Research Progress and Application Prospect of Medicinal Plants—Volume II

A special issue of Agronomy (ISSN 2073-4395). This special issue belongs to the section "Horticultural and Floricultural Crops".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 3539

Special Issue Editors


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UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA
Interests: cheminformatics; medicinal chemistry; antiviral research; computational toxicology; natural products
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Special Issue Information

Dear Colleagues,

Natural organisms, especially plants, provide innumerable molecules, phenolic compounds, flavonoids, alkaloids, terpenes, secondary metabolites, with the potential to treat several diseases owing to their beneficial effects on human health, such as their antiviral, antiallergic, antiplatelet, anti-inflammatory, antitumor, antioxidant and antiparasitic activities. The history of oriental and occidental civilizations is very rich in examples of the utilization of natural products in medicine and health care. The complexity, chemical diversity and biological properties of natural products have always fascinated people, and in the last 200 years, this has led to the discovery of important novel drugs. The utilization of natural products has been the subject of increasing interest in phytochemistry, biochemistry and other fields of research at the chemistry–biology–ecosystem interface. Many studies report different approaches to employing these compounds in drug discovery, comprising synthesis, semi-synthesis, the search for novel targets, and the evaluation of biological activities, and/or theoretical approaches, such as structure-based approaches, SAR, QSAR, docking and cheminformatics methods.

The aim of this Special Issue is to present an overview of recent research utilizing medicinal plants for the treatment or cure of diseases.

Dr. Marcus Tullius Scotti
Prof. Dr. Luciana Scotti
Dr. Eugene Muratov
Guest Editors

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Keywords

  • medicinal plants
  • diseases
  • drugs
  • natural products
  • pharmacological activity

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Related Special Issue

Published Papers (2 papers)

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Research

8 pages, 979 KiB  
Communication
Evaluating the Efficacy of an Extract for UV Defense and Mitigation of Oxidative Stress, Transitioning from Biomass to Bioprotection
by Emanuel Vamanu, Milena Lakićević, Nebojša Dedović, Georgiana Dumitru, Ileana Georgiana Badea, Florentina Gatea and Laura Dorina Dinu
Agronomy 2024, 14(10), 2306; https://doi.org/10.3390/agronomy14102306 - 8 Oct 2024
Cited by 1 | Viewed by 929
Abstract
This study evaluated natural extracts from plant biomass for UV protection and oxidative stress reduction. Conducted in Bucharest, Romania, it focused on medicinal mushrooms and pomegranate bark. The biotechnological process involved a two-phase extraction: hot water processing of Ganoderma lucidum, Hericium erinaceus [...] Read more.
This study evaluated natural extracts from plant biomass for UV protection and oxidative stress reduction. Conducted in Bucharest, Romania, it focused on medicinal mushrooms and pomegranate bark. The biotechnological process involved a two-phase extraction: hot water processing of Ganoderma lucidum, Hericium erinaceus, Inonotus obliquus, and Tremella mushrooms, followed by ethanol extraction with pomegranate bark and green tea. The spectrophotometric analysis identified phenolics and flavonoids. The ethanol extract showed higher phenolic content and antioxidant activity, particularly in DPPH radical scavenging. UVB exposure tests demonstrated its protective effect, comparable to vitamin B3, delaying oxidative stress onset by 30 min. This research underscores the potential of using natural biomass extracts in skincare, promoting environmental sustainability and economic viability by converting agricultural waste into valuable bioactive compounds. Full article
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19 pages, 4525 KiB  
Article
Effects of Potassium Application on Growth and Root Metabolism of Salvia miltiorrhiza under Drought Stress
by Jingyu Li, Xiangui Mei, Jin Zhang, Zhenqiao Song, Shiqi Wang, Wensheng Chen, Xin Wei, Xinsheng Fang and Jianhua Wang
Agronomy 2023, 13(11), 2796; https://doi.org/10.3390/agronomy13112796 - 11 Nov 2023
Cited by 7 | Viewed by 1858
Abstract
Potassium application can effectively mitigate the effects of drought stress on plant growth, and few studies have reported its application to the medicinal plant Salvia miltiorrhiza (S. miltiorrhiza). Four experimental treatments were used, including a control (Z1K0), non-drought potassium application (Z1K3), [...] Read more.
Potassium application can effectively mitigate the effects of drought stress on plant growth, and few studies have reported its application to the medicinal plant Salvia miltiorrhiza (S. miltiorrhiza). Four experimental treatments were used, including a control (Z1K0), non-drought potassium application (Z1K3), drought treatments (Z2K0), and drought-stress potassium application (Z2K3). The findings revealed that, in contrast to Z2K0, Z2K3 promoted the absorption of potassium in S. miltiorrhiza, elicited the aggregation of osmoregulatory compounds such as soluble protein and proline, and mitigated membrane impairment as a defense against the deleterious consequences of drought stress. Additionally, we extended our investigation to encompass comprehensive metabolomics analysis of the roots. Interestingly, subsequent root metabolomics analyses demonstrated that the drought application of potassium not only significantly reduced the amino acid content, but also increased the amount of terpenoids and phenolic acids in the roots. Nonetheless, the application of a particular amount of K under moderate drought conditions promoted the growth and yield of S. miltiorrhiza, but proved to be detrimental to its active ingredients. Indeed, the findings of this study offer valuable insights and recommendations for the application of potassium to mitigate the impact of drought stress in S. miltiorrhiza and other medicinal plants. Full article
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