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Sci, Volume 6, Issue 4

2024 December - 30 articles

Cover Story: The vaginal and uterine microbiota are mainly characterized by the predominance of Lactobacillus, followed by other microbial communities. Moreover, some species and their altered distributions could induce modifications in cell signaling and pathways, which are also featured in the gynecological field. Dysbiotic microbiota could act on tumorigenesis through the persistence of an inflammatory state. One important pathway could be the disruption of the epithelial/mucosal barrier, with the activation of cytokines. In the literature, the compositions of uterine and vaginal microbiota have been analyzed, and their diversity and actions seem to correlate with possible oncological effects in the context of endometrial cancer. View this paper
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Articles (30)

  • Article
  • Open Access
1,511 Views
23 Pages

23 December 2024

Cloud computing has revolutionized the digital era by providing a more efficient, scalable, and cost-effective infrastructure. Secure systems that encrypt and protect data before it is transmitted over a network and stored in the cloud benefit the en...

  • Article
  • Open Access
1 Citations
1,819 Views
20 Pages

Study of Structure and Properties of Thin-Walled Elements of Diamond Cellular Structures Made of Aluminum Alloys via Selective Laser Melting

  • Tatiana Tarasova,
  • Pavel Podrabinnik,
  • Nikolay Babushkin,
  • Andrey Gusarov,
  • Roman Khmyrov,
  • Daniil Strunevich and
  • Sergey N. Grigoriev

20 December 2024

The work is dedicated to the investigation of the possibility of producing and studying the properties of the thin-walled elements of Diamond-type lattice structures, manufactured from the aluminum alloy AlSi10Mg using the selective laser melting met...

  • Article
  • Open Access
1 Citations
3,418 Views
16 Pages

Data-Driven Koopman Based System Identification for Partially Observed Dynamical Systems with Input and Disturbance

  • Patinya Ketthong,
  • Jirayu Samkunta,
  • Nghia Thi Mai,
  • Md Abdus Samad Kamal,
  • Iwanori Murakami and
  • Kou Yamada

19 December 2024

The identification of dynamical systems from data is essential in control theory, enabling the creation of mathematical models that accurately represent the behavior of complex systems. However, real-world applications often present challenges such a...

  • Article
  • Open Access
2 Citations
1,543 Views
18 Pages

Optimizing Cyanobacterial Strain Selection for Antimicrobial Nanoparticle Synthesis: A Comprehensive Analysis

  • Mónica L. Reyes-Galvis,
  • German L. López-Barrera,
  • Néstor A. Urbina-Suarez,
  • Janet B. García-Martínez and
  • Andrés F. Barajas-Solano

10 December 2024

This study presents the synthesis of metal nanoparticles (NPs) with antimicrobial properties from cyanobacterial biomass. Silver (AgNP), copper (CuNP), and zinc (ZnNP) nanoparticles were prepared from exopolysaccharides (EPSs) obtained from isolated...

  • Article
  • Open Access
4 Citations
1,629 Views
18 Pages

Mechanical Performance and Tribological Behavior of WC-ZrO2 Composites with Different Content of Graphene Oxide Fabricated by Spark Plasma Sintering

  • Anton Smirnov,
  • Yuri Pristinskiy,
  • Nestor Washington Solis Pinargote,
  • Yaroslav Meleshkin,
  • Pavel Podrabinnik,
  • Marina Volosova and
  • Sergey Grigoriev

10 December 2024

This paper presents research on the effects of the addition of various contents of graphene oxide and sintering temperature on the mechanical, tribological, and electrical characteristics of WC-ZrO2 composites. Wet processing and spark plasma sinteri...

  • Article
  • Open Access
27 Citations
2,024 Views
16 Pages

An Explainable Multi-Model Stacked Classifier Approach for Predicting Hepatitis C Drug Candidates

  • Teuku Rizky Noviandy,
  • Aga Maulana,
  • Ghifari Maulana Idroes,
  • Rivansyah Suhendra,
  • Razief Perucha Fauzie Afidh and
  • Rinaldi Idroes

6 December 2024

Hepatitis C virus (HCV) infection affects over 71 million people worldwide, leading to severe liver diseases, including cirrhosis and hepatocellular carcinoma. The virus’s high mutation rate complicates current antiviral therapies by promoting...

  • Article
  • Open Access
1 Citations
2,328 Views
14 Pages

An Efficient pH Detector for Water Contamination Based on Mach–Zehnder Interferometer Application

  • Mario Angel Rico-Mendez,
  • Romeo Selvas,
  • Oxana V. Kharissova,
  • Daniel Toral-Acosta,
  • Norma Patricia Puente-Ramirez,
  • Ricardo Chapa-Garcia and
  • Abraham Antonio Gonzalez-Roque

2 December 2024

This paper presents a pH sensor with a Mach–Zehnder Interferometer (MZI) that operates in solutions of 4.0, 7.0, and 10.0. The sensor device consists of two tapered sections with dimensions of 1 mm/1 mm/1 mm for down-taper, waist-length, and up...

  • Review
  • Open Access
2,742 Views
16 Pages

Concept and Design of Cutting Tools for Osseodensification in Implant Dentistry

  • Alexander Isaev,
  • Maria Isaeva,
  • Oleg Yanushevich,
  • Natella Krikheli,
  • Olga Kramar,
  • Aleksandr Tsitsiashvili,
  • Sergey Grigoriev,
  • Catherine Sotova and
  • Pavel Peretyagin

2 December 2024

Osseodensification is an innovative surgical instrumentation technique based on additive (non-cutting) drilling using special burs. It is known from the literature, that the osseodensification burs should operate in a clockwise direction to drill hol...

  • Article
  • Open Access
1,415 Views
10 Pages

2 December 2024

Over 10% of patients undergoing aortic endograft implantation experience endoleaks within a few years. In the case of type 1a endoleaks, a crack forms between the aorta and the prosthesis collar, allowing blood to pass. This blood fills the aneurysma...

  • Article
  • Open Access
1 Citations
2,408 Views
17 Pages

14 November 2024

Metallographic analyses of nodular iron casting methods are based on visual comparisons according to measuring standards. In fact, iron foundry workers have a poster that describes several characterizations of the metallographies and, showing the rea...

  • Article
  • Open Access
2 Citations
3,970 Views
13 Pages

Culture-Independent Quantitative PCR Detected Mobilized Colistin Resistance Genes (mcr-1, mcr-2, mcr-3, mcr-4, and mcr-5) in Chicken Gut Contents in Bangladesh

  • Mamun Al Asad,
  • Md Sarower Hossen Shuvo,
  • Shomaia Yasmin Mitu,
  • Sumia,
  • Md Asief Hossain Zihadi,
  • Ayasha Siddique Shanta,
  • Nahidul Islam,
  • Shamsun Nahar,
  • Brian Godman and
  • Salequl Islam

12 November 2024

Inappropriate antimicrobial use in food animal farming propels antimicrobial resistance (AMR) that affects all health domains. Colistin is a ‘Reserve’ antibiotic for human treatment to be conserved for multidrug-resistant pathogens; howev...

  • Review
  • Open Access
5 Citations
3,860 Views
16 Pages

Microbiota Status and Endometrial Cancer: A Narrative Review About Possible Correlations in Affected Versus Healthy Patients

  • Carmen Imma Aquino,
  • Anthony Nicosia,
  • Arianna Ligori,
  • Agnese Immacolata Volpicelli and
  • Daniela Surico

7 November 2024

(1) Background: Microbiota could be related to tumorigenesis through the persistence of an inflammatory state, also at the endometrial level. Inflammation, in fact, is involved in the promotion of genetic instability and in a favorable microenvironme...

  • Article
  • Open Access
2 Citations
2,097 Views
34 Pages

Deep Fuzzy Credibility Surfaces for Integrating External Databases in the Estimation of Operational Value at Risk

  • Alejandro Peña,
  • Lina M. Sepúlveda-Cano,
  • Juan David Gonzalez-Ruiz,
  • Nini Johana Marín-Rodríguez and
  • Sergio Botero-Botero

5 November 2024

Operational risk (OR) is usually caused by losses due to human errors, inadequate or defective internal processes, system failures, or external events that affect an organization. According to the Basel II agreement, OR is defined by seven risk event...

  • Article
  • Open Access
1 Citations
1,608 Views
11 Pages

Glycosylated Haemoglobin and Quality of Life: A Moderated-Mediation Model for Emotional Intelligence and Affect

  • Aida Pérez-Fernández,
  • Pablo Fernández-Berrocal,
  • Virginia Morillas-Jiménez,
  • Marta Elena Domínguez-López,
  • Mercedes Guerrero-Sánchez,
  • María Soledad Ruiz de Adana-Navas and
  • María José Gutiérrez-Cobo

5 November 2024

Previous research has shown that higher glycosylated haemoglobin (HbA1c) levels are related to poorer quality of life. The objective was to analyse the moderating role of emotional intelligence (EI) in the relationship between HbA1c levels and qualit...

  • Article
  • Open Access
5 Citations
6,801 Views
21 Pages

Implementing Person-Centred Lean Six Sigma to Transform Dermatology Waiting Lists: A Case Study from a Major Teaching Hospital in Dublin, Ireland

  • Aileen Igoe,
  • Seán Paul Teeling,
  • Orla McFeely,
  • Michelle McGuirk,
  • Siobhan Manning,
  • Vanessa Kelly,
  • Heather Coetzee,
  • Úna Cunningham,
  • Karen Connolly and
  • Patsy Lenane

4 November 2024

The study site, a major teaching hospital in Dublin, Ireland, addressed significant challenges within its dermatology service through a comprehensive improvement initiative using a person-centred Lean Six Sigma methodology. Initially, the hospital&rs...

  • Article
  • Open Access
9 Citations
4,309 Views
20 Pages

4 November 2024

The concept of the centaur, symbolizing the fusion of human and machine intelligence, has intrigued visionaries for decades. Recent advancements in artificial intelligence have made this concept not only realizable but also actionable. This synergist...

  • Article
  • Open Access
3 Citations
2,638 Views
15 Pages

Anti-Obesity Potential of Secamone afzelii K. Leaf and Vine Ethanol Extract: Insights into Lipase Inhibition and Secondary Metabolites

  • Franklyn Nonso Iheagwam,
  • Gloria Aniedi Itina,
  • Oyinkansola Ayobolanle Faluyi,
  • Mercy Bella-Omunagbe and
  • Samuel Akpoyowvare Ejoh

1 November 2024

Pancreatic lipase is an enzyme crucial for breaking down fats through hydrolysis, and inhibiting it is important for managing obesity. This study evaluated the lipase inhibitory profile of the leaf (SALE) and vine (SAVE) of Secamone afzelii, explored...

  • Article
  • Open Access
3 Citations
3,243 Views
17 Pages

Evaluating Various Lactose Types as Solid Carriers for Improving Curcumin Solubility in Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDSs) for Oral Administration

  • Panida Teerapipattanapong,
  • Pimrada Jaikon,
  • Nichapa Ningsanonda,
  • Etsuo Yonemochi,
  • Takayuki Furuishi,
  • Namon Hirun and
  • Pakorn Kraisit

1 November 2024

Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result in low bioavailability. This study aims to develop a solid self-nanoemulsifying drug deli...

  • Review
  • Open Access
11 Citations
27,818 Views
24 Pages

Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies

  • Muhammad Redza Fahmi Mod Razif,
  • Siok Yee Chan,
  • Yik-Ling Chew,
  • Masriana Hassan,
  • Shairyzah Ahmad Hisham,
  • Shamima Abdul Rahman,
  • Chun-Wai Mai,
  • Michelle Yee Mun Teo,
  • Phei Er Kee and
  • Kai Bin Liew
  • + 2 authors

25 October 2024

With approximately 18 million people affected by cancer in 2020 globally, scientists are exploring innovative approaches to develop effective treatments for various types of cancer. Traditional chemotherapy drugs, although effective against cancer ce...

  • Article
  • Open Access
1 Citations
3,302 Views
14 Pages

Inspiratory Muscle Performance Is Significantly Related to Acceleration and Deceleration of Isokinetic Knee Extension and Flexion in Division 1 Collegiate Women Soccer Players: A Pilot Study

  • Tiffany Kasa,
  • Luis A. Feigenbaum,
  • Jeffrey T. Ruiz,
  • Meryl Cohen,
  • Julia L. Rapicavoli,
  • Nicholas H. Dibble,
  • Robert O. Poliszuk,
  • Rebecca Jones and
  • Lawrence P. Cahalin

24 October 2024

This study examines the relationship between inspiratory muscle performance (IMP) using the Test of Incremental Respiratory Endurance (TIRE), knee extension (EXT) and flexion (FLEX) acceleration (ACCEL) and deceleration (DECEL) times on an isokinetic...

  • Article
  • Open Access
4 Citations
2,856 Views
14 Pages

Assessing the Antimicrobial Efficacy of Graphene Oxide and Its PEGylated Derivative Against Staphylococcus aureus

  • María F. Gilsanz-Muñoz,
  • Mónica Martínez-Martínez,
  • Javier Pérez-Piñeiro,
  • Miriam Roldán,
  • Mariana P. Arce,
  • Rodrigo Blasco,
  • Laura Rico-San Román,
  • Fernando Esperón-Fajardo,
  • Arisbel Cerpa-Naranjo and
  • Bárbara Martín-Maldonado

24 October 2024

The rise of antimicrobial resistance (AMR) has become a critical health challenge. This, plus the antimicrobial discovery void, had led scientists to search for an effective alternative to antimicrobials. In this context, nanomaterials, such as graph...

  • Review
  • Open Access
2 Citations
5,557 Views
13 Pages

Aberrant Number of Vessels in the Umbilical Cord: What Do We Know?

  • Valentino Remorgida,
  • Anthony Nicosia,
  • Livio Leo,
  • Libera Troìa and
  • Alessandro Libretti

19 October 2024

The umbilical cord, comprising three vital blood vessels, serves as the lifeline between mother and fetus. Prenatal care emphasizes detailed ultrasound examinations of the umbilical cord and postnatal inspections of the placenta and cord to preemptiv...

  • Article
  • Open Access
1 Citations
2,166 Views
12 Pages

Dynamic Perviousness of Thrombi in Acute Ischemic Stroke Predicts Clinical Outcome after Reperfusion Therapy

  • Gergely Bertalan,
  • Miklos Krepuska,
  • Daniel Toth,
  • Jawid Madjidyar,
  • Patrick Thurner,
  • Tilman Schubert and
  • Zsolt Kulcsar

10 October 2024

Background: Acute ischemic stroke (AIS) is one of the leading causes of death in the industrialized world and causes a heavy personal and economic burden. Thrombus perviousness, measured with pre-interventional computed tomography (CT), is a relative...

  • Article
  • Open Access
1 Citations
2,745 Views
18 Pages

Comparative Microstructure Characteristics of Synthesized PbS Nanocrystals and Galena

  • Ehab AlShamaileh,
  • Bashar Lahlouh,
  • Ahmed N. AL-Masri,
  • Mariam Al-Qderat,
  • Wadah Mahmoud,
  • Mohammad Alrbaihat and
  • Iessa Sabbe Moosa

8 October 2024

Lead sulfide (PbS) on the nanoscale was synthesized via a chemical route at room temperature using lead nitrate {Pb(NO3)2} and sodium sulfide (Na2S). The Na2S was prepared at ~105 °C using sodium hydroxide (NaOH) and sulfur (S) powder. The produc...

  • Review
  • Open Access
25 Citations
31,396 Views
38 Pages

Challenges and Opportunities in the Implementation of AI in Manufacturing: A Bibliometric Analysis

  • Lorena Espina-Romero,
  • Humberto Gutiérrez Hurtado,
  • Doile Ríos Parra,
  • Rafael Alberto Vilchez Pirela,
  • Rosa Talavera-Aguirre and
  • Angélica Ochoa-Díaz

3 October 2024

This study explores the evolution and impact of research on the challenges and opportunities in the implementation of artificial intelligence (AI) in manufacturing between 2019 and August 2024. By addressing the growing integration of AI technologies...

  • Review
  • Open Access
4 Citations
2,639 Views
18 Pages

1 October 2024

Background and aim: Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD) affects up to 25% of the population and causes significant morbidity and mortality. Sarcopenia, the lo...

  • Article
  • Open Access
1 Citations
3,380 Views
14 Pages

1 October 2024

This study explores the effects of offshoring and backshoring on value creation per employee within the manufacturing sector by investigating the difference between firms that did and those that did not engage in corresponding relocation activities....

  • Article
  • Open Access
3 Citations
2,825 Views
23 Pages

27 September 2024

Periodontitis is characterized by gingival regression, alveolar bone resorption and the development of deep periodontal pockets that, if left untreated, can lead to tooth loss. Currently, specific biomarkers are needed for the early, objective diagno...

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Sci - ISSN 2413-4155