Diseases of Marine Mammals: Prevention, Control and Beyond

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Mammals".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 239

Special Issue Editor


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Guest Editor
College of Veterinary Medicine, Western University, Pomona, CA, USA
Interests: One Health; ocean health; marine mammal pathology; veterinary pathology

Special Issue Information

Dear Colleagues,

One Health is a paradigm in medicine where ocean health is one of the foundational strategies, not only in the conservation efforts of protecting the marine ecosystem, but where marine life takes a role as sentinels for human health. Marine mammals, such as cetaceans, pinnipeds, and sirenians, face a variety of emerging and re-emerging diseases that pose significant threats to their health, survival, and conservation efforts. These diseases, ranging from infectious to environmental pollutants, present widespread ecological and economic impact. Understanding the dynamics of marine mammal health is critical not only for species survival, but also for the preservation of healthy marine ecosystems and consequently aquatic animal and human health. Recent studies have highlighted the impacts of climate change, habitat degradation, and anthropogenic activities, which exacerbate disease susceptibility and hinder effective disease prevention and control strategies. Despite significant progress in understanding the etiology and pathology of marine mammal diseases, progress must still be made in terms of establishing robust diagnostic tools, effective preventive measures, and cross-disciplinary management approaches.

The goal of this Special Issue is to compile recent advances in the study of marine mammal diseases, focusing on prevention, control, and innovative strategies for diagnostics, control and long-term management. Contributions will highlight novel diagnostic methods, therapeutic interventions, and ecological approaches to minimize disease risks. By bridging gaps between veterinary medicine, pathology, marine biology, and environmental science, this Special Issue aims to provide a comprehensive resource for researchers, conservationists, and policymakers dedicated to safeguarding ocean health, marine mammal health and biodiversity.

Dr. Suzana Tkalcic
Guest Editor

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Keywords

  • marine mammals
  • ocean health
  • climate change
  • anthropogenic impacts
  • conservation
  • disease prevention and control
  • diagnostics
  • health management

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Published Papers (1 paper)

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Research

12 pages, 1845 KiB  
Article
Serum Concentrations of Imidazole Dipeptides and Serum Amyloid A in a Bottlenose Dolphin (Tursiops truncatus) with Rhabdomyolysis: Potential Biomarkers for Muscular Damage
by Nanami Arakawa, Mika Otsuka, Takahisa Hamano, Momochika Kumagai, Sanae Kato, Takuya Hirai, Akira Yabuki and Osamu Yamato
Animals 2025, 15(13), 1950; https://doi.org/10.3390/ani15131950 - 2 Jul 2025
Abstract
Imidazole dipeptides (IDPs), including anserine, carnosine, and balenine, are predominantly found in the skeletal muscles of vertebrates. Balenine is the major IDP in cetaceans. Serum amyloid A (SAA) is an acute phase protein released in response to damage or injury in various tissues, [...] Read more.
Imidazole dipeptides (IDPs), including anserine, carnosine, and balenine, are predominantly found in the skeletal muscles of vertebrates. Balenine is the major IDP in cetaceans. Serum amyloid A (SAA) is an acute phase protein released in response to damage or injury in various tissues, including skeletal muscles. A captive bottlenose dolphin (Tursiops truncatus) died due to rhabdomyolysis and subsequent acute kidney injury that probably originated from accidental muscle trauma. In this study, concentrations of IDPs and SAA were measured using stored serum collected from the affected dolphin with intermittent continuous damage of skeletal muscles to demonstrate the pathological relevance of these parameters and their usefulness as biomarkers for muscle damage in dolphins. The IDP concentration was measured using the high-performance liquid chromatography-ultraviolet method. The SAA concentration was measured using an enzyme-linked immunosorbent assay (ELISA) specific to dolphin SAA and a latex turbidimetric immunoassay (LTI) specific to human SAA. Herein, the IDP concentration was altered similarly to serum muscular enzymes, including creatinine kinase (CK) and aspartate aminotransferase (AST). However, IDP concentrations were elevated one day earlier than CK and AST levels at disease onset. Furthermore, IDP concentrations were similarly altered when assessed using both ELISA- and LTI-SAAs, and the change in IDP concentration coincided with that in LTI-SAA based on the statistical analysis. These data suggest that IDP concentration could detect muscle damage and injury, including necrosis and inflammation, in dolphins. Full article
(This article belongs to the Special Issue Diseases of Marine Mammals: Prevention, Control and Beyond)
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