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Antibiotics
Special Issues
Treatment of Mastitis in Dairy Cattle, 2nd Edition
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Treatment of Mastitis in Dairy Cattle, 2nd Edition

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2961

Special Issue Editors

Prof. Dr. Volker Krömker

E-Mail Website
Guest Editor
Section for Production, Nutrition and Health, University of Copenhagen, Copenhagen, Denmark
Interests: antibiotic treatment of cattle; mastitis treatment
Special Issues, Collections and Topics in MDPI journals
Dr. Paolo Moroni

E-Mail Website
Guest Editor
1. QMPS, Cornell University, Ithaca, NY, USA
2. Dipartimento di Medicina Veterinaria e Scienze Animali - DIVAS, Università degli Studi di Milano, Via dell'Universita', 26900 Lodi (LO), Italy
Interests: infectious disease; cow; veterinary

Special Issue Information

Dear Colleagues,

Mastitis is the disease for which approximately 75% of antibiotic doses are used in dairy cows. Mastitis treatment is now changing significantly in many countries. The goal of avoiding antibiotic resistance and the optimization of therapy, considering antibiotic minimization, efficacy optimization, and user interests, lead to differentiated and practical therapy concepts. Research papers addressing diagnostic, therapeutic, epidemiological, psychological, and legal aspects are welcome.

Prof. Dr. Volker Krömker
Dr. Paolo Moroni
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • targeted mastitis treatment
  • antimicrobial resistance
  • therapy-decisive diagnostics
  • cure rates
  • compliance
  • user questions

Published Papers (2 papers)

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Research

17 pages, 2390 KiB  
Article
Effect of the Selective Dry Cow Therapy on Udder Health and Milk Microbiota
by Laura Filippone Pavesi, Claudia Pollera, Giulia Sala, Paola Cremonesi, Valentina Monistero, Filippo Biscarini and Valerio Bronzo
Antibiotics 2023, 12(8), 1259; https://doi.org/10.3390/antibiotics12081259 - 31 Jul 2023
Viewed by 1269
Abstract
Recently, the use of antimicrobials on dairy farms has been significantly limited from both the legislative and consumer points of view. This study aims to check the efficacy of selective dry cow therapy (SDCT) versus blanket dry cow therapy (BDCT) on bovine udder [...] Read more.
Recently, the use of antimicrobials on dairy farms has been significantly limited from both the legislative and consumer points of view. This study aims to check the efficacy of selective dry cow therapy (SDCT) versus blanket dry cow therapy (BDCT) on bovine udder in healthy animals. SDTC is when an antibiotic is administered only to infected cows, compared with BDCT, where all cows receive an antimicrobial, regardless of their infection status. The milk samples were collected from enrolled Holstein Friesian cows 7 days before dry-off (T0) and 10 days after calving (T1) to assess somatic cell count (SCC), intramammary infections (IMIs), and milk microbiota variation. After pre-drying sampling, cows are randomly assigned to the following treatments: internal teat sealant alone (ITS; 24 cows), which is a treatment in a cow that does not receive antibiotics in SDTC, or in combination with intramammary antibiotic treatment (A+ITS; 22 cows). Non-statistically significant results are found between the two treatment groups at T1 for SCC, milk yield, and alpha diversity in milk microbiota. A statistically (p < 0.033) T1 IMI decrease is reported in the A+ITS group, and a significant beta diversity analysis is shown between the two timepoints (p = 0.009). This study confirms the possibility of selective drying without new IMI risk or increased SCC at calving, considering healthy cows without contagious infections and SCC values >200,000 cells/mL in the previous lactation. Full article
(This article belongs to the Special Issue Treatment of Mastitis in Dairy Cattle, 2nd Edition)
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14 pages, 288 KiB  
Article
Effect of Antibiotic Compared to Non-Antibiotic Dry Cow Treatment on the Bacteriological Cure of Intramammary Infections during the Dry Period—A Retrospective Cross-Sectional Study
by Stephanie Müller, Julia Nitz, Anne Tellen, Doris Klocke and Volker Krömker
Antibiotics 2023, 12(3), 429; https://doi.org/10.3390/antibiotics12030429 - 21 Feb 2023
Cited by 3 | Viewed by 1310
Abstract
Antimicrobials are widely used to cure intramammary infections (IMI) in dairy cows during the dry period (DP). Nevertheless, the IMI cure is influenced by many factors and not all quarters benefit from antimicrobial dry cow treatment (DCT). To evaluate the true effect of [...] Read more.
Antimicrobials are widely used to cure intramammary infections (IMI) in dairy cows during the dry period (DP). Nevertheless, the IMI cure is influenced by many factors and not all quarters benefit from antimicrobial dry cow treatment (DCT). To evaluate the true effect of antibiotic DCT compared to self-cure and the role of causative pathogens on the IMI cure, a retrospective cross-sectional study was performed. The analysis included 2987 quarters infected at dry-off (DO). Information on DCT, causative pathogens, somatic cell count, milk yield, amount of lactation, Body Condition Score, and season and year of DO were combined into categorical variables. A generalized linear mixed model with a random cow, farm and year effect and the binary outcome of bacteriological cure of IMI during the DP was conducted. In the final model, a significant effect (p < 0.05) on DP cure was seen for the DO season and the category of causative pathogens (categories being: Staphylococcus aureus, non-aureus staphylococci, streptococci, coliforms, ‘other Gram-negative bacteria’, ‘other Gram positive bacteria’, non-bacterial infections and mixed infections), while antibiotic DCT (vs. non-antibiotic DCT) only showed a significant effect in combination with the pathogen categories streptococci and ‘other Gram-positive bacteria’. Full article
(This article belongs to the Special Issue Treatment of Mastitis in Dairy Cattle, 2nd Edition)
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