Amino Acids Nutrition and Health in Farm Animals

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Nutrition".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 430

Special Issue Editor


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Guest Editor
State Key Laboratory of Animal Nutrition and Feeding, China Agricultural University, Beijing 100193, China
Interests: animal nutrition physiology; regulation of nutrition and metabolism; the interaction between intestinal microorganisms and intestinal epithelial cells; immunity and intestinal health

Special Issue Information

Dear Colleagues,

Protein nutrition is critical for the health of farm animals due to multiple functional roles in cell proliferation, intestinal health, and the maintenance of biological processes, such as immune response, embryo attachment and implantation, fetal survival and development, disease recovery, and the production of meat, milk, and eggs. It is generally believed that peptides and amino acids are the predominant mediators that confer to these functions in humans and animals.

Original papers, including research papers and review papers related to protein, peptide, amino acids, and the nutrition and health of farm animals, are welcome to be submitted to this Special Issue. All submitted papers will be reviewed according to the Animals journal guidelines.

Prof. Dr. Zhenlong Wu
Guest Editor

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Keywords

  • protein
  • peptide
  • amino acids
  • intestinal health
  • immune response
  • oxidative stress
  • feeding and management
  • metabolism

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Published Papers (1 paper)

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Research

14 pages, 8085 KiB  
Article
Methionine Antagonizes Liver and Kidney Antioxidant Function Damage in Heat-Stressed Rex Rabbits
by Shu Li, Xiaosong Wang, Gongyan Liu, Lei Liu and Fuchang Li
Animals 2025, 15(8), 1148; https://doi.org/10.3390/ani15081148 - 16 Apr 2025
Viewed by 284
Abstract
Heat stress triggers systemic oxidative stress that compromises physiological homeostasis. This study evaluated methionine’s effects on hepatic and renal antioxidant capacity in heat-stressed Rex rabbits. Rabbits were divided into five groups (30 replicates/group): control (20–25 °C, basal diet), heat stress (HS, 30–34 °C, [...] Read more.
Heat stress triggers systemic oxidative stress that compromises physiological homeostasis. This study evaluated methionine’s effects on hepatic and renal antioxidant capacity in heat-stressed Rex rabbits. Rabbits were divided into five groups (30 replicates/group): control (20–25 °C, basal diet), heat stress (HS, 30–34 °C, basal diet), and HS +0.15%, 0.3%, or 0.45% methionine-supplemented groups. After 21 days, serum, skin, liver, and kidney samples were analyzed for biochemical parameters, oxidative stress markers, and gene expression. Results showed that 0.15–0.3% methionine supplementation under heat stress increased methionine apparent digestibility and suppressed amino acid catabolism; decreased serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels; reduced skin malondialdehyde (MDA) and elevated (MSRA) activity; attenuated hepatic central venous congestion and renal tubular vacuolization; enhanced hepatic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activities (0.3% group); and modulated antioxidant gene expression via Nrf2/HO-1 and Nrf2/NQO1 pathways. Pathological analysis confirmed reduced fibrosis and cellular damage in liver/kidney tissues. Optimal methionine supplementation (0.3%) effectively mitigated heat-induced oxidative organ damage by enhancing endogenous antioxidant defenses and regulating redox-sensitive signaling pathways. These findings provide a nutritional strategy for alleviating heat stress-related metabolic disorders in rabbits. Full article
(This article belongs to the Special Issue Amino Acids Nutrition and Health in Farm Animals)
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