Neuroendocrine Responses to Environmental Challenges: Exploring Brain–Stress Interactions in Aquatic Species

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Aquatic Animals".

Deadline for manuscript submissions: 15 March 2026 | Viewed by 1176

Special Issue Editor


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Hochschule für Agrar-, Forst- und Lebensmittelwissenschaften (HAFL), Applied University Berne (BFH), 3052 Zollikofen, Switzerland
Interests: fish; brain; stress; neuroendocrine
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Special Issue Information

Dear Colleagues,

The realm of neuroendocrinology stands at the forefront of understanding how aquatic species navigate environmental challenges. As we delve deeper into this intricate field, a burgeoning emphasis on elucidating brain–stress interactions has emerged. Aquatic species are exposed to a huge variety of different stressors, both environmental and anthropogenic. However, our understanding of the exact mechanisms that lead to the appropriate responses of aquatic species to these stressors is scarce. Hence, neuroendocrine regulations at the brain level, by means of neurotransmitter and gene expression studies, need to be studied in more detail.

Beyond conventional macroscopic inquiries into brain anatomy, a surge of research is also delving into cellular-level investigations, particularly through in vitro studies employing innovative cell culture techniques. These endeavors have unveiled profound insights into the morphological and functional alterations of nerve cells in response to various stressors. For instance, investigations into cell aging have shed light on the dynamic changes that cells undergo over time, while explorations into the neuroendocrine responses of diverse aquatic species have uncovered enzymatic alterations with far-reaching implications for cellular DNA functionality.

In light of these groundbreaking advancements, we invite submissions encompassing elucidating brain and nerve cell morphological adaptations amidst diverse stress conditions in aquatic species. Through this Special Issue, we will foster a comprehensive understanding of neuroendocrine responses to environmental challenges, thereby paving the way for innovative approaches in aquatic species conservation and neuroscientific research.

Dr. Constanze Pietsch
Guest Editor

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Keywords

  • neuroendocrinology
  • aquatic species
  • brain–stress interactions
  • environmental adaptation

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Published Papers (1 paper)

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Research

17 pages, 3687 KiB  
Article
Acute Stress Effects over Time on the Gene Expression and Neurotransmitter Patterns in the Carp (Cyprinus carpio) Brain
by Constanze Pietsch, Paulina Pawlak and Jonathan Konrad
Animals 2024, 14(23), 3413; https://doi.org/10.3390/ani14233413 - 26 Nov 2024
Cited by 1 | Viewed by 804
Abstract
Changes in gene expression in carps’ brains over time following acute stressors has not been studied in detail so far. Consequently, a stress trial with juvenile common carp was conducted to investigate transcriptomic differences in four brain parts in response to acute negative [...] Read more.
Changes in gene expression in carps’ brains over time following acute stressors has not been studied in detail so far. Consequently, a stress trial with juvenile common carp was conducted to investigate transcriptomic differences in four brain parts in response to acute negative stressors and feed reward, focusing on appetite-related genes, serotonergic and dopaminergic pathways, and other involved systems, at 30, 60, and 90 min after treatments. The treatments showed pronounced effects on the gene expression patterns across brain parts compared to control fish. Notably, npy expression increased in the telencephalon following negative stressors and feed reward, suggesting a stress-coping mechanism by promoting food intake. Unlike zebrafish, cart expression in carp showed varying responses, indicating species-specific regulation of appetite and stress. Serotonergic and dopaminergic pathways were also affected, with alterations in the respective receptors’ expression, confirming their roles in stress and reward processing. Additionally, this study highlights the involvement of the opioid- and gamma-aminobutyric acid systems in stress and feeding regulation across brain parts. Furthermore, principal component analyses revealed that neurotransmitter levels in the different brain parts contribute to the explained variance. These findings deepen our understanding of how different fish species react to acute stress and rewards. Full article
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