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Gels, Volume 11, Issue 12

December 2025 - 86 articles

Cover Story: Gelatin-based hydrogels are promising for pharmaceutical and biomedical applications. However, their thermo-sensitivity often restricts practical use. Low-molecular-weight gelatin (LMWG) was obtained through controlled degradation of gelatin with hydroxylamine, and hydrogels were prepared by crosslinking with genipin. LMWG exhibited superior processability, remaining liquid at room temperature, and LMWG-genipin hydrogels showed higher swelling capacity, increased porosity, and improved flexibility without loss of mechanical integrity. Rheological analysis confirmed differences in thermo-sensitivity, and cytocompatibility assays demonstrated low toxicity and proliferation of cells on the materials. The combination of molecular weight modulation and crosslinking by genipin provides an effective strategy to develop gelatin-based hydrogels. View this paper
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Articles (86)

  • Article
  • Open Access
407 Views
13 Pages

Highly Sensitive MXene/MMT-Based Hydrogel for Wearable Sensors and Flexible Supercapacitors

  • Haiyan Zhao,
  • Ziqi Wang,
  • Chaohao Yin,
  • Chu Chen,
  • Li Wang,
  • Xin Zhang and
  • Zhuo Wang

11 December 2025

In this work, a flexible, stretchable, tough, highly ionic conductive, and anti-freezing hydrogel based on acrylamide/two-dimensional transition metal carbide (MXene)/montmorillonite (MMT) was precisely designed. In the hydrogel, MXene and MMT acted...

  • Review
  • Open Access
590 Views
32 Pages

Flexible Polymer Hydrogel Materials for Next-Generation Wearable Energy Storage Technologies

  • Thirukumaran Periyasamy,
  • Shakila Parveen Asrafali and
  • Jaewoong Lee

11 December 2025

The rapid advancement of wearable technology has created an increasing demand for efficient, high-performance energy storage systems that also offer key characteristics such as flexibility, lightweight, and durability. Among the emerging materials, p...

  • Article
  • Open Access
318 Views
13 Pages

Cryoelectrospun Elastin-Alginate Scaffolds Support In Vitro 3D Epithelial-Stromal Cocultures for Salivary Tissue Engineering

  • Pujhitha Ramesh,
  • James Castracane,
  • Melinda Larsen,
  • Deirdre A. Nelson,
  • Susan T. Sharfstein and
  • Yubing Xie

11 December 2025

Bioengineered functional salivary tissues can advance regenerative therapies, preclinical drug testing, and the fundamental understanding of salivary gland dysfunction. Current salivary tissue models are typically Matrigel-based, hydrogel-based or sc...

  • Article
  • Open Access
337 Views
13 Pages

Injectable Hydrogels with Tissue-Adaptive Gelation and Mechanical Properties: Enhancing Softness and Stability

  • Jessica Garcia,
  • Foad Vashahi,
  • Akmal Z. Umarov,
  • Evgeniy V. Dubrovin,
  • Apollinariya Yu. Konyakhina,
  • Elena N. Subcheva,
  • Dimitri A. Ivanov,
  • Andrey V. Dobrynin and
  • Sergei S. Sheiko

11 December 2025

Ultra-soft injectable hydrogels are paramount in biomedical applications such as tissue fillers, drug depots, and tissue regeneration scaffolds. Synthetic approaches relying on linear polymers are confronted by the necessity for significant dilution...

  • Article
  • Open Access
328 Views
17 Pages

Physicochemical, Thermal and Textural Characterization of Olive Pomace Oil and Argan Oil Oleogels Prepared with Different Oleogelators

  • Mine Kırkyol,
  • Ahmet Akköse,
  • Şeyma Şişik Oğraş,
  • Zeynep Feyza Yılmaz Oral,
  • Güzin Kaban and
  • Mükerrem Kaya

11 December 2025

The physicochemical, thermal and textural properties of oleogels formed from olive pomace oil and argan oil using carnauba (KW), candelilla (CW) and sunflower (AW) waxes and their combinations (KCW: 50% carnauba + 50% candelilla wax, KAW: 50% carnaub...

  • Article
  • Open Access
384 Views
21 Pages

10 December 2025

Osteoporotic vertebrae are a uniquely challenging tissue for local delivery due to the complex geometry of cancellous bone, the proximity of the spinal cord, and the need for reliable site retention. These challenges can be met with the use of stimul...

  • Systematic Review
  • Open Access
563 Views
32 Pages

Platelet-Rich Plasma in Veterinary Orthopedic Surgery: A Systematic Review and Quality Evaluation on Liquid- and Gel-Based Therapies in Dogs

  • Francisco Vidal-Negreira,
  • Mario García-González,
  • Victoria Valiño-Cultelli and
  • Antonio González-Cantalapiedra

10 December 2025

The clinical use of platelet-rich plasma (PRP) has gained increasing attention as a regenerative strategy in veterinary orthopedic surgery, yet its efficacy beyond osteoarthritis remains unclear. This systematic review aimed to evaluate the therapeut...

  • Review
  • Open Access
806 Views
49 Pages

10 December 2025

Biocompatible stimuli-sensitive hydrogels are a versatile and promising class of materials with significant potential for various biomedical applications. These ‘’smart’’ hydrogels can dynamically respond to external environme...

  • Article
  • Open Access
447 Views
23 Pages

Epoxy Resin Highly Loaded with an Ionic Liquid: Morphology, Rheology, and Thermophysical Properties

  • Svetlana O. Ilyina,
  • Irina Y. Gorbunova,
  • Michael L. Kerber and
  • Sergey O. Ilyin

10 December 2025

An epoxy resin can be crosslinked with an imidazole-based ionic liquid (IL), whose excess, provided its high melting temperature, can potentially form a dispersed phase to store thermal energy and produce a phase-change material (PCM). This work inve...

  • Article
  • Open Access
255 Views
11 Pages

Pasting and Gel Behavior of Durum Wheat Derivatives

  • Diogo Salvati,
  • Laura Moreno,
  • Juan Manuel Antolín-Rodríguez and
  • Manuel Gómez

10 December 2025

Durum wheat (Triticum durum) is one of the main raw materials in the food industry, used primarily in the production of pasta. During milling, semolina and flour are obtained with different size distributions, and different compositional and function...

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Gels - ISSN 2310-2861