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Journal of Cardiovascular Development and Disease, Volume 2, Issue 4

2015 December - 3 articles

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Articles (3)

  • Feature Paper
  • Review
  • Open Access
24 Citations
8,428 Views
17 Pages

Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole

  • Wenduo Ye,
  • Yingnan Song,
  • Zhen Huang,
  • Yanding Zhang and
  • Yiping Chen

The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the transcriptional factor Shox2. It is noted that ectopic pacemaking activiti...

(This article belongs to the Special Issue Development and Function of the Cardiac Conduction System in Health and Disease)
  • Article
  • Open Access
9 Citations
6,302 Views
9 Pages

Takotsubo Cardiomyopathy: A Long Term Follow-up Shows Benefit with Risk Factor Reduction

  • Koroush Khalighi,
  • Mohammad Umar Farooq,
  • Thein Tun Aung and
  • Swe Oo

Only sparse data was available on long-term of Takotusbo Cardiomyopathy (TC). Previous studies suggested prognosis is not necessarily benign. We report the long-term follow-up of 12 TC patients actively managed with risk factor reduction. Retrospecti...

  • Review
  • Open Access
59 Citations
16,401 Views
25 Pages

Embryonic Development of the Bicuspid Aortic Valve

  • Peter S. Martin,
  • Benjamin Kloesel,
  • Russell A. Norris,
  • Mark Lindsay,
  • David Milan and
  • Simon C. Body

Bicuspid aortic valve (BAV) is the most common congenital valvular heart defect with an overall frequency of 0.5%–1.2%. BAVs result from abnormal aortic cusp formation during valvulogenesis, whereby adjacent cusps fuse into a single large cusp result...

(This article belongs to the Special Issue Genetics and Cardiovascular Development and Disease)
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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425