilm processes are welcomed.

Potential topics include but are not limited to:

  • Biofilms mechanisms;
  • Identification of bacterial targets to fight against biofilm;
  • Antibiofilm molecules;
  • Synergy of antimicrobial and antibiofilm molecules;
  • In vitro or in vivo biofilm models development.

Dr. Fany Reffuveille
Dr. Marius Colin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • biofilm
  • matrix
  • antiadhesive
  • antibiofilm
  • antibiotic tolerance

Published Papers

This special issue is now open for submission.
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