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Colloids Interfaces, Volume 9, Issue 4 (August 2025) – 1 article

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9 pages, 1292 KiB  
Article
Exploring the Feasibility of a Microchip Laser Ablation Method for the Preparation of Biopolymer-Stabilized Gold Nanoparticles: Case Studies with Gelatin and Collagen
by Nazgul Assan, Tomoyuki Suezawa, Yuta Uetake, Yumi Yakiyama, Michiya Matsusaki and Hidehiro Sakurai
Colloids Interfaces 2025, 9(4), 42; https://doi.org/10.3390/colloids9040042 - 20 Jun 2025
Abstract
Introducing small-sized metal nanoparticles directly into biopolymers susceptible to thermal and chemical stimulations remains a significant challenge. Recently, we showed a novel approach to fabricating gold nanoparticles through pulsed laser ablation in liquid (PLAL) using a microchip laser (MCL). Despite its lower pulse [...] Read more.
Introducing small-sized metal nanoparticles directly into biopolymers susceptible to thermal and chemical stimulations remains a significant challenge. Recently, we showed a novel approach to fabricating gold nanoparticles through pulsed laser ablation in liquid (PLAL) using a microchip laser (MCL). Despite its lower pulse energy compared to conventional lasers, this technique demonstrates high ablation efficiency, offering the potential to produce composites without compromising the distinctive structure of biopolymers. As a proof of concept, we successfully generated gelatin-stabilized gold nanoparticles with a smaller size (average diameter of approximately 4 nm), while preserving the unchanged circular dichroism (CD) spectra, indicating the retention of gelatin’s unique structure. Extending this technique to the preparation of type I collagen-stabilized gold nanoparticles yielded non-aggregated nanoparticles, although challenges in yield still persist. These results highlight the potential of the microchip laser ablation technique for producing metal nanoparticles within a vulnerable matrix. Full article
(This article belongs to the Special Issue State of the Art of Colloid and Interface Science in Asia)
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