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Journal of Cardiovascular Development and Disease, Volume 2, Issue 4

December 2015 - 3 articles

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Articles (3)

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Feature Paper
Review

22 Citations

7,745 Views

17 Pages

Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole

Wenduo Ye,
Yingnan Song,
Zhen Huang,
Yanding Zhang and
Yiping Chen

J. Cardiovasc. Dev. Dis.2015, 2(4), 282-298;https://doi.org/10.3390/jcdd2040282

30 November 2015

The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the transcriptional factor Shox2. It is noted that ectopic pacemaking activiti...

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Article

8 Citations

5,818 Views

9 Pages

Takotsubo Cardiomyopathy: A Long Term Follow-up Shows Benefit with Risk Factor Reduction

Koroush Khalighi,
Mohammad Umar Farooq,
Thein Tun Aung and
Swe Oo

J. Cardiovasc. Dev. Dis.2015, 2(4), 273-281;https://doi.org/10.3390/jcdd2040273

16 November 2015

Only sparse data was available on long-term of Takotusbo Cardiomyopathy (TC). Previous studies suggested prognosis is not necessarily benign. We report the long-term follow-up of 12 TC patients actively managed with risk factor reduction. Retrospecti...

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Review

54 Citations

14,938 Views

25 Pages

Embryonic Development of the Bicuspid Aortic Valve

Peter S. Martin,
Benjamin Kloesel,
Russell A. Norris,
Mark Lindsay,
David Milan and
Simon C. Body

J. Cardiovasc. Dev. Dis.2015, 2(4), 248-272;https://doi.org/10.3390/jcdd2040248

2 October 2015

Bicuspid aortic valve (BAV) is the most common congenital valvular heart defect with an overall frequency of 0.5%–1.2%. BAVs result from abnormal aortic cusp formation during valvulogenesis, whereby adjacent cusps fuse into a single large cusp result...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425

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