Research in the Mediterranean and Neighboring Regions for COVID-19: Facts Scenarios and Growing Awareness

A special issue of Acta Microbiologica Hellenica (ISSN 2813-9054).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1992

Special Issue Editors


E-Mail Website
Guest Editor
European Health and Medical Consultants, Woluwedal 12, 1932 Brussel, Belgium
Interests: laboratory medicine; molecular diagnosis; gender medicine; EU research policies

E-Mail Website
Guest Editor
Laboratory of Hygiene and Environmental Protection, Department of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece
Interests: microbiome; antimicrobials; antibiotics; biofilms
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Public and Community Health, University of West Attica, 11521 Athens, Greece
Interests: epidemiology of chronic diseases; child and maternal health and the development of intervention programs and their prevention

Special Issue Information

Dear Colleagues,

The COVID-19 pandemic spread across the globe, affecting equally the Mediterranean basin and its surrounding countries. The Mediterranean region presents diversity in its economy, culture, civilization, and societal issues. It has historically been the center of world civilization and has been known for its flourishing wealth, empires, wars, and population displacements across the centuries. The Mediterranean Sea is the crossroad of the European, Asian, and African continents and is surrounded by various countries. This region shares a similar climate but diverse cultural and social characteristics and was affected by the COVID-19 pandemic in early 2020. Considering the diversity across this region, the impact of COVID-19 presented similarities and differences among its countries and peoples that represent a challenge in unravelling a series of mysteries related to Sars COV 2. Reputed institutes still invest in Sars COV 2 basic and applied research. Currently, knowledge of the impact of the pandemic in this region remains fragmentary, and research in all fields of COVID-19 study is still ongoing, and, in some instances, left unpublished.

This Special Issue aims to provide an opportunity for researchers to demonstrate their research and shed light on different aspects of the disease in the Mediterranean and its neighboring regions.

We invite researchers to submit their latest research work and share their experience with other fellow researchers. The topics in this Special Issue include, but not limited to, the following:

  • Basic research and disease pathophysiology;
  • Detection methods, vaccination, and immunity;
  • Pharmaceutical treatment and clinical trials;
  • Long COVID-19 disease, incidence, prevalence, and clinical features;
  • Predictive-modeling healthcare data analytics and big data analysis (all fields);
  • Epidemiological modelling, prevention and control, and outbreak emergency management;
  • Risk forecasting, communication, assessment, community impact, awareness, and readiness studies;
  • Public health, environmental policy, and surveillance systems;
  • The impact of COVID-19 on Sustainable Development Goals (SDGs);
  • Cross-border impacts and pan-Mediterranean action prevention models.

Prof. Dr. Ekatherina Charvalos
Prof. Dr. Eugenia Bezirtzoglou
Prof. Dr. Anastasia Barbouni
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Acta Microbiologica Hellenica is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COVID-19
  • detection
  • vaccination
  • immunity
  • prevalence
  • public health

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

10 pages, 2155 KiB  
Article
Genomic and Epidemiological Surveillance of SARS-CoV-2 Epidemic in Northwestern Greece
by Prodromos Sakaloglou, Petros Bozidis, Konstadina Kourou, Charilaos Kostoulas, Athanasia Gouni, Eleni Tsaousi, Despoina Koumpouli, Sofia Argyropoulou, Petros Oikonomidis, Helen Peponi, Ioannis Sarantaenas, Eirini Christaki, Ioannis Georgiou and Konstantina Gartzonika
Acta Microbiol. Hell. 2024, 69(4), 285-294; https://doi.org/10.3390/amh69040026 - 10 Dec 2024
Viewed by 322
Abstract
In early 2020, Greece was affected by the SARS-CoV-2 epidemic, and since then, the continuous emergence of fast-spreading variants has caused surges of new SARS-CoV-2 infections. In this study, we performed genomic, phylogenetic, and epidemiological analyses to investigate the SARS-CoV-2 epidemic in northwestern [...] Read more.
In early 2020, Greece was affected by the SARS-CoV-2 epidemic, and since then, the continuous emergence of fast-spreading variants has caused surges of new SARS-CoV-2 infections. In this study, we performed genomic, phylogenetic, and epidemiological analyses to investigate the SARS-CoV-2 epidemic in northwestern Greece. From March 2020 to February 2022, nasopharyngeal samples obtained from patients suspected to have COVID-19 were tested for SARS-CoV-2 detection. Complete SARS-CoV-2 genomic sequences were generated from selected positive samples. Northwestern Greece experienced four distinct waves of the epidemic following the first wave, which was mainly observed in Attica and other parts of Greece. The positivity index was rising throughout the pandemic waves in several geographical units, with the highest levels recorded in prominent tourist destinations characterized by high agricultural density. The phylogenetic analyses revealed 34 different lineages, with B.1, B.1.1, B.1.1.305, B.1.1.318, B.1.177, B.1.1.7, B.1.617.2, AY.43, and BA.1 being the most prevalent lineages in the region. Although multiple lineages were co-circulating, each pandemic wave was dominated by a different lineage. The SARS-CoV-2 epidemic in northwestern Greece was characterized by the successive introduction of new lineages, resulting in surges of new SARS-CoV-2 infections. Full article
Show Figures

Figure 1

11 pages, 743 KiB  
Article
Clinical and Prognostic Utility of Cycle Threshold (Ct) Value of SARS-CoV-2 in Pediatric Population: Single-Center Experience
by Francesco Gambilonghi, Valeria Fichera, Vincenzo Sortino, Patrizia Grassi, Ausilia Desiree Collotta, Marco Simone Vaccalluzzo, Alfredo Pulvirenti, Silvia Marino, Martino Ruggieri, Salvatore Castiglione and Raffaele Falsaperla
Acta Microbiol. Hell. 2024, 69(4), 274-284; https://doi.org/10.3390/amh69040025 - 28 Nov 2024
Viewed by 213
Abstract
The cycle threshold (Ct) value of PCR, used to detect SARS-CoV-2 viral load, has been associated with disease severity in adults, but few studies have examined these relationships in pediatric patients. The aim of this study was to evaluate the relationship between the [...] Read more.
The cycle threshold (Ct) value of PCR, used to detect SARS-CoV-2 viral load, has been associated with disease severity in adults, but few studies have examined these relationships in pediatric patients. The aim of this study was to evaluate the relationship between the Ct value at hospital admission and the duration of fever, length of hospital stay, and the need for medical interventions in pediatric patients with COVID-19. We conducted a retrospective study of 124 pediatric patients with a positive nasopharyngeal swab for SARS-CoV-2 between April 2020 and March 2022. A negative correlation was observed between the Ct value and the duration of fever (p = 0.012), with a similar trend for length of hospital stay (p = 0.25). A low Ct value was also associated with the development of MIS-C (p = 0.026) and the need for respiratory support and steroid therapy (p = 0.036). The Ct value may be useful in stratifying pediatric patients with COVID-19, helping to predict the duration of fever and hospital stay, as well as the need for medical interventions. Full article
Show Figures

Figure 1

12 pages, 926 KiB  
Article
Urinary Neutrophil Gelatinase-Associated Lipocalin as a Predictor of COVID-19 Mortality in Hospitalized Patients
by Luka Švitek, Mihaela Zlosa, Barbara Grubišić, Kristina Kralik, Nora Perić, Bernarda Berišić, Dubravka Lišnjić and Sanja Mandić
Acta Microbiol. Hell. 2024, 69(4), 224-235; https://doi.org/10.3390/amh69040021 - 17 Oct 2024
Viewed by 664
Abstract
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein secreted by activated neutrophils and certain tissues. The aim of this study was to investigate the prognostic role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in hospitalized COVID-19 patients with regard to mortality. The prospective observational cohort [...] Read more.
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein secreted by activated neutrophils and certain tissues. The aim of this study was to investigate the prognostic role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in hospitalized COVID-19 patients with regard to mortality. The prospective observational cohort study involved 86 hospitalized adult COVID-19 patients. Patients’ urine samples were collected upon admission and 48–72 h after admission. General anamnesis and clinical status information were obtained from medical records. Within 24 h of sample collection, urine aliquots were centrifuged, the supernatant was separated, and samples were frozen at −80 °C until uNGAL concentration measurement, which was performed within two years of sample collection. The patients were categorized into groups based on disease outcome (survived/deceased). Data analysis was performed to identify predictive factors and diagnostic indicators for the unfavorable outcome group using logistic regression and ROC curve methods. Logistic regression associated age, cardiomyopathy, invasive mechanical ventilation, and uNGAL concentration (follow-up sampling) with mortality. ROC analysis identified uNGAL concentration (follow-up sampling) as an indicator of mortality, with a cut-off value of >23.8 ng/mL. This study concludes that there is an association between disease outcome and uNGAL concentration in COVID-19 patients. However, understanding the dynamics of uNGAL concentration during COVID-19 remains limited, which is crucial for its effective clinical application. Full article
Show Figures

Figure 1

Back to TopTop