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Journal of Cardiovascular Development and Disease, Volume 10, Issue 3

March 2023 - 42 articles

Cover Story: Hypoplastic left heart syndrome is a congenital heart condition that requires a series of three surgeries over the first three years of life. In these surgeries, the tricuspid valve of the right side is converted into the regulator of the systemic blood flow. Unfortunately, due to these surgical alterations and the congenital valvular anomalies, these newborns are at risk of developing a retrograde blood flow between the lower and upper chambers in a comorbidity colloquially known as tricuspid regurgitation. In this article, we review the research that has been performed to understand the causes and effects of regurgitation in this unique disease. Additionally, we propose future engineering-focused studies that can improve the diagnosis and treatment techniques. View this paper
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Articles (42)

  • Editorial
  • Open Access
10 Citations
2,647 Views
7 Pages

It has been a long time since, in the spectrum of ischemic (IHD) or coronary (CHD) heart diseases, a differentiation was performed between the forms presenting with and those without pain [...]

  • Article
  • Open Access
4 Citations
2,364 Views
16 Pages

Incidence and Risk Factors for Long-Term Persistence of Diastolic Dysfunction after Aortic Valve Replacement for Aortic Stenosis Compared with Aortic Regurgitation

  • Luminița Iliuță,
  • Andreea Gabriella Andronesi,
  • Alexandru Scafa-Udriște,
  • Bogdan Rădulescu,
  • Horațiu Moldovan,
  • Florentina Ligia Furtunescu and
  • Eugenia Panaitescu

(1) Background: Severe left ventricular (LV) diastolic dysfunction with a restrictive diastolic pattern (LVDFP) is generally associated with a worse prognosis. Its evolution and reversibility in the short- and medium-term after aortic valve replaceme...

  • Article
  • Open Access
6 Citations
2,625 Views
16 Pages

An All-in-One Tool for 2D Atherosclerotic Disease Assessment and 3D Coronary Artery Reconstruction

  • Savvas Kyriakidis,
  • George Rigas,
  • Vassiliki Kigka,
  • Dimitris Zaridis,
  • Georgia Karanasiou,
  • Panagiota Tsompou,
  • Gianna Karanasiou,
  • Lampros Lakkas,
  • Sotirios Nikopoulos and
  • Katerina K. Naka
  • + 3 authors

Diagnosis of coronary artery disease is mainly based on invasive imaging modalities such as X-ray angiography, intravascular ultrasound (IVUS) and optical coherence tomography (OCT). Computed tomography coronary angiography (CTCA) is also used as a n...

  • Case Report
  • Open Access
2 Citations
2,860 Views
9 Pages

Contemporary Management Strategies of Baffle Leaks in Adults with a Failing Systemic Right Ventricle Late after Atrial Switch: A Case Series and Literature Overview

  • Ralph M. L. Neijenhuis,
  • Madelien V. Regeer,
  • Frank van der Kley,
  • Hubert W. Vliegen,
  • Monique R. M. Jongbloed,
  • Philippine Kiès,
  • Martin J. Schalij,
  • J. Wouter Jukema and
  • Anastasia D. Egorova

Baffle leaks are a frequently encountered and often overlooked complication after the atrial switch procedure for transposition of the great arteries. Baffle leaks are present in up to 50% of non-selected patients, and while they initially may not ca...

  • Review
  • Open Access
28 Citations
6,288 Views
20 Pages

The Impact of the Blood Lipids Levels on Arterial Stiffness

  • Mirela Baba,
  • Mihaela Maris,
  • Daniela Jianu,
  • Constantin Tudor Luca,
  • Dana Stoian and
  • Ioana Mozos

Arterial stiffness is a recognized predictor of cardiovascular morbidity and death. It is an early indicator of arteriosclerosis and is influenced by numerous risk factors and biological processes. The lipid metabolism is crucial and standard blood l...

  • Article
  • Open Access
5 Citations
2,699 Views
10 Pages

BioMimics 3D Stent in Femoropopliteal Lesions: 3-Year Outcomes with Propensity Matching for Drug-Coated Balloons

  • Michael Piorkowski,
  • Thomas Zeller,
  • Christos Rammos,
  • Koen Deloose,
  • Klaus Hertting,
  • Volker Sesselmann,
  • Gunnar Tepe,
  • Peter Gaines and
  • Michael Lichtenberg

Background: Through its helical centreline geometry, the BioMimics 3D vascular stent system is designed for the mobile femoropopliteal region, aiming to improve long-term patency and the risk of stent fractures. Methods: MIMICS 3D is a prospective, E...

  • Article
  • Open Access
3 Citations
1,965 Views
12 Pages

Electrocardiographic and other Noninvasive Hemodynamic Markers in Decompensated CHF Patients

  • Gianfranco Piccirillo,
  • Federica Moscucci,
  • Martina Mezzadri,
  • Cristina Caltabiano,
  • Ilaria Di Diego,
  • Myriam Carnovale,
  • Andrea Corrao,
  • Sara Stefano,
  • Claudia Scinicariello and
  • Marco Giuffrè
  • + 4 authors

Acutely decompensated chronic heart failure (adCHF) is among the most important causes of in-hospital mortality. R-wave peak time (RpT) or delayed intrinsicoid deflection was proposed as a risk marker of sudden cardiac death and heart failure decompe...

  • Article
  • Open Access
4 Citations
2,587 Views
15 Pages

Impact of Mitral Regurgitation Recurrence on Mitral Valve Repair for Secondary Ischemic Mitral Regurgitation

  • Antonio Salsano,
  • Antonio Nenna,
  • Nicolas Molinari,
  • Sanjeet Singh Avtaar Singh,
  • Cristiano Spadaccio,
  • Francesco Santini,
  • Massimo Chello,
  • Antonio Fiore and
  • Francesco Nappi

Objectives. The current guidelines still do not include specific recommendations on the use of subvalvular repair (SV-r) for treatment of ischemic mitral regurgitation (IMR). Therefore, the objective of our study was to evaluate the clinical impact o...

  • Review
  • Open Access
10 Citations
2,990 Views
38 Pages

The Role of ncRNAs in Cardiac Infarction and Regeneration

  • Sheila Caño-Carrillo,
  • Estefanía Lozano-Velasco,
  • Juan Manuel Castillo-Casas,
  • Cristina Sánchez-Fernández and
  • Diego Franco

Myocardial infarction is the most prevalent cardiovascular disease worldwide, and it is defined as cardiomyocyte cell death due to a lack of oxygen supply. Such a temporary absence of oxygen supply, or ischemia, leads to extensive cardiomyocyte cell...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425Creative Common CC BY license